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- W3199769314 abstract "Abstract Unprecedented reversal in regioselectivity during methanolysis of anhydrides due to the change in substitution pattern of fluorine in the phenyl moiety, and the formation of nitrene intercepted intermediates during Curtius rearrangement of the acids were the major impediments for discovering bioactive molecules in beta amyloid cleaving enzyme‐1 (BACE1) program. Solutions to these synthetic challenges, and our investigation into this unexpected change in reactivity are discussed." @default.
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- W3199769314 date "2021-09-24" @default.
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- W3199769314 title "Unprecedented Reversal of Regioselectivity during Methanolysis and an Interception of Curtius Rearrangement" @default.
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- W3199769314 doi "https://doi.org/10.1002/ejoc.202101056" @default.
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