Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200425550> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3200425550 abstract "Although patients with malignant bile duct obstruction due to pancreatic cancer are often initially treated with biliary stent placement, concurrent chemoradiotherapy with stents poses a potential risk of increased toxicity. This retrospective study aimed to evaluate the safety of biliary stent placement followed by definitive concurrent chemoradiotherapy in patients with pancreatic cancer.Patients with pancreatic cancer who underwent either a plastic stent or a self-expanding metallic stent placement for malignant bile duct obstruction before definitive concurrent chemoradiotherapy were retrospectively reviewed. Radiotherapy was delivered in 1.8 Gy per fraction to a total dose of 50.4 Gy. Gemcitabine, TS-1 plus Gemcitabine, or TS-1 was the concurrent chemotherapy/regimen. The primary endpoint was the rate of biliary stent-related toxicities, defined as biliary bleeding, duodenal perforation, or bile duct perforation.Thirty patients were included. Plastic stents were placed in 23 patients and self-expanding metallic stent in seven patients at the start of irradiation. The median follow-up time was 20 (range, 2-63) months, and 27 patients (90%) completed concurrent chemoradiotherapy. Biliary stent-related toxicity (grade 3 biliary bleeding) was confirmed in one patient (3%) with a plastic stent 9 months after concurrent chemoradiotherapy. The median duration of locoregional control, progression-free survival, and overall survival were 31.1, 7.3, and 10.5 months, respectively.Stent placement followed by concurrent chemoradiotherapy was not associated with an apparent increase in toxicity and may be an appropriate treatment for patients with locally advanced pancreatic head cancer with bile duct obstruction." @default.
- W3200425550 created "2021-09-27" @default.
- W3200425550 creator A5037020713 @default.
- W3200425550 creator A5050196444 @default.
- W3200425550 creator A5066700160 @default.
- W3200425550 creator A5074774211 @default.
- W3200425550 creator A5081787271 @default.
- W3200425550 date "2021-01-01" @default.
- W3200425550 modified "2023-10-01" @default.
- W3200425550 title "Safety of biliary stent placement followed by definitive chemoradiotherapy in patients with pancreatic cancer with bile duct obstruction" @default.
- W3200425550 cites W158217847 @default.
- W3200425550 cites W1974635368 @default.
- W3200425550 cites W2019607817 @default.
- W3200425550 cites W2040677795 @default.
- W3200425550 cites W2071673212 @default.
- W3200425550 cites W2094568113 @default.
- W3200425550 cites W2103711657 @default.
- W3200425550 cites W2121960517 @default.
- W3200425550 cites W2123768459 @default.
- W3200425550 cites W2139596700 @default.
- W3200425550 cites W2172089182 @default.
- W3200425550 cites W2331899360 @default.
- W3200425550 cites W2573971665 @default.
- W3200425550 cites W2591717879 @default.
- W3200425550 cites W2911121586 @default.
- W3200425550 cites W2960637071 @default.
- W3200425550 cites W2991186073 @default.
- W3200425550 doi "https://doi.org/10.21037/jgo-21-198" @default.
- W3200425550 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8576232" @default.
- W3200425550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34790390" @default.
- W3200425550 hasPublicationYear "2021" @default.
- W3200425550 type Work @default.
- W3200425550 sameAs 3200425550 @default.
- W3200425550 citedByCount "0" @default.
- W3200425550 crossrefType "journal-article" @default.
- W3200425550 hasAuthorship W3200425550A5037020713 @default.
- W3200425550 hasAuthorship W3200425550A5050196444 @default.
- W3200425550 hasAuthorship W3200425550A5066700160 @default.
- W3200425550 hasAuthorship W3200425550A5074774211 @default.
- W3200425550 hasAuthorship W3200425550A5081787271 @default.
- W3200425550 hasBestOaLocation W32004255501 @default.
- W3200425550 hasConcept C121608353 @default.
- W3200425550 hasConcept C126322002 @default.
- W3200425550 hasConcept C126838900 @default.
- W3200425550 hasConcept C141071460 @default.
- W3200425550 hasConcept C191897082 @default.
- W3200425550 hasConcept C192562407 @default.
- W3200425550 hasConcept C2775982439 @default.
- W3200425550 hasConcept C2776694085 @default.
- W3200425550 hasConcept C2778424827 @default.
- W3200425550 hasConcept C2778456384 @default.
- W3200425550 hasConcept C2778527123 @default.
- W3200425550 hasConcept C2778583881 @default.
- W3200425550 hasConcept C2778764654 @default.
- W3200425550 hasConcept C2778975757 @default.
- W3200425550 hasConcept C2779777945 @default.
- W3200425550 hasConcept C2780210213 @default.
- W3200425550 hasConcept C2780258809 @default.
- W3200425550 hasConcept C509974204 @default.
- W3200425550 hasConcept C71924100 @default.
- W3200425550 hasConcept C90924648 @default.
- W3200425550 hasConceptScore W3200425550C121608353 @default.
- W3200425550 hasConceptScore W3200425550C126322002 @default.
- W3200425550 hasConceptScore W3200425550C126838900 @default.
- W3200425550 hasConceptScore W3200425550C141071460 @default.
- W3200425550 hasConceptScore W3200425550C191897082 @default.
- W3200425550 hasConceptScore W3200425550C192562407 @default.
- W3200425550 hasConceptScore W3200425550C2775982439 @default.
- W3200425550 hasConceptScore W3200425550C2776694085 @default.
- W3200425550 hasConceptScore W3200425550C2778424827 @default.
- W3200425550 hasConceptScore W3200425550C2778456384 @default.
- W3200425550 hasConceptScore W3200425550C2778527123 @default.
- W3200425550 hasConceptScore W3200425550C2778583881 @default.
- W3200425550 hasConceptScore W3200425550C2778764654 @default.
- W3200425550 hasConceptScore W3200425550C2778975757 @default.
- W3200425550 hasConceptScore W3200425550C2779777945 @default.
- W3200425550 hasConceptScore W3200425550C2780210213 @default.
- W3200425550 hasConceptScore W3200425550C2780258809 @default.
- W3200425550 hasConceptScore W3200425550C509974204 @default.
- W3200425550 hasConceptScore W3200425550C71924100 @default.
- W3200425550 hasConceptScore W3200425550C90924648 @default.
- W3200425550 hasLocation W32004255501 @default.
- W3200425550 hasLocation W32004255502 @default.
- W3200425550 hasLocation W32004255503 @default.
- W3200425550 hasOpenAccess W3200425550 @default.
- W3200425550 hasPrimaryLocation W32004255501 @default.
- W3200425550 hasRelatedWork W12056025 @default.
- W3200425550 hasRelatedWork W12173777 @default.
- W3200425550 hasRelatedWork W150317 @default.
- W3200425550 hasRelatedWork W15661769 @default.
- W3200425550 hasRelatedWork W16312876 @default.
- W3200425550 hasRelatedWork W1797249 @default.
- W3200425550 hasRelatedWork W18838644 @default.
- W3200425550 hasRelatedWork W19691781 @default.
- W3200425550 hasRelatedWork W3822548 @default.
- W3200425550 hasRelatedWork W619133 @default.
- W3200425550 isParatext "false" @default.
- W3200425550 isRetracted "false" @default.
- W3200425550 magId "3200425550" @default.
- W3200425550 workType "article" @default.