Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200176817> ?p ?o ?g. }
- W3200176817 endingPage "9965" @default.
- W3200176817 startingPage "9965" @default.
- W3200176817 abstract "The cyclical proliferation of the wild fossorial rodent Arvicola terrestris scherman (ATS) is critical in mid-mountain ecosystems of several European countries. Our goal is to develop an immunocontraceptive vaccine to control their fertility, as a sustainable alternative to chemical poisons currently used. Indeed, these chemicals cause the death of ATS predators and animals sharing their ecosystem, and current laws progressively limit their use, making the development of a targeted vaccination strategy an interesting and efficient alternative. In order to identify species-specific sperm antigens, male and female ATS received subcutaneous injections of whole ATS spermatozoa to elicit an immune response. The analysis of the immune sera led to the identification of 120 immunogenic proteins of sperm cells. Of these, 15 were strictly sperm-specific and located in different regions of the male gamete. Some of these antigens are proteins involved in molecular events essential to the reproductive process, such as sperm-egg interaction, acrosomal reaction, or sperm motility. This approach not only identified a panel of immunogenic proteins from ATS sperm cells, but also demonstrated that some of these proteins trigger an immune response in both male and female ATS. These spermatic antigens are good candidates for the development of a contraceptive vaccine." @default.
- W3200176817 created "2021-09-27" @default.
- W3200176817 creator A5006685225 @default.
- W3200176817 creator A5016895092 @default.
- W3200176817 creator A5027864929 @default.
- W3200176817 creator A5058016909 @default.
- W3200176817 creator A5067788619 @default.
- W3200176817 creator A5086349355 @default.
- W3200176817 date "2021-09-15" @default.
- W3200176817 modified "2023-10-03" @default.
- W3200176817 title "Identification of Arvicola terrestris scherman Sperm Antigens for Immune Contraceptive Purposes" @default.
- W3200176817 cites W1484016220 @default.
- W3200176817 cites W1516346359 @default.
- W3200176817 cites W1623183308 @default.
- W3200176817 cites W1836008096 @default.
- W3200176817 cites W1869735068 @default.
- W3200176817 cites W1970832571 @default.
- W3200176817 cites W1977080140 @default.
- W3200176817 cites W1982718457 @default.
- W3200176817 cites W1984265688 @default.
- W3200176817 cites W1992566140 @default.
- W3200176817 cites W1998199740 @default.
- W3200176817 cites W1999079604 @default.
- W3200176817 cites W2009588348 @default.
- W3200176817 cites W2009746574 @default.
- W3200176817 cites W2009989722 @default.
- W3200176817 cites W2010945726 @default.
- W3200176817 cites W2011863536 @default.
- W3200176817 cites W2013363646 @default.
- W3200176817 cites W2020506481 @default.
- W3200176817 cites W2024649068 @default.
- W3200176817 cites W2037834736 @default.
- W3200176817 cites W2039870853 @default.
- W3200176817 cites W2039954554 @default.
- W3200176817 cites W2040850344 @default.
- W3200176817 cites W2046313546 @default.
- W3200176817 cites W2046858038 @default.
- W3200176817 cites W2051613582 @default.
- W3200176817 cites W2065562431 @default.
- W3200176817 cites W2066563718 @default.
- W3200176817 cites W2071045870 @default.
- W3200176817 cites W2078829611 @default.
- W3200176817 cites W2080914946 @default.
- W3200176817 cites W2082754942 @default.
- W3200176817 cites W2087952403 @default.
- W3200176817 cites W2089735360 @default.
- W3200176817 cites W2101079708 @default.
- W3200176817 cites W2104469233 @default.
- W3200176817 cites W2106285281 @default.
- W3200176817 cites W2111770619 @default.
- W3200176817 cites W2113786459 @default.
- W3200176817 cites W2124745927 @default.
- W3200176817 cites W2138058074 @default.
- W3200176817 cites W2143986719 @default.
- W3200176817 cites W2147693890 @default.
- W3200176817 cites W2157364801 @default.
- W3200176817 cites W2165488829 @default.
- W3200176817 cites W2167671478 @default.
- W3200176817 cites W2218305679 @default.
- W3200176817 cites W2252908939 @default.
- W3200176817 cites W2290337567 @default.
- W3200176817 cites W2307097036 @default.
- W3200176817 cites W2588408472 @default.
- W3200176817 cites W2606559217 @default.
- W3200176817 cites W2609522512 @default.
- W3200176817 cites W2793503070 @default.
- W3200176817 cites W2890158603 @default.
- W3200176817 cites W2945214650 @default.
- W3200176817 cites W2948641210 @default.
- W3200176817 cites W2981251447 @default.
- W3200176817 cites W3002882838 @default.
- W3200176817 cites W4233445934 @default.
- W3200176817 cites W2034198829 @default.
- W3200176817 doi "https://doi.org/10.3390/ijms22189965" @default.
- W3200176817 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8465135" @default.
- W3200176817 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34576131" @default.
- W3200176817 hasPublicationYear "2021" @default.
- W3200176817 type Work @default.
- W3200176817 sameAs 3200176817 @default.
- W3200176817 citedByCount "2" @default.
- W3200176817 countsByYear W32001768172022 @default.
- W3200176817 countsByYear W32001768172023 @default.
- W3200176817 crossrefType "journal-article" @default.
- W3200176817 hasAuthorship W3200176817A5006685225 @default.
- W3200176817 hasAuthorship W3200176817A5016895092 @default.
- W3200176817 hasAuthorship W3200176817A5027864929 @default.
- W3200176817 hasAuthorship W3200176817A5058016909 @default.
- W3200176817 hasAuthorship W3200176817A5067788619 @default.
- W3200176817 hasAuthorship W3200176817A5086349355 @default.
- W3200176817 hasBestOaLocation W32001768171 @default.
- W3200176817 hasConcept C147483822 @default.
- W3200176817 hasConcept C203014093 @default.
- W3200176817 hasConcept C22070199 @default.
- W3200176817 hasConcept C2776803348 @default.
- W3200176817 hasConcept C2781087480 @default.
- W3200176817 hasConcept C54355233 @default.
- W3200176817 hasConcept C86803240 @default.
- W3200176817 hasConcept C8891405 @default.