FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3199741808> ?p ?o ?g. }

• W3199741808 endingPage "5429" @default.
• W3199741808 startingPage "5415" @default.
• W3199741808 abstract "The role of adenylate cyclase 7 (ADCY7) in cancer is still unclear. This study analyzed the interrelationship between the expression and immune function of ADCY7.ADCY7 expression in multiple human cancers was analyzed using the databases of Genotype-Tissue Expression Project (GTEx), Cancer Cell Line Encyclopedia (CCLE), and The Cancer Genome Atlas (TCGA). Correlations among ADCY7 gene expression, mismatch repair (MMR) gene expression, and DNA methyltransferase (DNMT) expression were assessed using Spearman correlation analysis. Univariate survival analysis and Kaplan-Meier (KM) curve were used to examine the effect of ADCY7 expression on prognosis. The Tumor Immune Estimation Resource (TIMER) database was used to evaluate the relationship between ADCY7 gene expression and tumor immune invasion or immune checkpoint gene (ICG) expression.ADCY7 was abnormally expressed in multiple human cancers and was correlated with MMR genes and DNMT expression. Univariate survival analysis and KM curve showed that ADCY7 expression influences the overall survival (OS) of six types of cancer, disease-specific survival (DSS) of eight, and progression-free interval (PFI) of three. The high expression of ADCY7 in OS, DSS, and PFI was strongly associated with poor outcomes in patients with breast cancer and lung squamous cell carcinoma. ADCY7 expression was strongly associated with immune cell infiltration and ICG expression.The results of this study indicated that ADCY7 may be a prognostic biomarker of tumorigenesis. The study may also provide a new perspective on the role of ADCY7 in human cancers." @default.
• W3199741808 created "2021-09-27" @default.
• W3199741808 creator A5001136929 @default.
• W3199741808 creator A5005435867 @default.
• W3199741808 creator A5012737536 @default.
• W3199741808 creator A5023837140 @default.
• W3199741808 creator A5040819519 @default.
• W3199741808 creator A5046092151 @default.
• W3199741808 creator A5078660410 @default.
• W3199741808 creator A5084768117 @default.
• W3199741808 creator A5088069625 @default.
• W3199741808 creator A5091160596 @default.
• W3199741808 date "2021-09-01" @default.
• W3199741808 modified "2023-10-04" @default.
• W3199741808 title "A Pan-Cancer Analysis of the Prognostic Value and Expression of Adenylate Cyclase 7 (ADCY7) in Human Tumors" @default.
• W3199741808 cites W1454504028 @default.
• W3199741808 cites W1901074020 @default.
• W3199741808 cites W1971752180 @default.
• W3199741808 cites W1974537372 @default.
• W3199741808 cites W1996087219 @default.
• W3199741808 cites W2001049490 @default.
• W3199741808 cites W2035252444 @default.
• W3199741808 cites W2035618305 @default.
• W3199741808 cites W2112941906 @default.
• W3199741808 cites W2131838379 @default.
• W3199741808 cites W2149441684 @default.
• W3199741808 cites W2157860451 @default.
• W3199741808 cites W2165167555 @default.
• W3199741808 cites W2170355588 @default.
• W3199741808 cites W2520491400 @default.
• W3199741808 cites W2529308344 @default.
• W3199741808 cites W2590330613 @default.
• W3199741808 cites W2597802455 @default.
• W3199741808 cites W2606495925 @default.
• W3199741808 cites W2622499649 @default.
• W3199741808 cites W2765224588 @default.
• W3199741808 cites W2782768036 @default.
• W3199741808 cites W2796494201 @default.
• W3199741808 cites W2888631183 @default.
• W3199741808 cites W2889646458 @default.
• W3199741808 cites W2900569176 @default.
• W3199741808 cites W2908928362 @default.
• W3199741808 cites W2914335731 @default.
• W3199741808 cites W2918717837 @default.
• W3199741808 cites W2924535664 @default.
• W3199741808 cites W2943690909 @default.
• W3199741808 cites W2987116731 @default.
• W3199741808 cites W3005521521 @default.
• W3199741808 cites W3019946902 @default.
• W3199741808 cites W3021361323 @default.
• W3199741808 cites W3036852566 @default.
• W3199741808 cites W3095540688 @default.
• W3199741808 cites W3133859624 @default.
• W3199741808 cites W4236920686 @default.
• W3199741808 cites W56241122 @default.
• W3199741808 doi "https://doi.org/10.2147/ijgm.s330680" @default.
• W3199741808 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8445103" @default.
• W3199741808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34539183" @default.
• W3199741808 hasPublicationYear "2021" @default.
• W3199741808 type Work @default.
• W3199741808 sameAs 3199741808 @default.
• W3199741808 citedByCount "2" @default.
• W3199741808 countsByYear W31997418082022 @default.
• W3199741808 countsByYear W31997418082023 @default.
• W3199741808 crossrefType "journal-article" @default.
• W3199741808 hasAuthorship W3199741808A5001136929 @default.
• W3199741808 hasAuthorship W3199741808A5005435867 @default.
• W3199741808 hasAuthorship W3199741808A5012737536 @default.
• W3199741808 hasAuthorship W3199741808A5023837140 @default.
• W3199741808 hasAuthorship W3199741808A5040819519 @default.
• W3199741808 hasAuthorship W3199741808A5046092151 @default.
• W3199741808 hasAuthorship W3199741808A5078660410 @default.
• W3199741808 hasAuthorship W3199741808A5084768117 @default.
• W3199741808 hasAuthorship W3199741808A5088069625 @default.
• W3199741808 hasAuthorship W3199741808A5091160596 @default.
• W3199741808 hasBestOaLocation W31997418081 @default.
• W3199741808 hasConcept C104317684 @default.
• W3199741808 hasConcept C10515644 @default.
• W3199741808 hasConcept C121608353 @default.
• W3199741808 hasConcept C126322002 @default.
• W3199741808 hasConcept C143998085 @default.
• W3199741808 hasConcept C150194340 @default.
• W3199741808 hasConcept C18431079 @default.
• W3199741808 hasConcept C190727270 @default.
• W3199741808 hasConcept C203014093 @default.
• W3199741808 hasConcept C2776256026 @default.
• W3199741808 hasConcept C502942594 @default.
• W3199741808 hasConcept C54355233 @default.
• W3199741808 hasConcept C555283112 @default.
• W3199741808 hasConcept C71924100 @default.
• W3199741808 hasConcept C86803240 @default.
• W3199741808 hasConcept C8891405 @default.
• W3199741808 hasConceptScore W3199741808C104317684 @default.
• W3199741808 hasConceptScore W3199741808C10515644 @default.
• W3199741808 hasConceptScore W3199741808C121608353 @default.
• W3199741808 hasConceptScore W3199741808C126322002 @default.
• W3199741808 hasConceptScore W3199741808C143998085 @default.
• W3199741808 hasConceptScore W3199741808C150194340 @default.

• next