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- W3200603654 endingPage "1547" @default.
- W3200603654 startingPage "1539" @default.
- W3200603654 abstract "Influenza vaccine is the mainstay for influenza prevention and elicits immune response and antigen-specific neutralizing antibodies against influenza virus. However, antigenic drift and shift can confer influenza virus to escape from the immune response induced by vaccine, and then reduce the vaccine effectiveness.To improve effect and neutralizing antibody response of vaccine for heterologous influenza virus, a literature review of preclinical and clinical studies published before August 2021 and searched in PubMed, which evaluated vaccine effectiveness improved by adjuvants and administration route.The review showed that adjuvant, including imiquimod, GLA, MF59, and AS03, can improve the effectiveness of influenza vaccines by regulating immune system. Subjects receiving influenza vaccine combined with these adjuvants showed enhanced antibody response against homologous and heterologous virus strains compared to those vaccinated without adjuvant. This review also discussed the role of intradermal vaccination. In contrast to intramuscular vaccination, intradermal vaccination elicited a robust and prolonged antibody response against vaccine strains and drifted virus than intramuscular vaccination." @default.
- W3200603654 created "2021-09-27" @default.
- W3200603654 creator A5073090269 @default.
- W3200603654 creator A5091816086 @default.
- W3200603654 date "2021-10-04" @default.
- W3200603654 modified "2023-10-02" @default.
- W3200603654 title "Approaches in broadening the neutralizing antibody response of the influenza vaccine" @default.
- W3200603654 cites W1543572242 @default.
- W3200603654 cites W1856085589 @default.
- W3200603654 cites W1947912572 @default.
- W3200603654 cites W1964168452 @default.
- W3200603654 cites W1972684176 @default.
- W3200603654 cites W1976088534 @default.
- W3200603654 cites W1976348617 @default.
- W3200603654 cites W1979195886 @default.
- W3200603654 cites W1981274613 @default.
- W3200603654 cites W1983472430 @default.
- W3200603654 cites W1989948011 @default.
- W3200603654 cites W1991083095 @default.
- W3200603654 cites W1993047642 @default.
- W3200603654 cites W1993251220 @default.
- W3200603654 cites W2004433396 @default.
- W3200603654 cites W2011879952 @default.
- W3200603654 cites W2013112188 @default.
- W3200603654 cites W2017076137 @default.
- W3200603654 cites W2019674978 @default.
- W3200603654 cites W2029884055 @default.
- W3200603654 cites W2029915249 @default.
- W3200603654 cites W2035324903 @default.
- W3200603654 cites W2042896356 @default.
- W3200603654 cites W2052338984 @default.
- W3200603654 cites W2053083091 @default.
- W3200603654 cites W2054209117 @default.
- W3200603654 cites W2054222404 @default.
- W3200603654 cites W2064889592 @default.
- W3200603654 cites W2067706898 @default.
- W3200603654 cites W2069699462 @default.
- W3200603654 cites W2070000205 @default.
- W3200603654 cites W2084449201 @default.
- W3200603654 cites W2087770333 @default.
- W3200603654 cites W2089807788 @default.
- W3200603654 cites W2090449499 @default.
- W3200603654 cites W2090715236 @default.
- W3200603654 cites W2092283636 @default.
- W3200603654 cites W2093619091 @default.
- W3200603654 cites W2094933901 @default.
- W3200603654 cites W2102335249 @default.
- W3200603654 cites W2105528332 @default.
- W3200603654 cites W2107367447 @default.
- W3200603654 cites W2110563829 @default.
- W3200603654 cites W2124628291 @default.
- W3200603654 cites W2125068643 @default.
- W3200603654 cites W2126609497 @default.
- W3200603654 cites W2142888237 @default.
- W3200603654 cites W2150633245 @default.
- W3200603654 cites W2156622172 @default.
- W3200603654 cites W2157773036 @default.
- W3200603654 cites W2161000167 @default.
- W3200603654 cites W2163192885 @default.
- W3200603654 cites W2165896641 @default.
- W3200603654 cites W2172200039 @default.
- W3200603654 cites W2261609884 @default.
- W3200603654 cites W2273170792 @default.
- W3200603654 cites W2468627168 @default.
- W3200603654 cites W2529384825 @default.
- W3200603654 cites W2555837754 @default.
- W3200603654 cites W2602546359 @default.
- W3200603654 cites W2603341554 @default.
- W3200603654 cites W2627084677 @default.
- W3200603654 cites W2751694235 @default.
- W3200603654 cites W2766820812 @default.
- W3200603654 cites W2767110860 @default.
- W3200603654 cites W2771874921 @default.
- W3200603654 cites W2774336495 @default.
- W3200603654 cites W2774472361 @default.
- W3200603654 cites W2784183730 @default.
- W3200603654 cites W2786042132 @default.
- W3200603654 cites W2795794761 @default.
- W3200603654 cites W2799573222 @default.
- W3200603654 cites W2804994375 @default.
- W3200603654 cites W2884942225 @default.
- W3200603654 cites W2887722615 @default.
- W3200603654 cites W2889576988 @default.
- W3200603654 cites W2890481427 @default.
- W3200603654 cites W2898556596 @default.
- W3200603654 cites W2904422123 @default.
- W3200603654 cites W2912255049 @default.
- W3200603654 cites W2919184488 @default.
- W3200603654 cites W2921047712 @default.
- W3200603654 cites W2921625605 @default.
- W3200603654 cites W2938678047 @default.
- W3200603654 cites W2945500233 @default.
- W3200603654 cites W2968154944 @default.
- W3200603654 cites W2982405140 @default.
- W3200603654 cites W3016750346 @default.
- W3200603654 cites W3036093056 @default.
- W3200603654 cites W3081381436 @default.
- W3200603654 cites W3112060455 @default.