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- W3200310633 abstract "Mung bean contains various neuroprotective polyphenols, so it might be a healthy food for Alzheimer's disease (AD) prevention. Totally, 19 major phenolic compounds were quantified in mung bean, including 10 phenolic acids and 9 flavonoids. After summarizing their contents and effective doses in rodent AD models, it was speculated that vitexin, isovitexin, sinapic acid, and ferulic acid might be the major bioactive compounds for mung bean-mediated neuroprotection. The mechanisms involved inhibition of β-amyloidogenesis, tau hyperphosphorylation, oxidative stress, and neuroinflammation, and promotion of autophagy and acetylcholinesterase enzyme activity. Notably, the neuroprotective phenolic profile in mung bean changed after germination, with decreased vitexin and isovitexin, and increased rutin, isoquercitrin, isorhamnetin, and caffeic acid detected. However, only studies of individual phenolic compounds in mung bean are published at present. Hence, further studies are needed to elucidate the neuroprotective activities and mechanisms of extractions of mung bean seeds and sprouts, and the synergism between different phenolic compounds." @default.
- W3200310633 created "2021-09-27" @default.
- W3200310633 creator A5001131711 @default.
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- W3200310633 creator A5048826252 @default.
- W3200310633 creator A5053483245 @default.
- W3200310633 date "2021-09-22" @default.
- W3200310633 modified "2023-09-23" @default.
- W3200310633 title "Neuroprotective Potential of Mung Bean (<i>Vigna radiata</i> L.) Polyphenols in Alzheimer’s Disease: A Review" @default.
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