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- W3199695514 abstract "Mini-pigs are an adequate biomodel for characterizing the processes of working capacity and endurance, as well as for conducting investigations in the field of sports medicine. For this kind of research, we propose gene targets from the families of cytokine and sirtuin proteins: IL-6, HMGB1, TNF (genes responsible for the synthesis of proteins belonging to the cytokine group) and SIRT (transferase from the family of sirtuin proteins). The SIRT 1 gene presents particular interest as an activator of mitochondrial activity during exercise. Real-time PCR systems were created, allowing assessment of the effect of various drugs on laboratory mini-pigs in preclinical studies." @default.
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- W3199695514 date "2021-09-16" @default.
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- W3199695514 title "Application of Biomolecular Methods for Estimating Cytokine and Sirtuin Expression in Biosimulation of Ultimate Physical Load of Athletes" @default.
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- W3199695514 doi "https://doi.org/10.33647/2074-5982-17-3-10-16" @default.
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