FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200517451> ?p ?o ?g. }

• W3200517451 abstract "The following report is intended to examine the commercial viability of the Diabetic wound monitor using near infrared (NIR) spectroscopy, which is currently under development at Drexel University. The market conditions shall favor the introduction of this technology, as it not only addresses a currently unmet need, but also is expected to appeal to multiple and distinct groups of end users. The overall wound care management market exceeds $20 billion in the U.S., and the global wound care therapies market is growing at an 8% rate annually and forecast to reach $7.3 billion by 2013. With a global yearly incidence of ulcers at 37 million reported cases with more than half comprised of diabetic ulcers, there is a tremendous demand for an accurate assessment of wound healing. The ability to accurately assess wound healing would allow for a change in the course of therapy long before it becomes clinically obvious. The associated cost saving potential is substantial, providing a solid foundation in the pursuit of medical reimbursement for the clinical application of this technology.From a development standpoint, the technology readiness level (TRL) is characterized as having nearly advanced to the midway point. The concept has been proven in animal models and in early human clinical trials to constitute a preliminary proof-of-concept. The first generation device prototype measures absorption and scattering coefficients of tissue in the range of 685 - 830 nm, where differences in absorption reveal changes in tissue oxygenation and blood flow, while differences in scattering correlate to tissue structure and inflammation. In all studies, the performance was stable as both healing and non-healing wounds consistently yielded values of the NIR absorption coefficient μa at the wound center and wound edges greater than values of μa at the control (non-wound) sites. This trend would be expected due to the reduced absorption characteristic of deoxygenated hemoglobin present at the wound site.A failure mode and hazard analysis indicates that the device is headed toward the designation of generally regarded as safe (GRAS). While there are some minor refinements to consider in the engineering design, the element of risk associated with this device shall be considered low. A preliminary review of the regulatory pathway suggests that such a device would only require a 510(k) FDA approval, and a combination of predicate devices has been identified. The primary barrier to entry will comprise the intellectual property rights attainable for the present technology. A small portfolio of pending patents shall provide some protection, and its value shall be further assessed through a comprehensive patent landscape analysis. A preliminary landscape has identified a list of potential competitors and commercial partners provided herein.%%%%M.S., Biomedical Engineering  – Drexel University, 2010" @default.
• W3200517451 created "2021-09-27" @default.
• W3200517451 creator A5051461385 @default.
• W3200517451 date "2021-07-16" @default.
• W3200517451 modified "2023-09-24" @default.
• W3200517451 title "Technology commercialization assessment: near infrared wound healing monitor" @default.
• W3200517451 cites W2004566693 @default.
• W3200517451 cites W2028110617 @default.
• W3200517451 cites W2042338436 @default.
• W3200517451 cites W2082729813 @default.
• W3200517451 cites W2120472250 @default.
• W3200517451 cites W2133340529 @default.
• W3200517451 cites W2336677864 @default.
• W3200517451 doi "https://doi.org/10.17918/etd-3373" @default.
• W3200517451 hasPublicationYear "2021" @default.
• W3200517451 type Work @default.
• W3200517451 sameAs 3200517451 @default.
• W3200517451 citedByCount "0" @default.
• W3200517451 crossrefType "dissertation" @default.
• W3200517451 hasAuthorship W3200517451A5051461385 @default.
• W3200517451 hasConcept C127413603 @default.
• W3200517451 hasConcept C141071460 @default.
• W3200517451 hasConcept C144133560 @default.
• W3200517451 hasConcept C160735492 @default.
• W3200517451 hasConcept C162324750 @default.
• W3200517451 hasConcept C162853370 @default.
• W3200517451 hasConcept C177713679 @default.
• W3200517451 hasConcept C21547014 @default.
• W3200517451 hasConcept C2779703844 @default.
• W3200517451 hasConcept C2780269544 @default.
• W3200517451 hasConcept C2780625559 @default.
• W3200517451 hasConcept C2993807428 @default.
• W3200517451 hasConcept C50522688 @default.
• W3200517451 hasConcept C71924100 @default.
• W3200517451 hasConceptScore W3200517451C127413603 @default.
• W3200517451 hasConceptScore W3200517451C141071460 @default.
• W3200517451 hasConceptScore W3200517451C144133560 @default.
• W3200517451 hasConceptScore W3200517451C160735492 @default.
• W3200517451 hasConceptScore W3200517451C162324750 @default.
• W3200517451 hasConceptScore W3200517451C162853370 @default.
• W3200517451 hasConceptScore W3200517451C177713679 @default.
• W3200517451 hasConceptScore W3200517451C21547014 @default.
• W3200517451 hasConceptScore W3200517451C2779703844 @default.
• W3200517451 hasConceptScore W3200517451C2780269544 @default.
• W3200517451 hasConceptScore W3200517451C2780625559 @default.
• W3200517451 hasConceptScore W3200517451C2993807428 @default.
• W3200517451 hasConceptScore W3200517451C50522688 @default.
• W3200517451 hasConceptScore W3200517451C71924100 @default.
• W3200517451 hasLocation W32005174511 @default.
• W3200517451 hasOpenAccess W3200517451 @default.
• W3200517451 hasPrimaryLocation W32005174511 @default.
• W3200517451 hasRelatedWork W1532941 @default.
• W3200517451 hasRelatedWork W21337508 @default.
• W3200517451 hasRelatedWork W31955605 @default.
• W3200517451 hasRelatedWork W33181037 @default.
• W3200517451 hasRelatedWork W39123141 @default.
• W3200517451 hasRelatedWork W39136481 @default.
• W3200517451 hasRelatedWork W70236958 @default.
• W3200517451 hasRelatedWork W81067294 @default.
• W3200517451 hasRelatedWork W83897809 @default.
• W3200517451 hasRelatedWork W84677739 @default.
• W3200517451 isParatext "false" @default.
• W3200517451 isRetracted "false" @default.
• W3200517451 magId "3200517451" @default.
• W3200517451 workType "dissertation" @default.