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• W3200545366 abstract "In this special publication, we report on a modified synthetic process that results in a stable suspension of Au-PEI nanoparticles, Au-PEI@NIST. Synthesized materials were characterized using an orthogonal approach that included dynamic light scattering (DLS), UV-Vis absorbance (UV-Vis), transmission electron microscopy (TEM), atomic force microscope (AFM), and thermogravimetric analysis (TGA). Very importantly, the end-product in this study demonstrated excellent colloidal stability in multiple aqueous environments including over a wide pH and temperature range of physiological relevance. The product also exhibited long-term storage stability under ambient conditions. Furthermore, the cytotoxicity of Au-PEI@NIST was investigated using the CHO K1 cell line and exhibited dose proportional toxicity, which suggested potential for use as a positive control in nanotoxicology studies. The results and stringent testing regimen point toward an effective and sustainable approach that can serve as a clarified starting point for the development of more complex conjugates for nanomedicine area." @default.
• W3200545366 created "2021-09-27" @default.
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• W3200545366 date "2021-09-16" @default.
• W3200545366 modified "2023-10-16" @default.
• W3200545366 title "Preparation, Characterization, and Biological Activity of Stability-Enhanced Polyethyleneimine-Conjugated Gold Nanoparticles (Au-PEI@NIST) for Biological Application" @default.
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• W3200545366 doi "https://doi.org/10.6028/nist.sp.1200-29" @default.
• W3200545366 hasPublicationYear "2021" @default.
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