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• W3200523369 startingPage "126" @default.
• W3200523369 abstract "Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the formation of intracellular neurofibrillary tangles (NFTs) and extracellular amyloid plaques. Growing evidence has suggested that AD pathogenesis is not only limited to the neuronal compartment but also strongly interacts with immunological processes in the brain. On the other hand, aggregated and misfolded proteins can bind with pattern recognition receptors located on astroglia and microglia and can, in turn, induce an innate immune response, characterized by the release of inflammatory mediators, ultimately playing a role in both the severity and the progression of the disease. It has been reported by genome-wide analysis that several genes which elevate the risk for sporadic AD encode for factors controlling the inflammatory response and glial clearance of misfolded proteins. Obesity and systemic inflammation are examples of external factors which may interfere with the immunological mechanisms of the brain and can induce disease progression. In this review, we discussed the mechanisms and essential role of inflammatory signaling pathways in AD pathogenesis. Indeed, interfering with immune processes and modulation of risk factors may lead to future therapeutic or preventive AD approaches." @default.
• W3200523369 created "2021-09-27" @default.
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• W3200523369 date "2022-01-01" @default.
• W3200523369 modified "2023-09-30" @default.
• W3200523369 title "Neuroinflammatory Signaling in the Pathogenesis of Alzheimer’s Disease" @default.
• W3200523369 cites W10297594 @default.
• W3200523369 cites W1496107582 @default.
• W3200523369 cites W1531336753 @default.
• W3200523369 cites W1540228912 @default.
• W3200523369 cites W1540420763 @default.
• W3200523369 cites W1553210510 @default.
• W3200523369 cites W1581267597 @default.
• W3200523369 cites W1585782290 @default.
• W3200523369 cites W1586876258 @default.
• W3200523369 cites W1595078459 @default.
• W3200523369 cites W1607556721 @default.
• W3200523369 cites W1613451007 @default.
• W3200523369 cites W184676718 @default.
• W3200523369 cites W1937826833 @default.
• W3200523369 cites W1946356711 @default.
• W3200523369 cites W1964117773 @default.
• W3200523369 cites W1965395547 @default.
• W3200523369 cites W1965701476 @default.
• W3200523369 cites W1966081154 @default.
• W3200523369 cites W1966831629 @default.
• W3200523369 cites W1967305755 @default.
• W3200523369 cites W1968014528 @default.
• W3200523369 cites W1968786165 @default.
• W3200523369 cites W1971010029 @default.
• W3200523369 cites W1973892958 @default.
• W3200523369 cites W1974655099 @default.
• W3200523369 cites W1974966491 @default.
• W3200523369 cites W1977657716 @default.
• W3200523369 cites W1977896329 @default.
• W3200523369 cites W1978015084 @default.
• W3200523369 cites W1978567629 @default.
• W3200523369 cites W1978718459 @default.
• W3200523369 cites W1980610697 @default.
• W3200523369 cites W1980883732 @default.
• W3200523369 cites W1981513372 @default.
• W3200523369 cites W1981807851 @default.
• W3200523369 cites W1982456051 @default.
• W3200523369 cites W1984891266 @default.
• W3200523369 cites W1985535790 @default.
• W3200523369 cites W1986611577 @default.
• W3200523369 cites W1988991201 @default.
• W3200523369 cites W1989369404 @default.
• W3200523369 cites W1990350348 @default.
• W3200523369 cites W1991403431 @default.
• W3200523369 cites W1991780813 @default.
• W3200523369 cites W1993016490 @default.
• W3200523369 cites W1993305977 @default.
• W3200523369 cites W1993921740 @default.
• W3200523369 cites W1993976394 @default.
• W3200523369 cites W1993993136 @default.
• W3200523369 cites W1994953714 @default.
• W3200523369 cites W1996024251 @default.
• W3200523369 cites W1997816650 @default.
• W3200523369 cites W1998079087 @default.
• W3200523369 cites W1998981667 @default.
• W3200523369 cites W1999938863 @default.
• W3200523369 cites W2000833088 @default.
• W3200523369 cites W2000917483 @default.
• W3200523369 cites W2001259634 @default.
• W3200523369 cites W2003614844 @default.
• W3200523369 cites W2003674452 @default.
• W3200523369 cites W2004349651 @default.
• W3200523369 cites W2005044790 @default.
• W3200523369 cites W2006035554 @default.
• W3200523369 cites W2008423159 @default.
• W3200523369 cites W2011041653 @default.
• W3200523369 cites W2011239875 @default.
• W3200523369 cites W2011693499 @default.
• W3200523369 cites W2011727503 @default.
• W3200523369 cites W2013100814 @default.
• W3200523369 cites W2013165248 @default.
• W3200523369 cites W2013473257 @default.
• W3200523369 cites W2013597008 @default.
• W3200523369 cites W2015186493 @default.
• W3200523369 cites W2015759485 @default.
• W3200523369 cites W2016000332 @default.
• W3200523369 cites W2016575029 @default.
• W3200523369 cites W2018332716 @default.
• W3200523369 cites W2019148572 @default.
• W3200523369 cites W2026281867 @default.
• W3200523369 cites W2026321461 @default.
• W3200523369 cites W2028240691 @default.

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