Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200496239> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3200496239 endingPage "242" @default.
- W3200496239 startingPage "237" @default.
- W3200496239 abstract "BackgroundDiagnosing tuberculosis (TB) in people living with HIV (PLHIV) is challenging due to atypical clinical and radiological presentation and higher rates of sputum-negative or extrapulmonary disease. Urine LAM is a promising diagnostic biomarker to address these challenges. Yet, AlereLAM, a World Health Organization-recommended point-of-care (POC) test of this kind, remains underutilized. This study aimed to understand perspectives and experiences of those using AlereLAM.MethodsFifteen semi-structured interviews were conducted with clinicians, nurses, program officers, laboratory staff, and patient advocates in Uganda, Kenya, and South Africa. Discussed topics included the approach to diagnosing TB, and experiences, perspectives, and country policy of AlereLAM testing.ResultsThe POC-friendly characteristics of AlereLAM require more work to be realized. Although limited by relatively low sensitivity and specificity, AlereLAM has important value for identifying TB in people with advanced HIV disease, especially when the environment enables constructing confidence in the test. The initial communication about the low performance by global agencies, restrictive eligibility criteria, reliance on CD4+ testing, and lack of advocacy and awareness were noted as reasons for its slow uptake.ConclusionThe work of operationalizing diagnostics, including constructing confidence, is important to consider for policymakers, implementers, and funders when assessing acceptability, feasibility, and scale-up of a diagnostic." @default.
- W3200496239 created "2021-09-27" @default.
- W3200496239 creator A5014759016 @default.
- W3200496239 creator A5040828153 @default.
- W3200496239 date "2021-11-01" @default.
- W3200496239 modified "2023-10-18" @default.
- W3200496239 title "Constructing confidence: User perspectives on AlereLAM testing for tuberculosis" @default.
- W3200496239 cites W1945329129 @default.
- W3200496239 cites W1979290264 @default.
- W3200496239 cites W2016774012 @default.
- W3200496239 cites W2116871266 @default.
- W3200496239 cites W2126731512 @default.
- W3200496239 cites W2213610248 @default.
- W3200496239 cites W2252874986 @default.
- W3200496239 cites W2625405291 @default.
- W3200496239 cites W2755424060 @default.
- W3200496239 cites W2791523882 @default.
- W3200496239 cites W2883578784 @default.
- W3200496239 cites W2980488275 @default.
- W3200496239 cites W2998321752 @default.
- W3200496239 cites W3000609239 @default.
- W3200496239 cites W3143275536 @default.
- W3200496239 cites W37635700 @default.
- W3200496239 cites W4232623787 @default.
- W3200496239 cites W4240151307 @default.
- W3200496239 cites W4377077025 @default.
- W3200496239 cites W4379373326 @default.
- W3200496239 doi "https://doi.org/10.1016/j.ijid.2021.09.018" @default.
- W3200496239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34525399" @default.
- W3200496239 hasPublicationYear "2021" @default.
- W3200496239 type Work @default.
- W3200496239 sameAs 3200496239 @default.
- W3200496239 citedByCount "4" @default.
- W3200496239 countsByYear W32004962392022 @default.
- W3200496239 countsByYear W32004962392023 @default.
- W3200496239 crossrefType "journal-article" @default.
- W3200496239 hasAuthorship W3200496239A5014759016 @default.
- W3200496239 hasAuthorship W3200496239A5040828153 @default.
- W3200496239 hasBestOaLocation W32004962391 @default.
- W3200496239 hasConcept C111472728 @default.
- W3200496239 hasConcept C138885662 @default.
- W3200496239 hasConcept C142724271 @default.
- W3200496239 hasConcept C151730666 @default.
- W3200496239 hasConcept C159110408 @default.
- W3200496239 hasConcept C205649164 @default.
- W3200496239 hasConcept C2777267654 @default.
- W3200496239 hasConcept C2778755073 @default.
- W3200496239 hasConcept C2781069245 @default.
- W3200496239 hasConcept C512399662 @default.
- W3200496239 hasConcept C58640448 @default.
- W3200496239 hasConcept C71924100 @default.
- W3200496239 hasConcept C86803240 @default.
- W3200496239 hasConcept C9354725 @default.
- W3200496239 hasConceptScore W3200496239C111472728 @default.
- W3200496239 hasConceptScore W3200496239C138885662 @default.
- W3200496239 hasConceptScore W3200496239C142724271 @default.
- W3200496239 hasConceptScore W3200496239C151730666 @default.
- W3200496239 hasConceptScore W3200496239C159110408 @default.
- W3200496239 hasConceptScore W3200496239C205649164 @default.
- W3200496239 hasConceptScore W3200496239C2777267654 @default.
- W3200496239 hasConceptScore W3200496239C2778755073 @default.
- W3200496239 hasConceptScore W3200496239C2781069245 @default.
- W3200496239 hasConceptScore W3200496239C512399662 @default.
- W3200496239 hasConceptScore W3200496239C58640448 @default.
- W3200496239 hasConceptScore W3200496239C71924100 @default.
- W3200496239 hasConceptScore W3200496239C86803240 @default.
- W3200496239 hasConceptScore W3200496239C9354725 @default.
- W3200496239 hasFunder F4320307856 @default.
- W3200496239 hasLocation W32004962391 @default.
- W3200496239 hasLocation W32004962392 @default.
- W3200496239 hasLocation W32004962393 @default.
- W3200496239 hasOpenAccess W3200496239 @default.
- W3200496239 hasPrimaryLocation W32004962391 @default.
- W3200496239 hasRelatedWork W2046950915 @default.
- W3200496239 hasRelatedWork W2055670370 @default.
- W3200496239 hasRelatedWork W2097067792 @default.
- W3200496239 hasRelatedWork W2114333609 @default.
- W3200496239 hasRelatedWork W2121457089 @default.
- W3200496239 hasRelatedWork W2134066062 @default.
- W3200496239 hasRelatedWork W2461343464 @default.
- W3200496239 hasRelatedWork W2576082515 @default.
- W3200496239 hasRelatedWork W3040998915 @default.
- W3200496239 hasRelatedWork W4313356762 @default.
- W3200496239 hasVolume "112" @default.
- W3200496239 isParatext "false" @default.
- W3200496239 isRetracted "false" @default.
- W3200496239 magId "3200496239" @default.
- W3200496239 workType "article" @default.