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- W3200280820 abstract "Ganoderma tsugae is an endemic medicinal mushroom in Northeast China, providing important source of pharmaceutical product. Comparing with other Ganoderma species, wild G. tsugae can utilize coniferous wood. However, functional genes related to medicinal component synthesis and the genetic mechanism of conifer substrate utilization is still obscure. Here, we assembled a high-quality G. tsugae genome with 18 contigs and 98.5% BUSCO genes and performed the comparative genomics with other Ganoderma species. G. tsugae diverged from their common ancestor of G. lingzhi and G. sinense about 21 million years ago. Genes in G. tsugae -specific and G. tsugae -expanded gene families, such as salh , phea , cyp53a1 , and cyp102a , and positively selected genes, such as glpk and amie , were functionally enriched in plant-pathogen interaction, benzoate degradation, and fanconi anemia pathway. Those functional genes might contribute to conifer substrate utilization of G. tsugae . Meanwhile, gene families in the terpene synthesis were identified and genome-wide SNP variants were detected in population. Finally, the study provided valuable genomic resources and offered useful hints for the functional gene mapping and investigation of key gene contributing to conifer cultivation substrate utilization and medicinal component biosynthesis." @default.
- W3200280820 created "2021-09-27" @default.
- W3200280820 creator A5021355100 @default.
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- W3200280820 creator A5087863284 @default.
- W3200280820 date "2021-09-16" @default.
- W3200280820 modified "2023-09-26" @default.
- W3200280820 title "Genome of Ganoderma Species Provides Insights Into the Evolution, Conifers Substrate Utilization, and Terpene Synthesis for Ganoderma tsugae" @default.
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- W3200280820 doi "https://doi.org/10.3389/fmicb.2021.724451" @default.
- W3200280820 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8481371" @default.
- W3200280820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34603250" @default.
- W3200280820 hasPublicationYear "2021" @default.
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