Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199445993> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3199445993 endingPage "167" @default.
- W3199445993 startingPage "163" @default.
- W3199445993 abstract "A long-term occupational exposure of healthcare staff to cytostatics and ionizing radiation is associated with a possible manifestation of their genotoxic, carcinogenic and teratogenic effects.A total number of 101 employees working with cytostatics or ionizing radiation were examined (some of them repeatedly) in a cancer treatment facility. The control group consisted of 119 persons excluded from the risk exposure. Fluorescence in situ hybridization with three pairs of whole-chromosomal probes and a pancrossomeric probe was used and the translocation frequency was determined.The total number of chromosomal rearrangements of healthcare professionals and control group correlates with age. Taking into account the age dependence, an increased level of chromosomal reconstruction was found in the case of 11 individuals, 10 of which were female, working on the positions of pharmacist, general nurse, physician. A total of 9 of those case involved the work with cytostatics. Five of these cases were re-examined two years later and the observed levels dropped to the control level.The results of biomonitoring should be evaluated on a group basis and individually, taking into account the personal history and possible non-professional effects on individuals - in particular those related to specific environmental measurement results.Key words: preventive medicine - occupational exposure - cytostatic agents - chromosome aberrations - in situ hybridization - fluorescence The authors declare they have no potential conflicts of interest concern ing drugs, products, or services used in the study. The Editorial Board declares that the manuscript met the ICMJE recommendation for biomedical papers. This work was supported by project of Ministry of Health Czech Republic. reg. No. 15-33968A.Submitted: 12. 4. 2018Accepted: 16. 4. 2018." @default.
- W3199445993 created "2021-09-27" @default.
- W3199445993 creator A5018751511 @default.
- W3199445993 creator A5028158809 @default.
- W3199445993 creator A5034158569 @default.
- W3199445993 creator A5040337767 @default.
- W3199445993 creator A5053430574 @default.
- W3199445993 creator A5055650837 @default.
- W3199445993 creator A5059285836 @default.
- W3199445993 creator A5071746273 @default.
- W3199445993 creator A5074109792 @default.
- W3199445993 creator A5074984516 @default.
- W3199445993 date "2018-05-29" @default.
- W3199445993 modified "2023-09-27" @default.
- W3199445993 title "[Biomonitoring of Work with Genotoxic Substances and Factors in a Cancer Treatment Facility]." @default.
- W3199445993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29808695" @default.
- W3199445993 hasPublicationYear "2018" @default.
- W3199445993 type Work @default.
- W3199445993 sameAs 3199445993 @default.
- W3199445993 citedByCount "0" @default.
- W3199445993 crossrefType "journal-article" @default.
- W3199445993 hasAuthorship W3199445993A5018751511 @default.
- W3199445993 hasAuthorship W3199445993A5028158809 @default.
- W3199445993 hasAuthorship W3199445993A5034158569 @default.
- W3199445993 hasAuthorship W3199445993A5040337767 @default.
- W3199445993 hasAuthorship W3199445993A5053430574 @default.
- W3199445993 hasAuthorship W3199445993A5055650837 @default.
- W3199445993 hasAuthorship W3199445993A5059285836 @default.
- W3199445993 hasAuthorship W3199445993A5071746273 @default.
- W3199445993 hasAuthorship W3199445993A5074109792 @default.
- W3199445993 hasAuthorship W3199445993A5074984516 @default.
- W3199445993 hasConcept C104317684 @default.
- W3199445993 hasConcept C104863432 @default.
- W3199445993 hasConcept C109051061 @default.
- W3199445993 hasConcept C121608353 @default.
- W3199445993 hasConcept C126322002 @default.
- W3199445993 hasConcept C138885662 @default.
- W3199445993 hasConcept C18903297 @default.
- W3199445993 hasConcept C27206212 @default.
- W3199445993 hasConcept C2777542201 @default.
- W3199445993 hasConcept C2779457091 @default.
- W3199445993 hasConcept C2987845665 @default.
- W3199445993 hasConcept C2994296024 @default.
- W3199445993 hasConcept C30481170 @default.
- W3199445993 hasConcept C512399662 @default.
- W3199445993 hasConcept C521751864 @default.
- W3199445993 hasConcept C54355233 @default.
- W3199445993 hasConcept C71924100 @default.
- W3199445993 hasConcept C86803240 @default.
- W3199445993 hasConcept C99454951 @default.
- W3199445993 hasConceptScore W3199445993C104317684 @default.
- W3199445993 hasConceptScore W3199445993C104863432 @default.
- W3199445993 hasConceptScore W3199445993C109051061 @default.
- W3199445993 hasConceptScore W3199445993C121608353 @default.
- W3199445993 hasConceptScore W3199445993C126322002 @default.
- W3199445993 hasConceptScore W3199445993C138885662 @default.
- W3199445993 hasConceptScore W3199445993C18903297 @default.
- W3199445993 hasConceptScore W3199445993C27206212 @default.
- W3199445993 hasConceptScore W3199445993C2777542201 @default.
- W3199445993 hasConceptScore W3199445993C2779457091 @default.
- W3199445993 hasConceptScore W3199445993C2987845665 @default.
- W3199445993 hasConceptScore W3199445993C2994296024 @default.
- W3199445993 hasConceptScore W3199445993C30481170 @default.
- W3199445993 hasConceptScore W3199445993C512399662 @default.
- W3199445993 hasConceptScore W3199445993C521751864 @default.
- W3199445993 hasConceptScore W3199445993C54355233 @default.
- W3199445993 hasConceptScore W3199445993C71924100 @default.
- W3199445993 hasConceptScore W3199445993C86803240 @default.
- W3199445993 hasConceptScore W3199445993C99454951 @default.
- W3199445993 hasIssue "Supplementum1" @default.
- W3199445993 hasLocation W31994459931 @default.
- W3199445993 hasOpenAccess W3199445993 @default.
- W3199445993 hasPrimaryLocation W31994459931 @default.
- W3199445993 hasRelatedWork W1982574545 @default.
- W3199445993 hasRelatedWork W2044635529 @default.
- W3199445993 hasRelatedWork W2052582249 @default.
- W3199445993 hasRelatedWork W2082999124 @default.
- W3199445993 hasRelatedWork W2089829550 @default.
- W3199445993 hasRelatedWork W2416450745 @default.
- W3199445993 hasRelatedWork W2558800277 @default.
- W3199445993 hasRelatedWork W2783820308 @default.
- W3199445993 hasRelatedWork W2991015883 @default.
- W3199445993 hasRelatedWork W3161568080 @default.
- W3199445993 hasVolume "31" @default.
- W3199445993 isParatext "false" @default.
- W3199445993 isRetracted "false" @default.
- W3199445993 magId "3199445993" @default.
- W3199445993 workType "article" @default.