Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200775797> ?p ?o ?g. }
- W3200775797 endingPage "52" @default.
- W3200775797 startingPage "45" @default.
- W3200775797 abstract "Maternal elevated plasma total homocysteine (tHcy) is involved in the origin of several placenta-related pregnancy complications. The first trimester is the most sensitive period for placentation influenced by maternal and paternal health. The aim is to study associations between periconceptional parental tHcy levels and utero-placental growth trajectories in the first trimester of pregnancy. Pregnant women and their partners were enrolled before 10 weeks of gestation in the Virtual Placenta study as subcohort of the Rotterdam periconception cohort (Predict study). A total of 190 women with a singleton pregnancy, of which 109 conceived naturally and 81 after IVF/ICSI treatment, were included. We measured serial utero-placental vascular volumes (uPVV) and placental volumes (PV) at 7, 9 and 11 weeks of gestation. First-trimester trajectories of PV were also measured in 662 pregnancies from the total Predict study. Comparing all participants of the virtual placenta study, no association between maternal tHcy and uPVV was observed. However, in IVF/ICSI pregnancies sub-analyses showed significantly negative associations between maternal tHcy in the 3rd and 4th quartile and uPVV trajectories (beta: −0.38 (95%CI -0.74 to −0.02) and beta: −0.42 (95% CI -0.78 to −0.05), respectively) with the 1st quartile as reference. Analysis in the total Predict cohort showed similar negative associations for the total study population. Periconceptional high maternal tHcy levels are associated with smaller placental growth trajectories depicted as PV and uPVV in the first trimester of pregnancy. The stronger negative associations with uPVV in IVF/ICSI pregnancies underline the need for further investigation." @default.
- W3200775797 created "2021-09-27" @default.
- W3200775797 creator A5005626266 @default.
- W3200775797 creator A5011337246 @default.
- W3200775797 creator A5011980577 @default.
- W3200775797 creator A5019674343 @default.
- W3200775797 creator A5031351438 @default.
- W3200775797 creator A5045220988 @default.
- W3200775797 creator A5047355338 @default.
- W3200775797 creator A5081052322 @default.
- W3200775797 date "2021-11-01" @default.
- W3200775797 modified "2023-10-18" @default.
- W3200775797 title "Periconceptional maternal and paternal homocysteine levels and early utero-placental (vascular) growth trajectories: The Rotterdam periconception cohort" @default.
- W3200775797 cites W1521598897 @default.
- W3200775797 cites W1750269731 @default.
- W3200775797 cites W1936754821 @default.
- W3200775797 cites W1951825856 @default.
- W3200775797 cites W1967710756 @default.
- W3200775797 cites W1977976250 @default.
- W3200775797 cites W2035953665 @default.
- W3200775797 cites W2047911553 @default.
- W3200775797 cites W2060948205 @default.
- W3200775797 cites W2070863243 @default.
- W3200775797 cites W2088067571 @default.
- W3200775797 cites W2097463714 @default.
- W3200775797 cites W2127382802 @default.
- W3200775797 cites W2141003443 @default.
- W3200775797 cites W2142800783 @default.
- W3200775797 cites W2148698885 @default.
- W3200775797 cites W2151667576 @default.
- W3200775797 cites W2154221817 @default.
- W3200775797 cites W2162866502 @default.
- W3200775797 cites W2281478002 @default.
- W3200775797 cites W2293304001 @default.
- W3200775797 cites W2409597661 @default.
- W3200775797 cites W2427655070 @default.
- W3200775797 cites W2769480306 @default.
- W3200775797 cites W2791043649 @default.
- W3200775797 cites W2899938491 @default.
- W3200775797 cites W2914043773 @default.
- W3200775797 cites W2941921384 @default.
- W3200775797 cites W2947734442 @default.
- W3200775797 cites W2971090174 @default.
- W3200775797 cites W2980246543 @default.
- W3200775797 cites W3093427387 @default.
- W3200775797 cites W3142715830 @default.
- W3200775797 cites W4211051919 @default.
- W3200775797 doi "https://doi.org/10.1016/j.placenta.2021.09.012" @default.
- W3200775797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34560327" @default.
- W3200775797 hasPublicationYear "2021" @default.
- W3200775797 type Work @default.
- W3200775797 sameAs 3200775797 @default.
- W3200775797 citedByCount "4" @default.
- W3200775797 countsByYear W32007757972022 @default.
- W3200775797 countsByYear W32007757972023 @default.
- W3200775797 crossrefType "journal-article" @default.
- W3200775797 hasAuthorship W3200775797A5005626266 @default.
- W3200775797 hasAuthorship W3200775797A5011337246 @default.
- W3200775797 hasAuthorship W3200775797A5011980577 @default.
- W3200775797 hasAuthorship W3200775797A5019674343 @default.
- W3200775797 hasAuthorship W3200775797A5031351438 @default.
- W3200775797 hasAuthorship W3200775797A5045220988 @default.
- W3200775797 hasAuthorship W3200775797A5047355338 @default.
- W3200775797 hasAuthorship W3200775797A5081052322 @default.
- W3200775797 hasBestOaLocation W32007757971 @default.
- W3200775797 hasConcept C126322002 @default.
- W3200775797 hasConcept C131872663 @default.
- W3200775797 hasConcept C172680121 @default.
- W3200775797 hasConcept C201614185 @default.
- W3200775797 hasConcept C201903717 @default.
- W3200775797 hasConcept C2776953305 @default.
- W3200775797 hasConcept C2779234561 @default.
- W3200775797 hasConcept C29456083 @default.
- W3200775797 hasConcept C44249647 @default.
- W3200775797 hasConcept C45167389 @default.
- W3200775797 hasConcept C46973012 @default.
- W3200775797 hasConcept C54355233 @default.
- W3200775797 hasConcept C68443243 @default.
- W3200775797 hasConcept C71924100 @default.
- W3200775797 hasConcept C72563966 @default.
- W3200775797 hasConcept C86803240 @default.
- W3200775797 hasConceptScore W3200775797C126322002 @default.
- W3200775797 hasConceptScore W3200775797C131872663 @default.
- W3200775797 hasConceptScore W3200775797C172680121 @default.
- W3200775797 hasConceptScore W3200775797C201614185 @default.
- W3200775797 hasConceptScore W3200775797C201903717 @default.
- W3200775797 hasConceptScore W3200775797C2776953305 @default.
- W3200775797 hasConceptScore W3200775797C2779234561 @default.
- W3200775797 hasConceptScore W3200775797C29456083 @default.
- W3200775797 hasConceptScore W3200775797C44249647 @default.
- W3200775797 hasConceptScore W3200775797C45167389 @default.
- W3200775797 hasConceptScore W3200775797C46973012 @default.
- W3200775797 hasConceptScore W3200775797C54355233 @default.
- W3200775797 hasConceptScore W3200775797C68443243 @default.
- W3200775797 hasConceptScore W3200775797C71924100 @default.
- W3200775797 hasConceptScore W3200775797C72563966 @default.
- W3200775797 hasConceptScore W3200775797C86803240 @default.
- W3200775797 hasFunder F4320321687 @default.