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- W3199691618 endingPage "1488" @default.
- W3199691618 startingPage "1479" @default.
- W3199691618 abstract "Autoimmune conditions can occur in a temporary relationship with any malignant lymphoma. In many instances, treatment at diagnosis is not required, but symptomatic autoimmune conditions represent an indication for treatment, particularly in chronic lymphoproliferative diseases. Treatment is selected depending on the predominant condition: autoimmune disease (immunosuppression) or lymphoma (antilymphoma therapy). Steroids and anti-CD20 antibodies are effective against both conditions and may suppress the autoimmune complication for a prolonged period. The efficacy of B-cell receptor inhibitors has provided us with novel insights into the pathophysiology of antibody-producing B cells. Screening for underlying autoimmune conditions is part of the lymphoma workup, because other drugs, such as immunomodulators and checkpoint inhibitors, should be avoided or used with caution. In this article, we discuss diagnostic challenges and treatment approaches for different situations involving lymphomas and autoimmune cytopenias." @default.
- W3199691618 created "2021-09-27" @default.
- W3199691618 creator A5036988600 @default.
- W3199691618 creator A5078621047 @default.
- W3199691618 date "2022-03-10" @default.
- W3199691618 modified "2023-10-03" @default.
- W3199691618 title "How I manage autoimmune cytopenias in patients with lymphoid cancer" @default.
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- W3199691618 doi "https://doi.org/10.1182/blood.2019003686" @default.
- W3199691618 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34517415" @default.
- W3199691618 hasPublicationYear "2022" @default.