FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3200926265> ?p ?o ?g. }

• W3200926265 endingPage "835" @default.
• W3200926265 startingPage "821" @default.
• W3200926265 abstract "Gene deletion by the Cre-Loxp system has facilitated functional studies of many critical genes in mice, offering important insights and allowing deeper understanding on the mechanisms underlying organ development and diseases, such as heart development and diseases. In this study, we generated a Myh6-Cre knockin mouse model by inserting the IRES-Cre-wpre-polyA cassette between the translational stop codon and the 3' untranslated region of the endogenous Myh6 gene. By crossing knockin mice with the Rosa26 reporter lines, we found that Myh6-Cre targeted cardiomyocytes at the embryonic and postnatal stages. In addition, we were able to inactivate the desmosome gene Desmoplakin (Dsp) by breeding Myh6-Cre mice with a conditional Dspflox knockout mouse line, which resulted in embryonic lethality during the mid-term pregnancy. These results suggest that the new Myh6-Cre mouse line can serve as a robust tool to dissect the distinct roles of genes involved in heart development and function." @default.
• W3200926265 created "2021-09-27" @default.
• W3200926265 creator A5003360183 @default.
• W3200926265 creator A5003759585 @default.
• W3200926265 creator A5018311153 @default.
• W3200926265 creator A5039059766 @default.
• W3200926265 creator A5063502070 @default.
• W3200926265 creator A5067863878 @default.
• W3200926265 creator A5076381718 @default.
• W3200926265 creator A5087200932 @default.
• W3200926265 date "2021-09-20" @default.
• W3200926265 modified "2023-10-16" @default.
• W3200926265 title "Generation and characterization of a Myh6-driven Cre knockin mouse line" @default.
• W3200926265 cites W1973557736 @default.
• W3200926265 cites W2020594690 @default.
• W3200926265 cites W2027264255 @default.
• W3200926265 cites W2036299862 @default.
• W3200926265 cites W2038425676 @default.
• W3200926265 cites W2038629624 @default.
• W3200926265 cites W2050203819 @default.
• W3200926265 cites W2063519499 @default.
• W3200926265 cites W2069113393 @default.
• W3200926265 cites W2092277680 @default.
• W3200926265 cites W2092381049 @default.
• W3200926265 cites W2099037109 @default.
• W3200926265 cites W2100058654 @default.
• W3200926265 cites W2104135721 @default.
• W3200926265 cites W2116160693 @default.
• W3200926265 cites W2119314695 @default.
• W3200926265 cites W2127423627 @default.
• W3200926265 cites W2131736369 @default.
• W3200926265 cites W2133430161 @default.
• W3200926265 cites W2134208169 @default.
• W3200926265 cites W2137654131 @default.
• W3200926265 cites W2138839726 @default.
• W3200926265 cites W2149292131 @default.
• W3200926265 cites W2154201149 @default.
• W3200926265 cites W2154992092 @default.
• W3200926265 cites W2158830336 @default.
• W3200926265 cites W2345376732 @default.
• W3200926265 cites W2401529445 @default.
• W3200926265 cites W2508817558 @default.
• W3200926265 cites W2941530073 @default.
• W3200926265 cites W2941565518 @default.
• W3200926265 cites W2944923640 @default.
• W3200926265 cites W2953103409 @default.
• W3200926265 doi "https://doi.org/10.1007/s11248-021-00285-4" @default.
• W3200926265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8580938" @default.
• W3200926265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34542814" @default.
• W3200926265 hasPublicationYear "2021" @default.
• W3200926265 type Work @default.
• W3200926265 sameAs 3200926265 @default.
• W3200926265 citedByCount "7" @default.
• W3200926265 countsByYear W32009262652022 @default.
• W3200926265 countsByYear W32009262652023 @default.
• W3200926265 crossrefType "journal-article" @default.
• W3200926265 hasAuthorship W3200926265A5003360183 @default.
• W3200926265 hasAuthorship W3200926265A5003759585 @default.
• W3200926265 hasAuthorship W3200926265A5018311153 @default.
• W3200926265 hasAuthorship W3200926265A5039059766 @default.
• W3200926265 hasAuthorship W3200926265A5063502070 @default.
• W3200926265 hasAuthorship W3200926265A5067863878 @default.
• W3200926265 hasAuthorship W3200926265A5076381718 @default.
• W3200926265 hasAuthorship W3200926265A5087200932 @default.
• W3200926265 hasBestOaLocation W32009262651 @default.
• W3200926265 hasConcept C104317684 @default.
• W3200926265 hasConcept C111829913 @default.
• W3200926265 hasConcept C145103041 @default.
• W3200926265 hasConcept C53345823 @default.
• W3200926265 hasConcept C54355233 @default.
• W3200926265 hasConcept C62425271 @default.
• W3200926265 hasConcept C74581901 @default.
• W3200926265 hasConcept C77957584 @default.
• W3200926265 hasConcept C83482732 @default.
• W3200926265 hasConcept C86803240 @default.
• W3200926265 hasConcept C95444343 @default.
• W3200926265 hasConceptScore W3200926265C104317684 @default.
• W3200926265 hasConceptScore W3200926265C111829913 @default.
• W3200926265 hasConceptScore W3200926265C145103041 @default.
• W3200926265 hasConceptScore W3200926265C53345823 @default.
• W3200926265 hasConceptScore W3200926265C54355233 @default.
• W3200926265 hasConceptScore W3200926265C62425271 @default.
• W3200926265 hasConceptScore W3200926265C74581901 @default.
• W3200926265 hasConceptScore W3200926265C77957584 @default.
• W3200926265 hasConceptScore W3200926265C83482732 @default.
• W3200926265 hasConceptScore W3200926265C86803240 @default.
• W3200926265 hasConceptScore W3200926265C95444343 @default.
• W3200926265 hasIssue "6" @default.
• W3200926265 hasLocation W32009262651 @default.
• W3200926265 hasLocation W32009262652 @default.
• W3200926265 hasLocation W32009262653 @default.
• W3200926265 hasOpenAccess W3200926265 @default.
• W3200926265 hasPrimaryLocation W32009262651 @default.
• W3200926265 hasRelatedWork W1992096920 @default.
• W3200926265 hasRelatedWork W2012099407 @default.
• W3200926265 hasRelatedWork W2068897740 @default.
• W3200926265 hasRelatedWork W2120328735 @default.
• W3200926265 hasRelatedWork W2388148973 @default.

• next