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• W3200422605 abstract "Objective This study aimed to translate and validate DN4 questionnaire into Nepalese version. Design An observational study design was adopted. Setting A tertiary level teaching hospital of Kathmandu, Nepal Participants We included 166 purposively selected patients visiting pain clinics of the hospital over one year time Methods The Nepalese version of the DN4 questionnaire was used to detect neuropathic pain among the chronic pain patients of the hospital. The English version of the questionnaire was translated into Nepali based on the standard guideline with the help of linguistic experts. The patients diagnosed with nociceptive or neuropathic pain were interviewed twice in two weeks interval. We analyzed test-retest reliability and strength of the test by using Intra-class correlation coefficient (ICC) and Receiver Operating Characteristics (ROC) Curve, respectively. Internal Consistency reliability was assessed using Cronbachs alpha (r). Diagnostic accuracy was assessed through measures like sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratio. Results The study showed a good test-retest reliability (ICC=0.877) and internal consistency reliability (r =0.710). The AUC were 0.932 (0.894-0.971) for the first test, and 0.955 (0.921-0.990) for the second test. The sensitivity and specificity values were found highest at the 4 cut-off point (4 score out of 10), that are 75% and 95.3% for test 1, and 76.2% and 98.8% for test 2. Similarly positive and negative predictive values are 93.8% and 80.4% respectively for the first test and 98.4% and 81.7% respectively for the second test. Conclusions The Nepalese version of DN4 questionnaire is a valid and reliable tool for the diagnosis of neuropathic pain. This can be used for screening neuropathic and non-neuropathic pain in clinical as well as epidemiological settings. Key words: Nepal; neuropathic pain; questionnaire; translate" @default.
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• W3200422605 date "2021-09-21" @default.
• W3200422605 modified "2023-09-27" @default.
• W3200422605 title "Nepalese version of Douleur Neuropathique 4 (DN4) questionnaire for Assessment of Neuropathic pain: A Validation Study" @default.
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• W3200422605 doi "https://doi.org/10.1101/2021.09.17.21263734" @default.
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