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• W3199454979 abstract "Systemic therapy of advanced stage hepatocellular carcinoma (HCC) was limited to the sorafenib in the past decade since 2007. Novel agents including multiple targeting agents, immune checkpoint inhibitors and anti-angiogenesis reported efficacy in treatment. This is the first time, the combination of atezolizumab and bevacizumab as first-line treatment is superior to sorafenib. Standard guideline in advanced HCC was changing. New novel drugs increase in available including multiple targeting agents and immune checkpoint blockade such as Lenvatinib, regorafenib, cabozantinib, ramucirumab and immunotherapy as first line or second line therapy will benefit in term of survival benefit and quality of life in advanced stage or unresectable hepatocellular carcinoma." @default.
• W3199454979 created "2021-09-27" @default.
• W3199454979 creator A5060853148 @default.
• W3199454979 date "2022-06-15" @default.
• W3199454979 modified "2023-10-18" @default.
• W3199454979 title "Systemic Therapy in Hepatocellular Carcinoma" @default.
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• W3199454979 doi "https://doi.org/10.5772/intechopen.100257" @default.
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