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- W3199765281 abstract "… Objective: Aim of the study was to ascertain prospectively the prognostic value of serum uric acid for fetal and maternal outcomes in women with gestational hypertension. Patients and Methods: This prospective study was conducted at department of Gynae & Obs, Maternal and Child Health Center, PIMS Islamabad, from January to December 2003. A total of 200 women with a gestational age >20 weeks, and blood pressure >130/90 mmHg were inducted in the study. At presentation serum uric acid, creatinine, hemoglobin, and platelets were measured along with blood pressure. All patients were divided into group A (uric acid <4.5 mg/dl) and group B (>4.5 mg/dl) and were followed for one month after the delivery to record pregnancy and neonatal outcome. Results: A significant difference (p<0.05) in the levels of uric acid, hemoglobin, platelet count, creatinine and blood pressure was noted between patients of group A and B. A significant decrease (p<0.05) in preterm delivery, baby birth weight and increase in fetal mortality was noted in patients of group B as compared to those of group A. Regarding maternal outcome preeclampsia (p=0.005, CI: 0.143-0.689), deranged liver functions (p=0.000, CI: 0.062-0.397), and disseminated intravascular coagulation (p=0.005; CI: 0.049-0.626) was noted in patients of group B as compared to group A. The patients of Group B showed a significant low birth weight, increased fetal mortality rate (p=0.005, CI: 0.030-0.622) and more chances of shifting neonates to NICU (p=0.002, CI: 0.164-0.667) as compared to those of group A. Conclusions: Hyperuricaemia in setting of gestational hypertension was associated with adverse fetal and maternal outcome." @default.
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- W3199765281 date "2018-12-14" @default.
- W3199765281 modified "2023-10-18" @default.
- W3199765281 title "GESTATIONAL HYPERTENSION" @default.
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- W3199765281 doi "https://doi.org/10.29309/tpmj/2014.21.05.2538" @default.
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