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- W3200714059 abstract "Caenorhabditis elegans hermaphrodites first produce a limited number of sperm cells, before their germline switches to oogenesis. Production of progeny then ensues until sperm is depleted. Male production in the self-progeny of hermaphrodites occurs following X-chromosome nondisjunction during gametogenesis, and in the reference strain increases with age of the hermaphrodite parent. To enhance our understanding of the reproductive timecourse in C. elegans, we measured and compared progeny production and male proportion during the early and late reproductive periods of hermaphrodites for 96 wild C. elegans strains. We found that the two traits exhibited natural phenotypic variation with few outliers and a similar reproductive timing pattern as previous reports. Progeny number and male proportion were not correlated in the wild strains, implying that wild strains with a large brood size did not produce males at a higher rate. We also identified loci and candidate genetic variants significantly associated with male-production rate in the late and total reproductive periods. Our results provide an insight into life-history traits in wild C. elegans strains." @default.
- W3200714059 created "2021-09-27" @default.
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- W3200714059 date "2021-09-22" @default.
- W3200714059 modified "2023-10-16" @default.
- W3200714059 title "Natural variation in reproductive timing and X-chromosome non-disjunction in Caenorhabditis elegans" @default.
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- W3200714059 doi "https://doi.org/10.1093/g3journal/jkab327" @default.
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