Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200711164> ?p ?o ?g. }
- W3200711164 endingPage "163" @default.
- W3200711164 startingPage "147" @default.
- W3200711164 abstract "Piperine (PIP) is an alkaloid found primarily in Piper longum, and this natural compound has been shown to exert effects on proliferation and survival against various types of cancer. In particular, PIP has potent inhibitory effects on breast cancer (BC), the most prevalent type of cancer in women worldwide. PIP targets numerous signaling pathways associated with the therapy of BC cells through the following mechanisms: (a) induction of arrest of the cell cycle and apoptosis; (b) alteration of the signaling protein expression; (c) reduction in transcription factors; and (d) inhibition of tumor growth. BC cells have the ability to resist conventional drugs, so one of the strategies is the combination of PIP with other phytochemicals such as paclitaxel, thymoquinone, hesperidin, bee venom, tamoxifen, mitoxantrone, piperlongumin, and curcumin. Nanotechnology-based drug encapsulation systems are currently used to enhance the release of PIP. This includes polymer nanoparticles, carbon nanotubes, and liposomes. In the present review, the chemistry and bioavailability of PIP, its molecular targets in BC, and nanotechnological strategies are discussed. Future research directions are also discussed to further understand this promising natural product." @default.
- W3200711164 created "2021-09-27" @default.
- W3200711164 creator A5025881155 @default.
- W3200711164 creator A5047180027 @default.
- W3200711164 date "2021-09-24" @default.
- W3200711164 modified "2023-10-12" @default.
- W3200711164 title "Piperine for treating breast cancer: A review of molecular mechanisms, combination with anticancer drugs, and nanosystems" @default.
- W3200711164 cites W1276566291 @default.
- W3200711164 cites W147439079 @default.
- W3200711164 cites W1511696522 @default.
- W3200711164 cites W1648100608 @default.
- W3200711164 cites W1789224823 @default.
- W3200711164 cites W1973183794 @default.
- W3200711164 cites W1973539311 @default.
- W3200711164 cites W1977149310 @default.
- W3200711164 cites W1978452405 @default.
- W3200711164 cites W1979099628 @default.
- W3200711164 cites W1982636385 @default.
- W3200711164 cites W1988988697 @default.
- W3200711164 cites W1989270091 @default.
- W3200711164 cites W1992913621 @default.
- W3200711164 cites W1995577291 @default.
- W3200711164 cites W1996834131 @default.
- W3200711164 cites W1998203489 @default.
- W3200711164 cites W2003100469 @default.
- W3200711164 cites W2007649418 @default.
- W3200711164 cites W2009098686 @default.
- W3200711164 cites W2017102177 @default.
- W3200711164 cites W2018537155 @default.
- W3200711164 cites W2023660230 @default.
- W3200711164 cites W2030239647 @default.
- W3200711164 cites W2040950751 @default.
- W3200711164 cites W2054072505 @default.
- W3200711164 cites W2054594589 @default.
- W3200711164 cites W2058463235 @default.
- W3200711164 cites W2060783095 @default.
- W3200711164 cites W2070957155 @default.
- W3200711164 cites W2073934073 @default.
- W3200711164 cites W2074305443 @default.
- W3200711164 cites W2077029264 @default.
- W3200711164 cites W2082762965 @default.
- W3200711164 cites W2087325248 @default.
- W3200711164 cites W2092032160 @default.
- W3200711164 cites W2101129444 @default.
- W3200711164 cites W2103678678 @default.
- W3200711164 cites W2121219172 @default.
- W3200711164 cites W2125540724 @default.
- W3200711164 cites W2131242778 @default.
- W3200711164 cites W2132315586 @default.
- W3200711164 cites W2150026213 @default.
- W3200711164 cites W2161020200 @default.
- W3200711164 cites W2169302611 @default.
- W3200711164 cites W2170408243 @default.
- W3200711164 cites W2321112275 @default.
- W3200711164 cites W2396165980 @default.
- W3200711164 cites W2430048569 @default.
- W3200711164 cites W2498171608 @default.
- W3200711164 cites W2540177567 @default.
- W3200711164 cites W2551154560 @default.
- W3200711164 cites W2612253630 @default.
- W3200711164 cites W2728992026 @default.
- W3200711164 cites W2729738977 @default.
- W3200711164 cites W2751938414 @default.
- W3200711164 cites W2759423335 @default.
- W3200711164 cites W2795346817 @default.
- W3200711164 cites W2809788196 @default.
- W3200711164 cites W2884378719 @default.
- W3200711164 cites W2885843511 @default.
- W3200711164 cites W2893896055 @default.
- W3200711164 cites W2903736348 @default.
- W3200711164 cites W2909113787 @default.
- W3200711164 cites W2915528638 @default.
- W3200711164 cites W2924741552 @default.
- W3200711164 cites W2948525475 @default.
- W3200711164 cites W2953489555 @default.
- W3200711164 cites W2954976451 @default.
- W3200711164 cites W2955664420 @default.
- W3200711164 cites W2998192482 @default.
- W3200711164 cites W3005307039 @default.
- W3200711164 cites W3006574011 @default.
- W3200711164 cites W3016784945 @default.
- W3200711164 cites W3016911840 @default.
- W3200711164 cites W3020251873 @default.
- W3200711164 cites W3026125663 @default.
- W3200711164 cites W3033869790 @default.
- W3200711164 cites W3040612311 @default.
- W3200711164 cites W3044095634 @default.
- W3200711164 cites W3044830147 @default.
- W3200711164 cites W3083864310 @default.
- W3200711164 cites W3097103946 @default.
- W3200711164 cites W4234938795 @default.
- W3200711164 cites W2123002505 @default.
- W3200711164 doi "https://doi.org/10.1002/ptr.7291" @default.
- W3200711164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34559416" @default.
- W3200711164 hasPublicationYear "2021" @default.
- W3200711164 type Work @default.
- W3200711164 sameAs 3200711164 @default.
- W3200711164 citedByCount "14" @default.