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• W3200467905 abstract "Seseli L. is one of the largest genera of the Apiaceae family widely known for their traditional uses as herbal remedies. In the present study, the methanolic and water extracts of two Seseli species, S. gummiferum and S. transcaucasicum were evaluated for their bioactive contents and biological activities. The total phenolic and flavonoid contents in the extracts ranged from 19.09 to 24.33 mg GAE/g and from 0.45 to10.09 mg RE/g, respectively. Moreover, while narcissin was detected as the most abundant component in the methanolic extract of S. transcaucasicum (261.40 µg/g), chlorogenic acid was identified as the major component in all the other extracts, although a high amount was also present in the methanolic S. transcaucasicum extract (107.48-243.12 µg/g). The total antioxidant capacity was also determined by the phosphomolybdenum assay (0.66-1.18 mM TE/g). Other antioxidant assays such as the radical scavenging assays (DPPH: 5.51-11.45 mg TE/g; ABTS: 43.46-51.91 mg TE/g), reducing assays (CUPRAC: 41.67-53.20 mg TE/g; FRAP: 31.26-34.14 mg TE/g), as well as the metal chelating activity assay (14.38-38.57 mg EDTAE/g) were conducted. All the extracts showed inhibitory potential against the enzyme's amylase (0.12-0.78 mM ACAE/g), acetyl- and butyryl-cholinesterase (0.15-9.71 mg GALAE/g), while only the methanolic extracts acted as inhibitors of tyrosinase (107.15 and 109.37 mg KAE/g) and only the water extract of S. gummiferum displayed anti-glucosidase activity (0.13 mM ACAE/g). Interestingly, the methanolic extracts of both Seseli species showed lower cytotoxicity towards HaCaT cells (IC50: >500 µg/mL), compared to the water extracts (IC50: 267.8 and 321.41 µg/mL). Besides, only the methanolic extracts showed a slight wound healing effect (28.21 and 31.23%). All extracts showed antibacterial action against Staphylococcus lugdunensis (minimum inhibitory and bactericidal concentrations: 0.025-2 mg/mL). S. gummiferum methanolic extract, which exhibited the highest antibacterial potency was found to inhibit adhesion and invasion of S. lugdunensis to HaCaT cells as well. Taken together, this study demonstrated the two Seseli species to harbour interesting bioactive components, in particular polyphenolics and to exhibit several biological properties that could be further investigated for their potential exploitation as healing agents as supported by various traditional medicinal uses." @default.
• W3200467905 created "2021-09-27" @default.
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• W3200467905 date "2021-09-24" @default.
• W3200467905 modified "2023-09-27" @default.
• W3200467905 title "Comprehensive Biological and Chemical Evaluation of Two Seseli Species (S. gummiferum and S. transcaucasicum)" @default.
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• W3200467905 cites W1973733191 @default.
• W3200467905 cites W1974359153 @default.
• W3200467905 cites W1988892650 @default.
• W3200467905 cites W2000456244 @default.
• W3200467905 cites W2001592605 @default.
• W3200467905 cites W2011748373 @default.
• W3200467905 cites W2014042478 @default.
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• W3200467905 cites W2022779719 @default.
• W3200467905 cites W2037195682 @default.
• W3200467905 cites W2049830950 @default.
• W3200467905 cites W2053406276 @default.
• W3200467905 cites W2053631757 @default.
• W3200467905 cites W2055504108 @default.
• W3200467905 cites W2068111329 @default.
• W3200467905 cites W2082209113 @default.
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• W3200467905 cites W2222389861 @default.
• W3200467905 cites W2239408761 @default.
• W3200467905 cites W2250416323 @default.
• W3200467905 cites W2255246778 @default.
• W3200467905 cites W2312567112 @default.
• W3200467905 cites W2312587758 @default.
• W3200467905 cites W2360423750 @default.
• W3200467905 cites W2401546133 @default.
• W3200467905 cites W2411952062 @default.
• W3200467905 cites W2413538473 @default.
• W3200467905 cites W2574143384 @default.
• W3200467905 cites W2575030453 @default.
• W3200467905 cites W2593725575 @default.
• W3200467905 cites W2613335053 @default.
• W3200467905 cites W2735092774 @default.
• W3200467905 cites W2740695644 @default.
• W3200467905 cites W2751097336 @default.
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• W3200467905 cites W2775533952 @default.
• W3200467905 cites W2799993278 @default.
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• W3200467905 cites W2900471081 @default.
• W3200467905 cites W2932151942 @default.
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• W3200467905 cites W2986015386 @default.
• W3200467905 cites W3001243794 @default.
• W3200467905 cites W3005049222 @default.
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• W3200467905 doi "https://doi.org/10.3390/antiox10101510" @default.
• W3200467905 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8532678" @default.
• W3200467905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34679647" @default.
• W3200467905 hasPublicationYear "2021" @default.
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