FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200438894> ?p ?o ?g. }

• W3200438894 endingPage "176" @default.
• W3200438894 startingPage "172" @default.
• W3200438894 abstract "This work is an attempt to analyze the data on the mechanisms of cardio- and nephroprotection of drugs of the SGLT2 inhibitor group (Sodium / glucose cotransporter 2). The data of recent studies are shown to indicate the eff ect of drugs of this group on the indices of central hemodynamics, on the volume of circulating plasma in particular, which can reduce the risk of progression and decompensation of chronic heart failure (CHF). The ability of empaglifl ozin to reduce pulsatility, a marker of increased vascular wall stiff ness, has been demonstrated. Also, SGLT2 inhibitors improve the energy supply of the myocardium and kidney tissue by increasing the concentration of ketone bodies in the blood, which are a more effi cient energy substrate than glucose and fatty acids. A direct pleiotropic eff ect on the myocardium, improvement of diastolic myocardial dysfunction is also not excluded. It is known that SGLT2 inhibitors also reduce cortical hypoxia, decrease intraglomerular hypertension and increase glomerular fi ltration rate, lessen incidence of nephropathy, its severity and rate of progression. Some studies have revealed antioxidant, anti-infl ammatory, antifi brotic eff ect of type 2 sodium glucose cotransporter inhibitors. The use of this group of drugs also leads to a decrease in body weight. This eff ect is more pronounced in combination with other drugs intended for the treatment of obesity. All this makes SGLT2 inhibitors a promising group of drugs that have a large number of pathogenetic points of application in relation to cardiorenal syndrome." @default.
• W3200438894 created "2021-09-27" @default.
• W3200438894 creator A5036222219 @default.
• W3200438894 creator A5049564167 @default.
• W3200438894 creator A5080617864 @default.
• W3200438894 creator A5085445837 @default.
• W3200438894 date "2021-09-15" @default.
• W3200438894 modified "2023-09-27" @default.
• W3200438894 title "Possibilities of cardio- and nephroprotective eff ects of drugs of the SGLT2 inhibitor group" @default.
• W3200438894 cites W1943654307 @default.
• W3200438894 cites W2062527431 @default.
• W3200438894 cites W2085015828 @default.
• W3200438894 cites W2128219379 @default.
• W3200438894 cites W2134304394 @default.
• W3200438894 cites W2134855422 @default.
• W3200438894 cites W2153908199 @default.
• W3200438894 cites W2168630917 @default.
• W3200438894 cites W2168854431 @default.
• W3200438894 cites W2169379549 @default.
• W3200438894 cites W2257723432 @default.
• W3200438894 cites W2412800896 @default.
• W3200438894 cites W2519803668 @default.
• W3200438894 cites W2524330917 @default.
• W3200438894 cites W2563605852 @default.
• W3200438894 cites W2564078202 @default.
• W3200438894 cites W2595201361 @default.
• W3200438894 cites W2623313315 @default.
• W3200438894 cites W2746113086 @default.
• W3200438894 cites W2765097799 @default.
• W3200438894 cites W2790286202 @default.
• W3200438894 cites W2791162071 @default.
• W3200438894 cites W2792832138 @default.
• W3200438894 cites W2793368865 @default.
• W3200438894 cites W2794833267 @default.
• W3200438894 cites W2810892857 @default.
• W3200438894 cites W2870743986 @default.
• W3200438894 cites W2884817413 @default.
• W3200438894 cites W2897621296 @default.
• W3200438894 cites W2911996337 @default.
• W3200438894 cites W2940024069 @default.
• W3200438894 cites W2956803505 @default.
• W3200438894 cites W2961157181 @default.
• W3200438894 cites W2971164718 @default.
• W3200438894 cites W2973090108 @default.
• W3200438894 cites W2974932310 @default.
• W3200438894 cites W2992022999 @default.
• W3200438894 cites W2995061256 @default.
• W3200438894 cites W2998741974 @default.
• W3200438894 cites W2998953838 @default.
• W3200438894 cites W3004108046 @default.
• W3200438894 cites W3005627128 @default.
• W3200438894 cites W3013838418 @default.
• W3200438894 cites W3015945217 @default.
• W3200438894 cites W3020389668 @default.
• W3200438894 cites W3092379111 @default.
• W3200438894 cites W3097524971 @default.
• W3200438894 cites W3102308771 @default.
• W3200438894 cites W3109512796 @default.
• W3200438894 doi "https://doi.org/10.30629/0023-2149-2021-99-3-172-176" @default.
• W3200438894 hasPublicationYear "2021" @default.
• W3200438894 type Work @default.
• W3200438894 sameAs 3200438894 @default.
• W3200438894 citedByCount "0" @default.
• W3200438894 crossrefType "journal-article" @default.
• W3200438894 hasAuthorship W3200438894A5036222219 @default.
• W3200438894 hasAuthorship W3200438894A5049564167 @default.
• W3200438894 hasAuthorship W3200438894A5080617864 @default.
• W3200438894 hasAuthorship W3200438894A5085445837 @default.
• W3200438894 hasConcept C126322002 @default.
• W3200438894 hasConcept C134018914 @default.
• W3200438894 hasConcept C2778198053 @default.
• W3200438894 hasConcept C2778721985 @default.
• W3200438894 hasConcept C2779922275 @default.
• W3200438894 hasConcept C2781184683 @default.
• W3200438894 hasConcept C555293320 @default.
• W3200438894 hasConcept C71924100 @default.
• W3200438894 hasConcept C98274493 @default.
• W3200438894 hasConceptScore W3200438894C126322002 @default.
• W3200438894 hasConceptScore W3200438894C134018914 @default.
• W3200438894 hasConceptScore W3200438894C2778198053 @default.
• W3200438894 hasConceptScore W3200438894C2778721985 @default.
• W3200438894 hasConceptScore W3200438894C2779922275 @default.
• W3200438894 hasConceptScore W3200438894C2781184683 @default.
• W3200438894 hasConceptScore W3200438894C555293320 @default.
• W3200438894 hasConceptScore W3200438894C71924100 @default.
• W3200438894 hasConceptScore W3200438894C98274493 @default.
• W3200438894 hasIssue "3" @default.
• W3200438894 hasLocation W32004388941 @default.
• W3200438894 hasOpenAccess W3200438894 @default.
• W3200438894 hasPrimaryLocation W32004388941 @default.
• W3200438894 hasRelatedWork W1563850031 @default.
• W3200438894 hasRelatedWork W2032111989 @default.
• W3200438894 hasRelatedWork W2038405492 @default.
• W3200438894 hasRelatedWork W2038657938 @default.
• W3200438894 hasRelatedWork W2047956456 @default.
• W3200438894 hasRelatedWork W2096973883 @default.
• W3200438894 hasRelatedWork W2104195310 @default.
• W3200438894 hasRelatedWork W2127085070 @default.

• next