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- W3200057760 endingPage "307" @default.
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- W3200057760 abstract "Gastrointestinal and respiratory tract diseases often occur together. There are many overlapping pathologies, leading to the concept of the 'gut-lung axis' in which stimulation on one side triggers a response on the other side. This axis appears to be implicated in infections involving severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which has triggered the global coronavirus disease 2019 (COVID-19) pandemic, in which respiratory symptoms of fever, cough and dyspnoea often occur together with gastrointestinal symptoms such as nausea, vomiting, abdominal pain and diarrhoea. Besides the gut-lung axis, it should be noted that the gut participates in numerous axes which may affect lung function, and consequently the severity of COVID-19, through several pathways. This article focuses on the latest evidence and the mechanisms that drive the operation of the gut-lung axis, and discusses the interaction between the gut-lung axis and its possible involvement in COVID-19 from the perspective of microbiota, microbiota metabolites, microbial dysbiosis, common mucosal immunity and angiotensin-converting enzyme II, raising hypotheses and providing methods to guide future research on this new disease and its treatments." @default.
- W3200057760 created "2021-09-27" @default.
- W3200057760 creator A5001112185 @default.
- W3200057760 creator A5022646640 @default.
- W3200057760 creator A5058885083 @default.
- W3200057760 date "2021-12-01" @default.
- W3200057760 modified "2023-10-12" @default.
- W3200057760 title "Coronavirus disease 2019 and the gut–lung axis" @default.
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