FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199688591> ?p ?o ?g. }

• W3199688591 endingPage "1378" @default.
• W3199688591 startingPage "1378" @default.
• W3199688591 abstract "Systemic lupus erythematosus (SLE) is a chronic autoimmune illness with a growing prevalence in many populations. Few studies have examined genetic predisposition to SLE, so we aimed to examine the clinical impact of the genetic polymorphisms MECP2 rs2734647and TIRAP rs8177374 on the outcomes and therapeutic precision of SLE with and without nephritis. This study included 110 SLE patients—divided into 63 with lupus nephritis (LN), and 47 without nephritis—and 100 controls. Laboratory measurements including CRP, ESR, ACR, CBC, anti-ds-DNA, vitamin A, C3, and C4 were carried out, along with genotyping of MECP2 rs2734647and TIRAP rs8177374 by real-time PCR and sequencing. Treg %, vitamin A, C3, and C4 were lower, whereas Th17 % was higher, in patients vs. controls (p < 0.001). The T allele of MECP2 rs2734647 was higher in LN than in non-nephritis and control subjects. Moreover, the T allele of TIRAP rs8177374 was higher in LN than in non-nephritis and control subjects. The MECP2 and TIRAP genes could play a role in predisposition to SLE, and can also predict disease progress to nephritis, helping to personalize medicine." @default.
• W3199688591 created "2021-09-27" @default.
• W3199688591 creator A5021153925 @default.
• W3199688591 creator A5030977760 @default.
• W3199688591 creator A5039677348 @default.
• W3199688591 creator A5056533101 @default.
• W3199688591 creator A5061985698 @default.
• W3199688591 creator A5063043913 @default.
• W3199688591 creator A5076283583 @default.
• W3199688591 creator A5085494252 @default.
• W3199688591 date "2021-09-18" @default.
• W3199688591 modified "2023-09-27" @default.
• W3199688591 title "Prognostic Impact of Genetic Variants of MECP2 and TIRAP on Clinical Outcomes of Systemic Lupus Erythematosus with and without Nephritis" @default.
• W3199688591 cites W1963756694 @default.
• W3199688591 cites W1989791234 @default.
• W3199688591 cites W1996626475 @default.
• W3199688591 cites W1998055077 @default.
• W3199688591 cites W2035454589 @default.
• W3199688591 cites W2035630729 @default.
• W3199688591 cites W2036971846 @default.
• W3199688591 cites W2045286317 @default.
• W3199688591 cites W2064999867 @default.
• W3199688591 cites W2071614371 @default.
• W3199688591 cites W2075420157 @default.
• W3199688591 cites W2077293946 @default.
• W3199688591 cites W2106054319 @default.
• W3199688591 cites W2106399339 @default.
• W3199688591 cites W2108229001 @default.
• W3199688591 cites W2112275671 @default.
• W3199688591 cites W2114500428 @default.
• W3199688591 cites W2120263268 @default.
• W3199688591 cites W2126113140 @default.
• W3199688591 cites W2130272963 @default.
• W3199688591 cites W2133522461 @default.
• W3199688591 cites W2136032187 @default.
• W3199688591 cites W2140415959 @default.
• W3199688591 cites W2146666642 @default.
• W3199688591 cites W2158273955 @default.
• W3199688591 cites W2161757240 @default.
• W3199688591 cites W2163749231 @default.
• W3199688591 cites W2211185698 @default.
• W3199688591 cites W2286161704 @default.
• W3199688591 cites W2555635521 @default.
• W3199688591 cites W2571226306 @default.
• W3199688591 cites W2754575288 @default.
• W3199688591 cites W2755370518 @default.
• W3199688591 cites W2785694523 @default.
• W3199688591 cites W2885654691 @default.
• W3199688591 cites W2914189813 @default.
• W3199688591 cites W2948488594 @default.
• W3199688591 cites W2965565685 @default.
• W3199688591 cites W2966041078 @default.
• W3199688591 cites W2984752743 @default.
• W3199688591 cites W2989660578 @default.
• W3199688591 cites W2989792666 @default.
• W3199688591 cites W3013929287 @default.
• W3199688591 cites W3023267770 @default.
• W3199688591 cites W3088617648 @default.
• W3199688591 cites W3128658088 @default.
• W3199688591 cites W3158340716 @default.
• W3199688591 cites W3181024808 @default.
• W3199688591 cites W4237271357 @default.
• W3199688591 cites W835546051 @default.
• W3199688591 doi "https://doi.org/10.3390/biom11091378" @default.
• W3199688591 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8466489" @default.
• W3199688591 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34572591" @default.
• W3199688591 hasPublicationYear "2021" @default.
• W3199688591 type Work @default.
• W3199688591 sameAs 3199688591 @default.
• W3199688591 citedByCount "1" @default.
• W3199688591 countsByYear W31996885912022 @default.
• W3199688591 crossrefType "journal-article" @default.
• W3199688591 hasAuthorship W3199688591A5021153925 @default.
• W3199688591 hasAuthorship W3199688591A5030977760 @default.
• W3199688591 hasAuthorship W3199688591A5039677348 @default.
• W3199688591 hasAuthorship W3199688591A5056533101 @default.
• W3199688591 hasAuthorship W3199688591A5061985698 @default.
• W3199688591 hasAuthorship W3199688591A5063043913 @default.
• W3199688591 hasAuthorship W3199688591A5076283583 @default.
• W3199688591 hasAuthorship W3199688591A5085494252 @default.
• W3199688591 hasBestOaLocation W31996885911 @default.
• W3199688591 hasConcept C104317684 @default.
• W3199688591 hasConcept C126322002 @default.
• W3199688591 hasConcept C135763542 @default.
• W3199688591 hasConcept C203014093 @default.
• W3199688591 hasConcept C2777058396 @default.
• W3199688591 hasConcept C2779134260 @default.
• W3199688591 hasConcept C2779912601 @default.
• W3199688591 hasConcept C31467283 @default.
• W3199688591 hasConcept C54355233 @default.
• W3199688591 hasConcept C71924100 @default.
• W3199688591 hasConcept C86803240 @default.
• W3199688591 hasConceptScore W3199688591C104317684 @default.
• W3199688591 hasConceptScore W3199688591C126322002 @default.
• W3199688591 hasConceptScore W3199688591C135763542 @default.
• W3199688591 hasConceptScore W3199688591C203014093 @default.
• W3199688591 hasConceptScore W3199688591C2777058396 @default.
• W3199688591 hasConceptScore W3199688591C2779134260 @default.

• next