Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199684193> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W3199684193 abstract "Abstract Background: This study aimed to investigate the relationship between community-acquired respiratory distress syndrome toxin (CARDS TX) and HMGB1-TLRs-MyD88 in Mycoplasma pneumoniae pneumonia (MPP) and to examine the immune pathogenesis of Mycoplasma pneumoniae infection. Methods: Children who were diagnosed with MPP and examined by bronchoscopy were included in the MPP group. Additionally, children who underwent bronchoscopy because of bronchial foreign bodies in the same period were included in the control group. Gene expression of CARDS TX, high-mobility group box protein 1 (HMGB1), Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4), myeloid differentiation factor 88 (MyD88), and cluster of differentiation 14 (CD14) in bronchoalveolar lavage fluid (BALF) were detected using real-time reverse transcription-polymerase chain reaction. Correlations between CARDS TX and HMGB1-TLRs-MyD88 were analyzed. Results: CARDS TX, HMGB1, TLR2, MyD88, and CD14 mRNA expression in BALF in the MPP group was significantly higher than that in the control group (all P < 0.05). CARDS TX mRNA expression was positively correlated with HMGB1, TLR2, MyD88, and CD14 mRNA expression (all P < 0.05). Furthermore, HMGB1 mRNA expression was positively correlated with TLR2, MyD88, and CD14 mRNA expression (all P < 0.05). Conclusions: CARDS TX may participate in the immune pathogenesis of MPP through the HMGB1-TLRs/CD14-MyD88 pathway." @default.
- W3199684193 created "2021-09-27" @default.
- W3199684193 creator A5017819589 @default.
- W3199684193 creator A5043415956 @default.
- W3199684193 creator A5063532923 @default.
- W3199684193 creator A5069114611 @default.
- W3199684193 creator A5072424476 @default.
- W3199684193 creator A5078062985 @default.
- W3199684193 creator A5085196011 @default.
- W3199684193 date "2020-07-06" @default.
- W3199684193 modified "2023-09-23" @default.
- W3199684193 title "Investigation of The Relationship Between CARDS TX and The HMGB1-TLRs-MyD88 Signaling Pathway in MPP" @default.
- W3199684193 doi "https://doi.org/10.21203/rs.3.rs-40242/v1" @default.
- W3199684193 hasPublicationYear "2020" @default.
- W3199684193 type Work @default.
- W3199684193 sameAs 3199684193 @default.
- W3199684193 citedByCount "0" @default.
- W3199684193 crossrefType "posted-content" @default.
- W3199684193 hasAuthorship W3199684193A5017819589 @default.
- W3199684193 hasAuthorship W3199684193A5043415956 @default.
- W3199684193 hasAuthorship W3199684193A5063532923 @default.
- W3199684193 hasAuthorship W3199684193A5069114611 @default.
- W3199684193 hasAuthorship W3199684193A5072424476 @default.
- W3199684193 hasAuthorship W3199684193A5078062985 @default.
- W3199684193 hasAuthorship W3199684193A5085196011 @default.
- W3199684193 hasBestOaLocation W31996841931 @default.
- W3199684193 hasConcept C126322002 @default.
- W3199684193 hasConcept C136449434 @default.
- W3199684193 hasConcept C170493617 @default.
- W3199684193 hasConcept C203014093 @default.
- W3199684193 hasConcept C2776709828 @default.
- W3199684193 hasConcept C2777714996 @default.
- W3199684193 hasConcept C2777914695 @default.
- W3199684193 hasConcept C2777961210 @default.
- W3199684193 hasConcept C2778513237 @default.
- W3199684193 hasConcept C2779215961 @default.
- W3199684193 hasConcept C2780545709 @default.
- W3199684193 hasConcept C2780942790 @default.
- W3199684193 hasConcept C2781236682 @default.
- W3199684193 hasConcept C71924100 @default.
- W3199684193 hasConcept C86803240 @default.
- W3199684193 hasConcept C8891405 @default.
- W3199684193 hasConceptScore W3199684193C126322002 @default.
- W3199684193 hasConceptScore W3199684193C136449434 @default.
- W3199684193 hasConceptScore W3199684193C170493617 @default.
- W3199684193 hasConceptScore W3199684193C203014093 @default.
- W3199684193 hasConceptScore W3199684193C2776709828 @default.
- W3199684193 hasConceptScore W3199684193C2777714996 @default.
- W3199684193 hasConceptScore W3199684193C2777914695 @default.
- W3199684193 hasConceptScore W3199684193C2777961210 @default.
- W3199684193 hasConceptScore W3199684193C2778513237 @default.
- W3199684193 hasConceptScore W3199684193C2779215961 @default.
- W3199684193 hasConceptScore W3199684193C2780545709 @default.
- W3199684193 hasConceptScore W3199684193C2780942790 @default.
- W3199684193 hasConceptScore W3199684193C2781236682 @default.
- W3199684193 hasConceptScore W3199684193C71924100 @default.
- W3199684193 hasConceptScore W3199684193C86803240 @default.
- W3199684193 hasConceptScore W3199684193C8891405 @default.
- W3199684193 hasLocation W31996841931 @default.
- W3199684193 hasOpenAccess W3199684193 @default.
- W3199684193 hasPrimaryLocation W31996841931 @default.
- W3199684193 hasRelatedWork W1842438189 @default.
- W3199684193 hasRelatedWork W1914689199 @default.
- W3199684193 hasRelatedWork W2028835724 @default.
- W3199684193 hasRelatedWork W2103675344 @default.
- W3199684193 hasRelatedWork W2152163440 @default.
- W3199684193 hasRelatedWork W2370879936 @default.
- W3199684193 hasRelatedWork W3199684193 @default.
- W3199684193 hasRelatedWork W4225295120 @default.
- W3199684193 hasRelatedWork W4281774408 @default.
- W3199684193 hasRelatedWork W4296981756 @default.
- W3199684193 isParatext "false" @default.
- W3199684193 isRetracted "false" @default.
- W3199684193 magId "3199684193" @default.
- W3199684193 workType "article" @default.