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- W320071607 abstract "This chapter discusses the effect of bacterial products on interferon production. There are three major classes of interferons: interferons-α, -β, -γ. Interferons-α and –β can often not be separated easily in the murine system and are referred to commonly as interferons-α/β when production in vivo in rodents is described. The list of bacteria that can induce interferons includes both gram-negative and gram-positive bacteria such as S. typhimurium, S. aureus, and Mycobacterium boris strain bacillus Calmette–Guérin (BCG). The chapter presents one technique for inducing interferon-α/β and one technique for inducing interferon-γ using bacteria and/or bacterial products that can be used in animal models systems are described. The interferons are not found normally in the circulation of the animals after infection, and these techniques for induction using bacteria or bacterial products require massive stimulation of the host to be able to detect circulating interferons. It should be noted that because these are infections to which the host is mounting an immune response, many additional cytokines besides the interferons are to be induced by bacteria." @default.
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- W320071607 date "1994-01-01" @default.
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- W320071607 title "Effect of bacterial products on interferon production" @default.
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- W320071607 doi "https://doi.org/10.1016/0076-6879(94)36007-3" @default.
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