Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200782513> ?p ?o ?g. }
- W3200782513 endingPage "693" @default.
- W3200782513 startingPage "683" @default.
- W3200782513 abstract "Radiation therapy is traditionally used for the local control of tumour growth, but recent studies suggest that radiation therapy can have immunomodulatory properties that can be applied in combination therapy with immunotherapeutic agents. The paradigm of using radiation therapy for immunomodulation in cancer treatment is a rapidly progressing field, with multiple ongoing clinical trials exploring its use in combination with immune checkpoint blockades to induce an abscopal effect. Permutations of radiation therapy regimens, including variations in radiation dosing, radiation planning parameters and radiation modality, are being tested with varying degrees of success. The relative biological effectiveness was a concept introduced in the early days of radiation biology that allows the comparison of local tumour control across various radiation modalities and energies. Similarly, there remains a need for a new concept of comparing the immunological effectiveness of various radiation modalities. In this review, we will provide an overview of immunobiological models for preclinical and clinical monitoring of radiation therapy regimens and introduce the concept of relative immunological effectiveness to compare and screen for immune-activating functions of these regimens." @default.
- W3200782513 created "2021-09-27" @default.
- W3200782513 creator A5022535440 @default.
- W3200782513 creator A5034361964 @default.
- W3200782513 creator A5055510159 @default.
- W3200782513 creator A5070908847 @default.
- W3200782513 date "2021-11-01" @default.
- W3200782513 modified "2023-10-16" @default.
- W3200782513 title "Repurposing Radiation Therapy for Immuno-oncology" @default.
- W3200782513 cites W1536264784 @default.
- W3200782513 cites W1792045378 @default.
- W3200782513 cites W1966217032 @default.
- W3200782513 cites W1979811833 @default.
- W3200782513 cites W2005391728 @default.
- W3200782513 cites W2026861011 @default.
- W3200782513 cites W2053703796 @default.
- W3200782513 cites W2060794677 @default.
- W3200782513 cites W2088250735 @default.
- W3200782513 cites W2095327320 @default.
- W3200782513 cites W2096122418 @default.
- W3200782513 cites W2107241007 @default.
- W3200782513 cites W2108789863 @default.
- W3200782513 cites W2117280704 @default.
- W3200782513 cites W2132429759 @default.
- W3200782513 cites W2132564070 @default.
- W3200782513 cites W2147210428 @default.
- W3200782513 cites W2150293352 @default.
- W3200782513 cites W2159707944 @default.
- W3200782513 cites W2159744630 @default.
- W3200782513 cites W2212687827 @default.
- W3200782513 cites W2231752536 @default.
- W3200782513 cites W2288738065 @default.
- W3200782513 cites W2521503673 @default.
- W3200782513 cites W2536769127 @default.
- W3200782513 cites W2551911481 @default.
- W3200782513 cites W2592120828 @default.
- W3200782513 cites W2618641368 @default.
- W3200782513 cites W2761351587 @default.
- W3200782513 cites W2761681010 @default.
- W3200782513 cites W2763053634 @default.
- W3200782513 cites W2768550912 @default.
- W3200782513 cites W2768557781 @default.
- W3200782513 cites W2768987490 @default.
- W3200782513 cites W2799371485 @default.
- W3200782513 cites W2802116219 @default.
- W3200782513 cites W2802698341 @default.
- W3200782513 cites W2886568597 @default.
- W3200782513 cites W2893824814 @default.
- W3200782513 cites W2897100571 @default.
- W3200782513 cites W2905447079 @default.
- W3200782513 cites W2943031211 @default.
- W3200782513 cites W2956407134 @default.
- W3200782513 cites W2969307460 @default.
- W3200782513 cites W2971006194 @default.
- W3200782513 cites W2972747302 @default.
- W3200782513 cites W2989811984 @default.
- W3200782513 cites W2991169192 @default.
- W3200782513 cites W3002591556 @default.
- W3200782513 cites W3005411249 @default.
- W3200782513 cites W3005779097 @default.
- W3200782513 cites W3011009916 @default.
- W3200782513 cites W3013168292 @default.
- W3200782513 cites W3016834067 @default.
- W3200782513 cites W3021538489 @default.
- W3200782513 cites W3031763493 @default.
- W3200782513 cites W3037929239 @default.
- W3200782513 cites W3042043324 @default.
- W3200782513 cites W3048123020 @default.
- W3200782513 cites W3084002423 @default.
- W3200782513 cites W3131120802 @default.
- W3200782513 cites W3135350757 @default.
- W3200782513 cites W3147500389 @default.
- W3200782513 cites W3148592396 @default.
- W3200782513 cites W3161451006 @default.
- W3200782513 cites W3175267761 @default.
- W3200782513 cites W3176460341 @default.
- W3200782513 doi "https://doi.org/10.1016/j.clon.2021.08.015" @default.
- W3200782513 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34535358" @default.
- W3200782513 hasPublicationYear "2021" @default.
- W3200782513 type Work @default.
- W3200782513 sameAs 3200782513 @default.
- W3200782513 citedByCount "5" @default.
- W3200782513 countsByYear W32007825132021 @default.
- W3200782513 countsByYear W32007825132022 @default.
- W3200782513 countsByYear W32007825132023 @default.
- W3200782513 crossrefType "journal-article" @default.
- W3200782513 hasAuthorship W3200782513A5022535440 @default.
- W3200782513 hasAuthorship W3200782513A5034361964 @default.
- W3200782513 hasAuthorship W3200782513A5055510159 @default.
- W3200782513 hasAuthorship W3200782513A5070908847 @default.
- W3200782513 hasBestOaLocation W32007825131 @default.
- W3200782513 hasConcept C125118446 @default.
- W3200782513 hasConcept C126322002 @default.
- W3200782513 hasConcept C143998085 @default.
- W3200782513 hasConcept C144024400 @default.
- W3200782513 hasConcept C18903297 @default.
- W3200782513 hasConcept C19527891 @default.
- W3200782513 hasConcept C203014093 @default.