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• W3199946107 abstract "Abstract Background: Ultrasound-guided rhombic intercostal block (RIB) is a novel regional block that provides analgesia for patients who have received video-assisted thoracoscopic surgery (VATS). The anesthetic characteristics of ultrasound-guided RIB with different concentrations of ropivacaine are not known. This research primarily hypothesizes that ultrasound-guided RIB, given in combination with the same volume of different concentrations of ropivacaine, would improve the whole quality of recovery-40 (QoR-40) among patients with VATS. Approaches : This double-blinded, single-center, prospective, and controlled trial randomized 100 patients undergoing VATS to receive RIB. One hundred patients who have received elective VATS and satisfied inclusion standards were fallen into four groups randomly: control group with no RIB and R 0.2% , R 0.3% , and R 0.4% ; they underwent common anesthesia plus the RIB with ropivacaine at 0.2%, 0.3%, and 0.4% in a volume of 30mL. Outcomes: Groups R 0.2% , R 0.3% , and R 0.4% displayed great diversities in the overall QoR-40 scores and QoR-40 dimensions (in addition to psychological support) by comparing with the control group (Group C) ( p <0.001 for all contrasts). Group R 0.3% and R 0.4% displayed great diversities in the overall QoR-40 scores and QoR-40 dimensions (in addition to psychological support) by comparing with the R 0.2% group ( p <0.001 for all contrasts). The overall QoR-40 scores and QoR-40 dimensions (physical comfort [ p =0.585]) did not vary greatly between the Group R 0.3% and R 0.4% ( p >0.05 for all contrasts). Group R 0.2% , R 0.3% and R 0.4% showed significant differences in numerical rating scales (NRS) score region under the curve (AUC) at rest and on movement in 48 hours when compared with the Group C ( p <0.001 for all contrasts). Group R 0.3% and R 0.4% displayed great diversities in NRS score AUC at rest and on movement in 48 hours when compared with the R 0.2% group ( p <0.001 for all contrasts). The NRS mark AUC at rest and on movement in 48 hours did not vary greatly between the Group R 0.3% and R 0.4% ( p >0.05 for all contrasts). Conclusion: It was found that a dose of 0.3% ropivacaine is the best concentration for RIB for patients undergoing VATS. Through growing ropivacaine concentration, the analgesia of the RIB was not improved greatly. Trial registration number: ChiCTR2100046254" @default.
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• W3199946107 date "2021-09-21" @default.
• W3199946107 modified "2023-10-16" @default.
• W3199946107 title "Evaluation of Rhomboid Intercostal Block in Video-assisted Thoracic Surgery: Comparing three Concentrations of Ropivacaine" @default.
• W3199946107 doi "https://doi.org/10.21203/rs.3.rs-895643/v1" @default.
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