FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200469092> ?p ?o ?g. }

• W3200469092 endingPage "823" @default.
• W3200469092 startingPage "813" @default.
• W3200469092 abstract "Suboptimal secondary prevention in patients with stroke causes a remaining cardiovascular risk desirable to reduce. We have validated a prognostic model for secondary preventive settings and estimated future cardiovascular risk and theoretical benefit of reaching guideline recommended risk factor targets.The SMART-REACH (Secondary Manifestations of Arterial Disease-Reduction of Atherothrombosis for Continued Health) model for 10-year and lifetime risk of cardiovascular events was applied to 465 patients in the Norwegian Cognitive Impairment After Stroke (Nor-COAST) study, a multicenter observational study with two-year follow-up by linkage to national registries for cardiovascular disease and mortality. The residual risk when reaching recommended targets for blood pressure, low-density lipoprotein cholesterol, smoking cessation and antithrombotics was estimated.In total, 11.2% had a new event. Calibration plots showed adequate agreement between estimated and observed 2-year prognosis (C-statistics 0.63, 95% confidence interval 0.55-0.71). Median estimated 10-year risk of recurrent cardiovascular events was 42% (Interquartile range (IQR) 32-54%) and could be reduced to 32% by optimal guideline-based therapy. The corresponding numbers for lifetime risk were 70% (IQR 63-76%) and 61%. We estimated an overall median gain of 1.4 (IQR 0.2-3.4) event-free life years if guideline targets were met.Secondary prevention was suboptimal and residual risk remains elevated even after optimization according to current guidelines. Considerable interindividual variation in risk exists, with a corresponding variation in benefit from intensification of treatment. The SMART-REACH model can be used to identify patients with the largest benefit from more intensive treatment and follow-up." @default.
• W3200469092 created "2021-09-27" @default.
• W3200469092 creator A5005777285 @default.
• W3200469092 creator A5023548211 @default.
• W3200469092 creator A5027380658 @default.
• W3200469092 creator A5031025442 @default.
• W3200469092 creator A5037721359 @default.
• W3200469092 creator A5047610022 @default.
• W3200469092 creator A5066691215 @default.
• W3200469092 creator A5076873958 @default.
• W3200469092 creator A5077863525 @default.
• W3200469092 date "2021-09-01" @default.
• W3200469092 modified "2023-10-10" @default.
• W3200469092 title "Risk Stratification in Patients with Ischemic Stroke and Residual Cardiovascular Risk with Current Secondary Prevention" @default.
• W3200469092 cites W1480729244 @default.
• W3200469092 cites W2016114416 @default.
• W3200469092 cites W2031756259 @default.
• W3200469092 cites W2033660191 @default.
• W3200469092 cites W2051742459 @default.
• W3200469092 cites W2100089051 @default.
• W3200469092 cites W2101606519 @default.
• W3200469092 cites W2113962387 @default.
• W3200469092 cites W2119673582 @default.
• W3200469092 cites W2129925362 @default.
• W3200469092 cites W2132279603 @default.
• W3200469092 cites W2145246661 @default.
• W3200469092 cites W2153274104 @default.
• W3200469092 cites W2157995113 @default.
• W3200469092 cites W2164089346 @default.
• W3200469092 cites W2164509334 @default.
• W3200469092 cites W2165139489 @default.
• W3200469092 cites W2168365765 @default.
• W3200469092 cites W2168912292 @default.
• W3200469092 cites W2198866495 @default.
• W3200469092 cites W2329499609 @default.
• W3200469092 cites W2346045704 @default.
• W3200469092 cites W2552653484 @default.
• W3200469092 cites W2749380187 @default.
• W3200469092 cites W2776534022 @default.
• W3200469092 cites W2789055647 @default.
• W3200469092 cites W2885111964 @default.
• W3200469092 cites W2893356390 @default.
• W3200469092 cites W2898857410 @default.
• W3200469092 cites W2902641543 @default.
• W3200469092 cites W2955492613 @default.
• W3200469092 cites W2970201384 @default.
• W3200469092 cites W2996480032 @default.
• W3200469092 cites W3017084496 @default.
• W3200469092 cites W3046619605 @default.
• W3200469092 cites W3109880115 @default.
• W3200469092 cites W3131397122 @default.
• W3200469092 doi "https://doi.org/10.2147/clep.s322779" @default.
• W3200469092 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8456548" @default.
• W3200469092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34566434" @default.
• W3200469092 hasPublicationYear "2021" @default.
• W3200469092 type Work @default.
• W3200469092 sameAs 3200469092 @default.
• W3200469092 citedByCount "5" @default.
• W3200469092 countsByYear W32004690922022 @default.
• W3200469092 countsByYear W32004690922023 @default.
• W3200469092 crossrefType "journal-article" @default.
• W3200469092 hasAuthorship W3200469092A5005777285 @default.
• W3200469092 hasAuthorship W3200469092A5023548211 @default.
• W3200469092 hasAuthorship W3200469092A5027380658 @default.
• W3200469092 hasAuthorship W3200469092A5031025442 @default.
• W3200469092 hasAuthorship W3200469092A5037721359 @default.
• W3200469092 hasAuthorship W3200469092A5047610022 @default.
• W3200469092 hasAuthorship W3200469092A5066691215 @default.
• W3200469092 hasAuthorship W3200469092A5076873958 @default.
• W3200469092 hasAuthorship W3200469092A5077863525 @default.
• W3200469092 hasBestOaLocation W32004690921 @default.
• W3200469092 hasConcept C119060515 @default.
• W3200469092 hasConcept C126322002 @default.
• W3200469092 hasConcept C127413603 @default.
• W3200469092 hasConcept C142724271 @default.
• W3200469092 hasConcept C1862650 @default.
• W3200469092 hasConcept C194828623 @default.
• W3200469092 hasConcept C23131810 @default.
• W3200469092 hasConcept C2780182762 @default.
• W3200469092 hasConcept C2780645631 @default.
• W3200469092 hasConcept C44249647 @default.
• W3200469092 hasConcept C71924100 @default.
• W3200469092 hasConcept C78519656 @default.
• W3200469092 hasConcept C84393581 @default.
• W3200469092 hasConceptScore W3200469092C119060515 @default.
• W3200469092 hasConceptScore W3200469092C126322002 @default.
• W3200469092 hasConceptScore W3200469092C127413603 @default.
• W3200469092 hasConceptScore W3200469092C142724271 @default.
• W3200469092 hasConceptScore W3200469092C1862650 @default.
• W3200469092 hasConceptScore W3200469092C194828623 @default.
• W3200469092 hasConceptScore W3200469092C23131810 @default.
• W3200469092 hasConceptScore W3200469092C2780182762 @default.
• W3200469092 hasConceptScore W3200469092C2780645631 @default.
• W3200469092 hasConceptScore W3200469092C44249647 @default.
• W3200469092 hasConceptScore W3200469092C71924100 @default.
• W3200469092 hasConceptScore W3200469092C78519656 @default.
• W3200469092 hasConceptScore W3200469092C84393581 @default.
• W3200469092 hasLocation W32004690921 @default.

• next