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- W3199427706 abstract "Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. Recently, sustained neuroinflammatory response in microglia and astrocytes has been found to cause the deposition of amyloid beta plaques and the hyperphosphorylation of tau protein, thereby accelerating AD progression. The lipoxin A4-transcription factor nuclear factor-kappa B and mitogen-activated protein kinase pathways have been shown to play important roles in the regulation of inflammatory processes. There is growing research-based evidence suggesting that dietary whole-plant foods, such as mushrooms and berries, may be used as inhibitors for anti-neuroinflammation. The beneficial effects of whole-plant foods were mainly attributed to their high contents of functional macromolecules including polysaccharides, polyphenols, and bioactive peptides. This review provides up-to-date information on important molecular signaling pathways of neuroinflammation and discusses the anti-neuroinflammatory effects of whole-plant foods. Further, a critical evaluation of plants’ macromolecular components that have the potential to prevent and/or relieve AD is provided. This work will contribute to better understanding the pathogenetic mechanism of neuroinflammation in AD and provide new approaches for AD therapy." @default.
- W3199427706 created "2021-09-27" @default.
- W3199427706 creator A5018893284 @default.
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- W3199427706 creator A5080455599 @default.
- W3199427706 date "2021-09-23" @default.
- W3199427706 modified "2023-10-16" @default.
- W3199427706 title "Whole-plant foods and their macromolecules: untapped approaches to modulate neuroinflammation in Alzheimer’s disease" @default.
- W3199427706 cites W1140510316 @default.
- W3199427706 cites W1503881649 @default.
- W3199427706 cites W1854174126 @default.
- W3199427706 cites W1893987280 @default.
- W3199427706 cites W1912407135 @default.
- W3199427706 cites W1967086532 @default.
- W3199427706 cites W1967826083 @default.
- W3199427706 cites W1968286822 @default.
- W3199427706 cites W1971988306 @default.
- W3199427706 cites W1976799053 @default.
- W3199427706 cites W1979617519 @default.
- W3199427706 cites W1980377020 @default.
- W3199427706 cites W1989856248 @default.
- W3199427706 cites W2013057056 @default.
- W3199427706 cites W2014583528 @default.
- W3199427706 cites W2018994254 @default.
- W3199427706 cites W2036725502 @default.
- W3199427706 cites W2039852576 @default.
- W3199427706 cites W2043837651 @default.
- W3199427706 cites W2047037522 @default.
- W3199427706 cites W2053184503 @default.
- W3199427706 cites W2066673169 @default.
- W3199427706 cites W2067617634 @default.
- W3199427706 cites W2071201771 @default.
- W3199427706 cites W2079214148 @default.
- W3199427706 cites W2083421143 @default.
- W3199427706 cites W2093351344 @default.
- W3199427706 cites W2149711855 @default.
- W3199427706 cites W2155474314 @default.
- W3199427706 cites W2156014915 @default.
- W3199427706 cites W2171245653 @default.
- W3199427706 cites W2276853091 @default.
- W3199427706 cites W2298656843 @default.
- W3199427706 cites W2397754542 @default.
- W3199427706 cites W2465352031 @default.
- W3199427706 cites W2469199334 @default.
- W3199427706 cites W2496377511 @default.
- W3199427706 cites W2504896963 @default.
- W3199427706 cites W2529568074 @default.
- W3199427706 cites W2530344549 @default.
- W3199427706 cites W2532720480 @default.
- W3199427706 cites W2537675531 @default.
- W3199427706 cites W2550768065 @default.
- W3199427706 cites W2558098655 @default.
- W3199427706 cites W2563737503 @default.
- W3199427706 cites W2568828703 @default.
- W3199427706 cites W2574949547 @default.
- W3199427706 cites W2577677955 @default.
- W3199427706 cites W2587163533 @default.
- W3199427706 cites W2588262749 @default.
- W3199427706 cites W2590940499 @default.
- W3199427706 cites W2592592425 @default.
- W3199427706 cites W2601736196 @default.
- W3199427706 cites W2607621801 @default.
- W3199427706 cites W2608543149 @default.
- W3199427706 cites W2610030175 @default.
- W3199427706 cites W2620539488 @default.
- W3199427706 cites W2620769476 @default.
- W3199427706 cites W2703286065 @default.
- W3199427706 cites W2727582598 @default.
- W3199427706 cites W2734479201 @default.
- W3199427706 cites W2734857931 @default.
- W3199427706 cites W2740079641 @default.
- W3199427706 cites W2743513023 @default.
- W3199427706 cites W2752502405 @default.
- W3199427706 cites W2754194631 @default.
- W3199427706 cites W2760603157 @default.
- W3199427706 cites W2764181426 @default.
- W3199427706 cites W2767591112 @default.
- W3199427706 cites W2774947569 @default.
- W3199427706 cites W2775904333 @default.
- W3199427706 cites W2780295374 @default.
- W3199427706 cites W2780841168 @default.
- W3199427706 cites W2781831583 @default.
- W3199427706 cites W2784939661 @default.
- W3199427706 cites W2789741434 @default.
- W3199427706 cites W2791032058 @default.
- W3199427706 cites W2792402763 @default.
- W3199427706 cites W2793502621 @default.
- W3199427706 cites W2793632245 @default.
- W3199427706 cites W2799946459 @default.
- W3199427706 cites W2800420554 @default.
- W3199427706 cites W2804716129 @default.
- W3199427706 cites W2804842714 @default.
- W3199427706 cites W2809252438 @default.