FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200123108> ?p ?o ?g. }

• W3200123108 endingPage "1795" @default.
• W3200123108 startingPage "1786" @default.
• W3200123108 abstract "Polymer nanoparticles (NPs) have a very high potential for applications notably in the biomedical field. However, synthetic polymer NPs cannot yet concurrence the functionalities of proteins, their natural counterparts, notably in terms of size, control over internal structure and interactions with biological environments. We hypothesize that kinetic trapping of polymers bearing oppositely charged groups in NPs could bring a new level of control and allow mimicking the surfaces of proteins.Here, the assembly of mixed-charge polymer NPs through nanoprecipitation of mixtures of oppositely charged polymers is studied. Two series of copolymers made of ethyl methacrylate and 1 to 25 mol% of either methacrylic acid or a trimethylammonium bearing methacrylate are synthesized. These carboxylic acid or trimethylammonium bearing polymers are then mixed in different ratios and nanoprecipitated. The influence of the charge fraction, mixing ratio of the polymers, and precipitation conditions on NP size and surface charge is studied.Using this approach, NPs of less than 25 nm with tunable surface charge from +40 mV to -40 mV are assembled. The resulting NPs are sensitive to pH and certain NP formulations have an isoelectric point allowing repeated charge reversal. Encapsulation of fluorescent dyes yields very bright fluorescent NPs, whose interactions with cells are studied through fluorescence microscopy. The obtained results show the potential of nanoprecipitation of oppositely charged polymers for the design of NPs with precisely tuned surface properties." @default.
• W3200123108 created "2021-09-27" @default.
• W3200123108 creator A5005540624 @default.
• W3200123108 creator A5034051791 @default.
• W3200123108 creator A5088928561 @default.
• W3200123108 creator A5091118127 @default.
• W3200123108 date "2022-02-01" @default.
• W3200123108 modified "2023-10-18" @default.
• W3200123108 title "Protein-like particles through nanoprecipitation of mixtures of polymers of opposite charge" @default.
• W3200123108 cites W1969532160 @default.
• W3200123108 cites W1969927982 @default.
• W3200123108 cites W1972557425 @default.
• W3200123108 cites W1975309755 @default.
• W3200123108 cites W2000473911 @default.
• W3200123108 cites W2001673706 @default.
• W3200123108 cites W2003474213 @default.
• W3200123108 cites W2007851654 @default.
• W3200123108 cites W2010655741 @default.
• W3200123108 cites W2021181435 @default.
• W3200123108 cites W2025540635 @default.
• W3200123108 cites W2073930324 @default.
• W3200123108 cites W2096324068 @default.
• W3200123108 cites W2101332331 @default.
• W3200123108 cites W2140578228 @default.
• W3200123108 cites W2146205672 @default.
• W3200123108 cites W2148172596 @default.
• W3200123108 cites W2160690759 @default.
• W3200123108 cites W2238207809 @default.
• W3200123108 cites W2264711995 @default.
• W3200123108 cites W2287346205 @default.
• W3200123108 cites W2287860045 @default.
• W3200123108 cites W2317950458 @default.
• W3200123108 cites W2327012845 @default.
• W3200123108 cites W2336203968 @default.
• W3200123108 cites W2345916941 @default.
• W3200123108 cites W2413085841 @default.
• W3200123108 cites W2564316966 @default.
• W3200123108 cites W2742287127 @default.
• W3200123108 cites W2770634562 @default.
• W3200123108 cites W2789983246 @default.
• W3200123108 cites W2801407303 @default.
• W3200123108 cites W2897520517 @default.
• W3200123108 cites W2898700998 @default.
• W3200123108 cites W2904046471 @default.
• W3200123108 cites W2905394311 @default.
• W3200123108 cites W2906741363 @default.
• W3200123108 cites W2908120957 @default.
• W3200123108 cites W2911865491 @default.
• W3200123108 cites W2912657837 @default.
• W3200123108 cites W2919876665 @default.
• W3200123108 cites W2946489046 @default.
• W3200123108 cites W2962733971 @default.
• W3200123108 cites W2969876157 @default.
• W3200123108 cites W2996264612 @default.
• W3200123108 cites W2997475719 @default.
• W3200123108 cites W3015771736 @default.
• W3200123108 cites W3023807960 @default.
• W3200123108 cites W3046887530 @default.
• W3200123108 cites W3047360006 @default.
• W3200123108 cites W3048131598 @default.
• W3200123108 cites W3110862794 @default.
• W3200123108 cites W3113687149 @default.
• W3200123108 cites W3159168631 @default.
• W3200123108 cites W3173397475 @default.
• W3200123108 cites W71487545 @default.
• W3200123108 doi "https://doi.org/10.1016/j.jcis.2021.09.080" @default.
• W3200123108 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34600342" @default.
• W3200123108 hasPublicationYear "2022" @default.
• W3200123108 type Work @default.
• W3200123108 sameAs 3200123108 @default.
• W3200123108 citedByCount "5" @default.
• W3200123108 countsByYear W32001231082022 @default.
• W3200123108 countsByYear W32001231082023 @default.
• W3200123108 crossrefType "journal-article" @default.
• W3200123108 hasAuthorship W3200123108A5005540624 @default.
• W3200123108 hasAuthorship W3200123108A5034051791 @default.
• W3200123108 hasAuthorship W3200123108A5088928561 @default.
• W3200123108 hasAuthorship W3200123108A5091118127 @default.
• W3200123108 hasBestOaLocation W32001231081 @default.
• W3200123108 hasConcept C121332964 @default.
• W3200123108 hasConcept C127413603 @default.
• W3200123108 hasConcept C132050475 @default.
• W3200123108 hasConcept C147789679 @default.
• W3200123108 hasConcept C153356533 @default.
• W3200123108 hasConcept C155672457 @default.
• W3200123108 hasConcept C15920480 @default.
• W3200123108 hasConcept C171250308 @default.
• W3200123108 hasConcept C178790620 @default.
• W3200123108 hasConcept C181199279 @default.
• W3200123108 hasConcept C185592680 @default.
• W3200123108 hasConcept C188027245 @default.
• W3200123108 hasConcept C192562407 @default.
• W3200123108 hasConcept C207374878 @default.
• W3200123108 hasConcept C2775968528 @default.
• W3200123108 hasConcept C2780358262 @default.
• W3200123108 hasConcept C42360764 @default.
• W3200123108 hasConcept C521977710 @default.
• W3200123108 hasConcept C62520636 @default.

• next