Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199419783> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3199419783 endingPage "645" @default.
- W3199419783 startingPage "645" @default.
- W3199419783 abstract "Background: Coagulopathy associated with COVID-19 is one of the main complications, especially in individuals with risk factors. Simultaneously, the use of low molecular weight heparin is the recommended strategy in hospitalized individuals, but the usefulness of other strategies such as DOACs in outpatients is still unknown. Aims: Describe the benefit of the use of rivaroxaban at discharge on the risk of thrombosis in patients discharged from COVID-19.Identify the behavior of Dimero-D at discharge and its modification with anticoagulant therapy. Methods: Randomized 1: 1 study (Rivaroxaban 10mg for 14 days versus observation) at discharge in individuals with COVID-19 who have not required mechanical ventilation. D-dimer was evaluated at 14 and 30 days after discharge in conjunction with a CT angiography at four weeks after hospital discharge. The protocol was developed in the Hospital Regional de Alta Especialidad de Ixtapaluca, authorized by the ethics committee with registration number NR-19-2020. The study is identified in ClinicalTrials.gov with the following registry NCT04508439 Results: Forty individuals were evaluated (20 in each arm) with follow- up greater than 100 days. Gender distribution was equitable in each arm, with a mean age of 50 years (21 to 74 years), 40% (n = 16) were older than 55 years, 27.5% (n = 11) had hypertension and 20% (n = 8) had diabetes. The mean length of hospital stay was 10.5 days (6 to 23 days) treated with oxygen and low molecular weight heparin. At discharge, treatment was started with rivaroxaban 10mg x 14d vs. observation;in the rivaroxaban group, four events were identified (3 hemorrhages / 1 thrombosis), this difference being significant (Log Rank 0.016). Only one thrombosis event (pulmonary embolism) was identified in the rivaroxaban group at eight treatment days. Compared to the diagnosis, DD levels were lower at both 14 and 30 days (p = 0.000, 95% CI, 440.8-1164.9) without finding a difference in those treated with rivaroxaban or observation (p = 0.721, 95% CI, -68.48 to 241.18). Summary/Conclusion: The use of DOACs at discharge does not benefit from an increased risk of hemorrhagic events;the anticoagulant strategy should be individualized, focused only on those patients at very high risk of thrombosis." @default.
- W3199419783 created "2021-09-27" @default.
- W3199419783 creator A5009365551 @default.
- W3199419783 creator A5017987007 @default.
- W3199419783 creator A5022464071 @default.
- W3199419783 creator A5044234925 @default.
- W3199419783 creator A5046372565 @default.
- W3199419783 creator A5051559133 @default.
- W3199419783 creator A5057841440 @default.
- W3199419783 creator A5061140459 @default.
- W3199419783 creator A5069510406 @default.
- W3199419783 creator A5074444394 @default.
- W3199419783 creator A5091499062 @default.
- W3199419783 date "2021-01-01" @default.
- W3199419783 modified "2023-09-24" @default.
- W3199419783 title "Effect of rivaroxaban (10mg) versus observation on the risk of thrombosis at discharge in individuals with covid-19" @default.
- W3199419783 hasPublicationYear "2021" @default.
- W3199419783 type Work @default.
- W3199419783 sameAs 3199419783 @default.
- W3199419783 citedByCount "2" @default.
- W3199419783 countsByYear W31994197832021 @default.
- W3199419783 crossrefType "journal-article" @default.
- W3199419783 hasAuthorship W3199419783A5009365551 @default.
- W3199419783 hasAuthorship W3199419783A5017987007 @default.
- W3199419783 hasAuthorship W3199419783A5022464071 @default.
- W3199419783 hasAuthorship W3199419783A5044234925 @default.
- W3199419783 hasAuthorship W3199419783A5046372565 @default.
- W3199419783 hasAuthorship W3199419783A5051559133 @default.
- W3199419783 hasAuthorship W3199419783A5057841440 @default.
- W3199419783 hasAuthorship W3199419783A5061140459 @default.
- W3199419783 hasAuthorship W3199419783A5069510406 @default.
