Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199668048> ?p ?o ?g. }
- W3199668048 abstract "Objectives Mice are widely used as an animal model for studying human uterine receptivity for embryo implantation. Although transcriptional changes related to mouse uterine receptivity have been determined by using bulk RNA-seq, the data are of limited value because the uterus is a complex organ consisting of many cell types. Here, we aimed to decipher mouse uterine receptivity for embryo implantation at single-cell resolution. Materials and methods Single-cell RNA sequencing was performed for the pre-receptive and the receptive mouse uterus. Gene expression profiles in luminal epithelium and glandular epithelium were validated by comparing against a published laser capture microdissection (LCM)-coupled microarray dataset. Results We revealed 19 distinct cell clusters, including 3 stromal cell clusters, 2 epithelial cell clusters, 1 smooth muscle cell cluster, 4 endothelial cell clusters and 8 immune cell clusters. We identified global gene expression changes associated with uterine receptivity in each cell type. Additionally, we predicted signalling interactions for distinct cell types to understand the crosstalk between the blastocyst and the receptive uterus. Conclusion Our data provide a valuable resource for deciphering the molecular mechanism underlying uterine receptivity in mice." @default.
- W3199668048 created "2021-09-27" @default.
- W3199668048 creator A5014695294 @default.
- W3199668048 creator A5074054114 @default.
- W3199668048 creator A5074501620 @default.
- W3199668048 date "2021-09-23" @default.
- W3199668048 modified "2023-10-15" @default.
- W3199668048 title "Deciphering mouse uterine receptivity for embryo implantation at single‐cell resolution" @default.
- W3199668048 cites W1965853166 @default.
- W3199668048 cites W1967327758 @default.
- W3199668048 cites W1968019951 @default.
- W3199668048 cites W1990498979 @default.
- W3199668048 cites W1994439119 @default.
- W3199668048 cites W1995559307 @default.
- W3199668048 cites W2022295961 @default.
- W3199668048 cites W2023586275 @default.
- W3199668048 cites W2035157303 @default.
- W3199668048 cites W2053571583 @default.
- W3199668048 cites W2054629971 @default.
- W3199668048 cites W2064798635 @default.
- W3199668048 cites W2072840911 @default.
- W3199668048 cites W2091488731 @default.
- W3199668048 cites W2102278945 @default.
- W3199668048 cites W2106561343 @default.
- W3199668048 cites W2108630473 @default.
- W3199668048 cites W2110001173 @default.
- W3199668048 cites W2116015859 @default.
- W3199668048 cites W2133177859 @default.
- W3199668048 cites W2133531826 @default.
- W3199668048 cites W2134526812 @default.
- W3199668048 cites W2139714886 @default.
- W3199668048 cites W2143554821 @default.
- W3199668048 cites W2144656637 @default.
- W3199668048 cites W2146710021 @default.
- W3199668048 cites W2158116208 @default.
- W3199668048 cites W2159675211 @default.
- W3199668048 cites W2164576139 @default.
- W3199668048 cites W2167234515 @default.
- W3199668048 cites W2169274594 @default.
- W3199668048 cites W2178888844 @default.
- W3199668048 cites W2339013618 @default.
- W3199668048 cites W2407257601 @default.
- W3199668048 cites W2533535397 @default.
- W3199668048 cites W2588892416 @default.
- W3199668048 cites W2593182947 @default.
- W3199668048 cites W2625282589 @default.
- W3199668048 cites W2753908609 @default.
- W3199668048 cites W2759615793 @default.
- W3199668048 cites W2788348358 @default.
- W3199668048 cites W2803355270 @default.
- W3199668048 cites W2898759023 @default.
- W3199668048 cites W2912693250 @default.
- W3199668048 cites W2922108535 @default.
- W3199668048 cites W2949177718 @default.
- W3199668048 cites W2949405870 @default.
- W3199668048 cites W2951912016 @default.
- W3199668048 cites W2980793885 @default.
- W3199668048 cites W2990981753 @default.
- W3199668048 cites W2996426371 @default.
- W3199668048 cites W3006650868 @default.
- W3199668048 cites W3007935255 @default.
- W3199668048 cites W3029276601 @default.
- W3199668048 cites W3086909323 @default.
- W3199668048 cites W3107527779 @default.
- W3199668048 cites W4292310542 @default.
- W3199668048 doi "https://doi.org/10.1111/cpr.13128" @default.
- W3199668048 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8560620" @default.
- W3199668048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34558134" @default.
- W3199668048 hasPublicationYear "2021" @default.
- W3199668048 type Work @default.
- W3199668048 sameAs 3199668048 @default.
- W3199668048 citedByCount "15" @default.
- W3199668048 countsByYear W31996680482022 @default.
- W3199668048 countsByYear W31996680482023 @default.
- W3199668048 crossrefType "journal-article" @default.
- W3199668048 hasAuthorship W3199668048A5014695294 @default.
- W3199668048 hasAuthorship W3199668048A5074054114 @default.
- W3199668048 hasAuthorship W3199668048A5074501620 @default.
- W3199668048 hasBestOaLocation W31996680482 @default.
- W3199668048 hasConcept C104317684 @default.
- W3199668048 hasConcept C125965507 @default.
- W3199668048 hasConcept C134018914 @default.
- W3199668048 hasConcept C1491633281 @default.
- W3199668048 hasConcept C150194340 @default.
- W3199668048 hasConcept C16685009 @default.
- W3199668048 hasConcept C16930146 @default.
- W3199668048 hasConcept C189014844 @default.
- W3199668048 hasConcept C196843134 @default.
- W3199668048 hasConcept C2778177303 @default.
- W3199668048 hasConcept C2779066055 @default.
- W3199668048 hasConcept C502942594 @default.
- W3199668048 hasConcept C54355233 @default.
- W3199668048 hasConcept C71924100 @default.
- W3199668048 hasConcept C8415881 @default.
- W3199668048 hasConcept C86803240 @default.
- W3199668048 hasConcept C87073359 @default.
- W3199668048 hasConcept C95444343 @default.
- W3199668048 hasConceptScore W3199668048C104317684 @default.
- W3199668048 hasConceptScore W3199668048C125965507 @default.
- W3199668048 hasConceptScore W3199668048C134018914 @default.