FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200739079> ?p ?o ?g. }

• W3200739079 endingPage "158" @default.
• W3200739079 startingPage "147" @default.
• W3200739079 abstract "After harvesting multiple costal cartilages, the local defect disrupts the integrity of the chest wall and may lead to obvious thoracic complications, such as local depression and asymmetry of the bilateral thoracic height. Decellularized materials have been used for tissue reconstruction in clinical surgeries. To apply xenogenic decellularized cartilage in costal cartilage defects, porcine-derived auricular and costal cartilage was tested for characterization, cytotoxicity, macrophage response, and tissue regeneration. Most of the DNA and α-Gal were effectively removed, and the collagen was well preserved after the decellularization process. The glycosaminoglycan (GAG) content decreased significantly compared to that in untreated cartilage. The decellularized auricular cartilage had a larger pore size, more pores, and a higher degradation rate than the decellularized costal cartilage. No apparent nuclei or structural damage was observed in the extracellular matrix. The decellularized auricular cartilage had a higher cell proliferation rate and more prominent immunomodulatory effect than the other groups. Two types of decellularized cartilage, particularly decellularized auricular cartilage, promoted the tissue regeneration in the cartilage defect area, combined with noticeable cartilage morphology and increased chondrogenic gene expression. In our research, the functional components and structure of the extracellular matrix were well preserved after the decellularization process. The decellularized cartilage had better biocompatibility and suitable microenvironment for tissue regeneration in the defect area, suggesting its potential application in cartilage repair during the surgery. STATEMENT OF SIGNIFICANCE: Autologous costal cartilage has been widely used in various surgeries, while the cartilage defects after the harvesting of multiple costal cartilages may cause localized chest wall deformities. Decellularized cartilage is an ideal material that could be produced in the factory and applied in surgeries. In this study, both decellularized costal cartilage and auricular cartilage preserved original structure, functional biocompatibility, immunosuppressive effects, and promoted tissue regeneration in the cartilage defect area." @default.
• W3200739079 created "2021-09-27" @default.
• W3200739079 creator A5037716736 @default.
• W3200739079 creator A5061962128 @default.
• W3200739079 creator A5069490930 @default.
• W3200739079 creator A5076042856 @default.
• W3200739079 creator A5079327832 @default.
• W3200739079 creator A5091058081 @default.
• W3200739079 date "2021-12-01" @default.
• W3200739079 modified "2023-10-06" @default.
• W3200739079 title "The characterization, cytotoxicity, macrophage response and tissue regeneration of decellularized cartilage in costal cartilage defects" @default.
• W3200739079 cites W1480838859 @default.
• W3200739079 cites W1589680178 @default.
• W3200739079 cites W1618744733 @default.
• W3200739079 cites W1972162040 @default.
• W3200739079 cites W1985859986 @default.
• W3200739079 cites W1992724479 @default.
• W3200739079 cites W1999040528 @default.
• W3200739079 cites W2000770184 @default.
• W3200739079 cites W2006601087 @default.
• W3200739079 cites W2014550525 @default.
• W3200739079 cites W2014660712 @default.
• W3200739079 cites W2016436871 @default.
• W3200739079 cites W2016578709 @default.
• W3200739079 cites W2023444166 @default.
• W3200739079 cites W2025590326 @default.
• W3200739079 cites W2034831207 @default.
• W3200739079 cites W2038242891 @default.
• W3200739079 cites W2041401385 @default.
• W3200739079 cites W2045630388 @default.
• W3200739079 cites W2059486645 @default.
• W3200739079 cites W2060551614 @default.
• W3200739079 cites W2062315506 @default.
• W3200739079 cites W2064699790 @default.
• W3200739079 cites W2069978881 @default.
• W3200739079 cites W2077671999 @default.
• W3200739079 cites W2078834918 @default.
• W3200739079 cites W2085403237 @default.
• W3200739079 cites W2118820170 @default.
• W3200739079 cites W2119970428 @default.
• W3200739079 cites W2127513787 @default.
• W3200739079 cites W2130594874 @default.
• W3200739079 cites W2134945818 @default.
• W3200739079 cites W2140380746 @default.
• W3200739079 cites W2148591507 @default.
• W3200739079 cites W2149056364 @default.
• W3200739079 cites W2149913162 @default.
• W3200739079 cites W2217100198 @default.
• W3200739079 cites W2334749926 @default.
• W3200739079 cites W2443767567 @default.
• W3200739079 cites W2521516464 @default.
• W3200739079 cites W2592330143 @default.
• W3200739079 cites W2620361336 @default.
• W3200739079 cites W2775143243 @default.
• W3200739079 cites W2792895473 @default.
• W3200739079 cites W2794682261 @default.
• W3200739079 cites W2795272815 @default.
• W3200739079 cites W2801198579 @default.
• W3200739079 cites W2838827263 @default.
• W3200739079 cites W2927902416 @default.
• W3200739079 cites W2970425348 @default.
• W3200739079 cites W3004733222 @default.
• W3200739079 cites W3016982268 @default.
• W3200739079 cites W3128308879 @default.
• W3200739079 cites W3138422156 @default.
• W3200739079 cites W4251722707 @default.
• W3200739079 doi "https://doi.org/10.1016/j.actbio.2021.09.031" @default.
• W3200739079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34563726" @default.
• W3200739079 hasPublicationYear "2021" @default.
• W3200739079 type Work @default.
• W3200739079 sameAs 3200739079 @default.
• W3200739079 citedByCount "8" @default.
• W3200739079 countsByYear W32007390792022 @default.
• W3200739079 countsByYear W32007390792023 @default.
• W3200739079 crossrefType "journal-article" @default.
• W3200739079 hasAuthorship W3200739079A5037716736 @default.
• W3200739079 hasAuthorship W3200739079A5061962128 @default.
• W3200739079 hasAuthorship W3200739079A5069490930 @default.
• W3200739079 hasAuthorship W3200739079A5076042856 @default.
• W3200739079 hasAuthorship W3200739079A5079327832 @default.
• W3200739079 hasAuthorship W3200739079A5091058081 @default.
• W3200739079 hasConcept C105702510 @default.
• W3200739079 hasConcept C136229726 @default.
• W3200739079 hasConcept C142724271 @default.
• W3200739079 hasConcept C153074725 @default.
• W3200739079 hasConcept C171056886 @default.
• W3200739079 hasConcept C189165786 @default.
• W3200739079 hasConcept C190672674 @default.
• W3200739079 hasConcept C192562407 @default.
• W3200739079 hasConcept C2780550940 @default.
• W3200739079 hasConcept C2781023255 @default.
• W3200739079 hasConcept C49892992 @default.
• W3200739079 hasConcept C71924100 @default.
• W3200739079 hasConcept C86803240 @default.
• W3200739079 hasConcept C95444343 @default.
• W3200739079 hasConceptScore W3200739079C105702510 @default.
• W3200739079 hasConceptScore W3200739079C136229726 @default.
• W3200739079 hasConceptScore W3200739079C142724271 @default.

• next