- W3199419783 hasAuthorship W3199419783A5074444394 @default.
- W3199419783 hasAuthorship W3199419783A5091499062 @default.
- W3199419783 hasBestOaLocation W31994197831 @default.
- W3199419783 hasConcept C126322002 @default.
- W3199419783 hasConcept C141071460 @default.
- W3199419783 hasConcept C187212893 @default.
- W3199419783 hasConcept C2776301958 @default.
- W3199419783 hasConcept C2776884760 @default.
- W3199419783 hasConcept C2777080012 @default.
- W3199419783 hasConcept C2777557582 @default.
- W3199419783 hasConcept C2778661090 @default.
- W3199419783 hasConcept C2779134260 @default.
- W3199419783 hasConcept C2779161974 @default.
- W3199419783 hasConcept C2779936836 @default.
- W3199419783 hasConcept C2780868729 @default.
- W3199419783 hasConcept C3008058167 @default.
- W3199419783 hasConcept C42219234 @default.
- W3199419783 hasConcept C524204448 @default.
- W3199419783 hasConcept C71924100 @default.
- W3199419783 hasConceptScore W3199419783C126322002 @default.
- W3199419783 hasConceptScore W3199419783C141071460 @default.
- W3199419783 hasConceptScore W3199419783C187212893 @default.
- W3199419783 hasConceptScore W3199419783C2776301958 @default.
- W3199419783 hasConceptScore W3199419783C2776884760 @default.
- W3199419783 hasConceptScore W3199419783C2777080012 @default.
- W3199419783 hasConceptScore W3199419783C2777557582 @default.
- W3199419783 hasConceptScore W3199419783C2778661090 @default.
- W3199419783 hasConceptScore W3199419783C2779134260 @default.
- W3199419783 hasConceptScore W3199419783C2779161974 @default.
- W3199419783 hasConceptScore W3199419783C2779936836 @default.
- W3199419783 hasConceptScore W3199419783C2780868729 @default.
- W3199419783 hasConceptScore W3199419783C3008058167 @default.
- W3199419783 hasConceptScore W3199419783C42219234 @default.
- W3199419783 hasConceptScore W3199419783C524204448 @default.
- W3199419783 hasConceptScore W3199419783C71924100 @default.
- W3199419783 hasLocation W31994197831 @default.
- W3199419783 hasLocation W31994197832 @default.
- W3199419783 hasLocation W31994197833 @default.
- W3199419783 hasOpenAccess W3199419783 @default.
- W3199419783 hasPrimaryLocation W31994197831 @default.
- W3199419783 hasRelatedWork W1937154689 @default.
- W3199419783 hasRelatedWork W2080971706 @default.
- W3199419783 hasRelatedWork W2304579011 @default.
- W3199419783 hasRelatedWork W2494843548 @default.
- W3199419783 hasRelatedWork W2533752036 @default.
- W3199419783 hasRelatedWork W2741766490 @default.
- W3199419783 hasRelatedWork W2743166225 @default.
- W3199419783 hasRelatedWork W2767523722 @default.
- W3199419783 hasRelatedWork W2804629086 @default.
- W3199419783 hasRelatedWork W2888169160 @default.
- W3199419783 hasRelatedWork W2896279818 @default.
- W3199419783 hasRelatedWork W2969817746 @default.
- W3199419783 hasRelatedWork W2979536446 @default.
- W3199419783 hasRelatedWork W2981152104 @default.
- W3199419783 hasRelatedWork W3016681923 @default.
- W3199419783 hasRelatedWork W3029618173 @default.
- W3199419783 hasRelatedWork W3207102924 @default.
- W3199419783 hasRelatedWork W3211673888 @default.
- W3199419783 hasRelatedWork W3212403694 @default.
- W3199419783 hasRelatedWork W3213270030 @default.
- W3199419783 hasVolume "5" @default.
- W3199419783 isParatext "false" @default.
- W3199419783 isRetracted "false" @default.
- W3199419783 magId "3199419783" @default.
- W3199419783 workType "article" @default.