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- W3200024248 abstract "Background Enteric fever is a systemic infection with the bacterium Salmonella typhi and paratyphi. Definitive diagnosis of enteric fever requires isolation of S.typhi from blood, bone marrow or stool. In Sudan diagnosis of typhoid fever relies mainly on slide-agglutination test. The objective of this study was to determine the accuracy of slide-agglutination test in diagnosing enteric fever in relation to the definitive diagnostic technique i.e. bacterial isolation.Methods A cross-sectional study was conducted on patients presented to an out-patient clinic complaining of symptoms compatible with enteric fever. Bacterial isolation from Blood, blood-clot and stool was performed on patients diagnosed by slide-agglutination test as positive to enteric fever. Results Salmonella spp were isolated from 42% of the patients who were positive to enteric fever by slide-agglutination test. Most of the isolated Salmonella spp (78%) were from stool samples, 70% were non-typhoidal Salmonella spp. Salmonella typhi was grown from blood as well as blood-clot-samples and represented only 15% of the isolates. Salmonella paratyphi was isolated from the blood clot and stool samples and also represented 15%. Conclusion Diagnosis of typhoid fever based on slide-agglutination test alone could be misleading; it could result in over diagnosis of enteric fever giving inaccurate estimates." @default.
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- W3200024248 date "2021-05-27" @default.
- W3200024248 modified "2023-09-23" @default.
- W3200024248 title "The dilemma of diagnosing typhoid fever in Sudan" @default.
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