FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199723718> ?p ?o ?g. }

• W3199723718 endingPage "2432" @default.
• W3199723718 startingPage "2432" @default.
• W3199723718 abstract "The altered glucose metabolism characterising cancer cells determines an increased amount of methylglyoxal in their secretome. Previous studies have demonstrated that the methylglyoxal, in turn, modifies the protonation state (PS) of soluble proteins contained in the secretomes of cultivated circulating tumour cells (CTCs). In this study, we describe a method to assess the content of methylglyoxal adducts (MAs) in the secretome by near-infrared (NIR) portable handheld spectroscopy and the extreme learning machine (ELM) algorithm. By measuring the vibration absorption functional groups containing hydrogen, such as C-H, O-H and N-H, NIR generates specific spectra. These spectra reflect alterations of the energy frequency of a sample bringing information about its MAs concentration levels. The algorithm deciphers the information encoded in the spectra and yields a quantitative estimate of the concentration of MAs in the sample. This procedure was used for the comparative analysis of different biological fluids extracted from patients suspected of having cancer (secretome, plasma, serum, interstitial fluid and whole blood) measured directly on the solute left on a surface upon a sample-drop cast and evaporation, without any sample pretreatment. Qualitative and quantitative regression models were built and tested to characterise the different levels of MAs by ELM. The final model we selected was able to automatically segregate tumour from non-tumour patients. The method is simple, rapid and repeatable; moreover, it can be integrated in portable electronic devices for point-of-care and remote testing of patients." @default.
• W3199723718 created "2021-09-27" @default.
• W3199723718 creator A5006800740 @default.
• W3199723718 creator A5012877660 @default.
• W3199723718 creator A5015831580 @default.
• W3199723718 creator A5023530253 @default.
• W3199723718 creator A5035289941 @default.
• W3199723718 creator A5056713401 @default.
• W3199723718 creator A5057584942 @default.
• W3199723718 creator A5074872749 @default.
• W3199723718 creator A5075436791 @default.
• W3199723718 date "2021-09-18" @default.
• W3199723718 modified "2023-10-16" @default.
• W3199723718 title "Methylglyoxal Adducts Levels in Blood Measured on Dried Spot by Portable Near-Infrared Spectroscopy" @default.
• W3199723718 cites W1994505162 @default.
• W3199723718 cites W2012358846 @default.
• W3199723718 cites W2038550525 @default.
• W3199723718 cites W2124056977 @default.
• W3199723718 cites W2330753105 @default.
• W3199723718 cites W2394037489 @default.
• W3199723718 cites W2565532659 @default.
• W3199723718 cites W2573995939 @default.
• W3199723718 cites W2692536589 @default.
• W3199723718 cites W2749438194 @default.
• W3199723718 cites W2755251026 @default.
• W3199723718 cites W2755400959 @default.
• W3199723718 cites W2891382911 @default.
• W3199723718 cites W2900629842 @default.
• W3199723718 cites W2911806527 @default.
• W3199723718 cites W3002646847 @default.
• W3199723718 cites W3014637742 @default.
• W3199723718 cites W3031584248 @default.
• W3199723718 cites W3039980890 @default.
• W3199723718 cites W3092733995 @default.
• W3199723718 cites W3114470805 @default.
• W3199723718 cites W3123875782 @default.
• W3199723718 doi "https://doi.org/10.3390/nano11092432" @default.
• W3199723718 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8472697" @default.
• W3199723718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34578748" @default.
• W3199723718 hasPublicationYear "2021" @default.
• W3199723718 type Work @default.
• W3199723718 sameAs 3199723718 @default.
• W3199723718 citedByCount "3" @default.
• W3199723718 countsByYear W31997237182022 @default.
• W3199723718 countsByYear W31997237182023 @default.
• W3199723718 crossrefType "journal-article" @default.
• W3199723718 hasAuthorship W3199723718A5006800740 @default.
• W3199723718 hasAuthorship W3199723718A5012877660 @default.
• W3199723718 hasAuthorship W3199723718A5015831580 @default.
• W3199723718 hasAuthorship W3199723718A5023530253 @default.
• W3199723718 hasAuthorship W3199723718A5035289941 @default.
• W3199723718 hasAuthorship W3199723718A5056713401 @default.
• W3199723718 hasAuthorship W3199723718A5057584942 @default.
• W3199723718 hasAuthorship W3199723718A5074872749 @default.
• W3199723718 hasAuthorship W3199723718A5075436791 @default.
• W3199723718 hasBestOaLocation W31997237181 @default.
• W3199723718 hasConcept C108204754 @default.
• W3199723718 hasConcept C113196181 @default.
• W3199723718 hasConcept C121332964 @default.
• W3199723718 hasConcept C1276947 @default.
• W3199723718 hasConcept C153642686 @default.
• W3199723718 hasConcept C169760540 @default.
• W3199723718 hasConcept C178790620 @default.
• W3199723718 hasConcept C181199279 @default.
• W3199723718 hasConcept C185592680 @default.
• W3199723718 hasConcept C2778592357 @default.
• W3199723718 hasConcept C3017516299 @default.
• W3199723718 hasConcept C32891209 @default.
• W3199723718 hasConcept C43571822 @default.
• W3199723718 hasConcept C43617362 @default.
• W3199723718 hasConcept C4839761 @default.
• W3199723718 hasConcept C55493867 @default.
• W3199723718 hasConcept C62520636 @default.
• W3199723718 hasConcept C86803240 @default.
• W3199723718 hasConceptScore W3199723718C108204754 @default.
• W3199723718 hasConceptScore W3199723718C113196181 @default.
• W3199723718 hasConceptScore W3199723718C121332964 @default.
• W3199723718 hasConceptScore W3199723718C1276947 @default.
• W3199723718 hasConceptScore W3199723718C153642686 @default.
• W3199723718 hasConceptScore W3199723718C169760540 @default.
• W3199723718 hasConceptScore W3199723718C178790620 @default.
• W3199723718 hasConceptScore W3199723718C181199279 @default.
• W3199723718 hasConceptScore W3199723718C185592680 @default.
• W3199723718 hasConceptScore W3199723718C2778592357 @default.
• W3199723718 hasConceptScore W3199723718C3017516299 @default.
• W3199723718 hasConceptScore W3199723718C32891209 @default.
• W3199723718 hasConceptScore W3199723718C43571822 @default.
• W3199723718 hasConceptScore W3199723718C43617362 @default.
• W3199723718 hasConceptScore W3199723718C4839761 @default.
• W3199723718 hasConceptScore W3199723718C55493867 @default.
• W3199723718 hasConceptScore W3199723718C62520636 @default.
• W3199723718 hasConceptScore W3199723718C86803240 @default.
• W3199723718 hasIssue "9" @default.
• W3199723718 hasLocation W31997237181 @default.
• W3199723718 hasLocation W31997237182 @default.
• W3199723718 hasLocation W31997237183 @default.
• W3199723718 hasLocation W31997237184 @default.
• W3199723718 hasOpenAccess W3199723718 @default.

• next