Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200380950> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3200380950 abstract "Hemodynamic instability is a frequent adverse effect following administration of dexmedetomidine (DMED). In this study, we evaluated the incidence of DMED-induced hemodynamic instability and its predictive factors in clinical regional anesthesia practice.One hundred sixteen patients who underwent orthopedic upper limb surgery under brachial plexus block with intravenous DMED administration were retrospectively identified. The primary outcome was the incidence of DMED-induced hemodynamic instability. The participants were allocated to a stable or unstable group by their hemodynamic instability status. Patients' characteristics were compared between the groups. The relationship between the potential risk factors and development of DMED-induced hemodynamic instability was analyzed with a logistic regression model.DMED-induced hemodynamic instability was observed in 14.7% of patients (17/116). The unstable group had more women than the stable group (76.5% vs. 39.4%, P = 0.010). When patients were classified into four subgroup according to body mass index (underweight, normal weight, overweight, and obesity), there was significant difference in the composition of the subgroups in the two groups (P = 0.008). In univariate analysis, female sex, obesity, and pre-existing hypertension were significant predictors of DMED-induced hemodynamic instability. Multivariate analysis demonstrated that female sex (adjusted OR 3.86, CI 1.09; 13.59, P = 0.036) and obesity (adjusted OR 6.41, CI 1.22; 33.57, P = 0.028) were independent predictors of DMED-induced hemodynamic instability.Female and obese patients are more likely to have hemodynamic instability following intravenous DMED administration in clinical regional anesthesia practice. This study suggests that DMED dose may be diminished to prevent hypotensive risk in these populations.This article was retrospectively registered at WHO clinical trial registry platform (Trial number: KCT0005977 )." @default.
- W3200380950 created "2021-09-27" @default.
- W3200380950 creator A5036219483 @default.
- W3200380950 creator A5049094437 @default.
- W3200380950 creator A5057844283 @default.
- W3200380950 creator A5088786996 @default.
- W3200380950 date "2021-09-16" @default.
- W3200380950 modified "2023-10-09" @default.
- W3200380950 title "Dexmedetomidine-induced hemodynamic instability in patients undergoing orthopedic upper limb surgery under brachial plexus block: a retrospective study" @default.
- W3200380950 cites W1464809537 @default.
- W3200380950 cites W1774015459 @default.
- W3200380950 cites W1993435783 @default.
- W3200380950 cites W2000018178 @default.
- W3200380950 cites W2050579082 @default.
- W3200380950 cites W2059069143 @default.
- W3200380950 cites W2062091876 @default.
- W3200380950 cites W2067978100 @default.
- W3200380950 cites W2068469916 @default.
- W3200380950 cites W2102518307 @default.
- W3200380950 cites W2107564745 @default.
- W3200380950 cites W2110858892 @default.
- W3200380950 cites W2135672238 @default.
- W3200380950 cites W2410254545 @default.
- W3200380950 cites W2514068953 @default.
- W3200380950 cites W2572066098 @default.
- W3200380950 cites W2576234460 @default.
- W3200380950 cites W2745615401 @default.
- W3200380950 cites W2954793850 @default.
- W3200380950 cites W2992810089 @default.
- W3200380950 cites W3014420666 @default.
- W3200380950 cites W4254883573 @default.
- W3200380950 doi "https://doi.org/10.1186/s12871-021-01416-4" @default.
- W3200380950 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8444554" @default.
- W3200380950 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34525975" @default.
- W3200380950 hasPublicationYear "2021" @default.
- W3200380950 type Work @default.
- W3200380950 sameAs 3200380950 @default.
- W3200380950 citedByCount "3" @default.
- W3200380950 countsByYear W32003809502022 @default.
- W3200380950 countsByYear W32003809502023 @default.
- W3200380950 crossrefType "journal-article" @default.
- W3200380950 hasAuthorship W3200380950A5036219483 @default.
- W3200380950 hasAuthorship W3200380950A5049094437 @default.
- W3200380950 hasAuthorship W3200380950A5057844283 @default.
- W3200380950 hasAuthorship W3200380950A5088786996 @default.
- W3200380950 hasBestOaLocation W32003809501 @default.
- W3200380950 hasConcept C126322002 @default.
- W3200380950 hasConcept C141071460 @default.
- W3200380950 hasConcept C167135981 @default.
- W3200380950 hasConcept C178853913 @default.
- W3200380950 hasConcept C2776814716 @default.
- W3200380950 hasConcept C2779526319 @default.
- W3200380950 hasConcept C2781302539 @default.
- W3200380950 hasConcept C42219234 @default.
- W3200380950 hasConcept C68312169 @default.
- W3200380950 hasConcept C71924100 @default.
- W3200380950 hasConceptScore W3200380950C126322002 @default.
- W3200380950 hasConceptScore W3200380950C141071460 @default.
- W3200380950 hasConceptScore W3200380950C167135981 @default.
- W3200380950 hasConceptScore W3200380950C178853913 @default.
- W3200380950 hasConceptScore W3200380950C2776814716 @default.
- W3200380950 hasConceptScore W3200380950C2779526319 @default.
- W3200380950 hasConceptScore W3200380950C2781302539 @default.
- W3200380950 hasConceptScore W3200380950C42219234 @default.
- W3200380950 hasConceptScore W3200380950C68312169 @default.
- W3200380950 hasConceptScore W3200380950C71924100 @default.
- W3200380950 hasIssue "1" @default.
- W3200380950 hasLocation W32003809501 @default.
- W3200380950 hasLocation W32003809502 @default.
- W3200380950 hasLocation W32003809503 @default.
- W3200380950 hasLocation W32003809504 @default.
- W3200380950 hasOpenAccess W3200380950 @default.
- W3200380950 hasPrimaryLocation W32003809501 @default.
- W3200380950 hasRelatedWork W2007557167 @default.
- W3200380950 hasRelatedWork W2345292858 @default.
- W3200380950 hasRelatedWork W2358787319 @default.
- W3200380950 hasRelatedWork W2362858823 @default.
- W3200380950 hasRelatedWork W2384777835 @default.
- W3200380950 hasRelatedWork W3156307398 @default.
- W3200380950 hasRelatedWork W3194936658 @default.
- W3200380950 hasRelatedWork W4289533634 @default.
- W3200380950 hasRelatedWork W4297249327 @default.
- W3200380950 hasRelatedWork W2954502884 @default.
- W3200380950 hasVolume "21" @default.
- W3200380950 isParatext "false" @default.
- W3200380950 isRetracted "false" @default.
- W3200380950 magId "3200380950" @default.
- W3200380950 workType "article" @default.