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- W3200943883 abstract "The R6/2 murine model of Huntington's disease (HD) is extensively used in HD research. The current study replicates and extends previous work assessing the impact of housing R6/2 mice with healthy wild-type (WT) littermates on disease progression. The current study extends the previous finding by including male cohorts and the use of a standard diet and water regimen, as opposed to the enhanced diet used in the previous study. This study found that the inclusion of healthy wild-type (WT) littermates, alone, improved survivabilty in R6/2 mice, but did not have a significant impact on weight loss." @default.
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- W3200943883 date "2021-09-07" @default.
- W3200943883 modified "2023-09-27" @default.
- W3200943883 title "Housing R6/2 Mice with Wild-Type Littermates Increases Lifespan" @default.
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- W3200943883 doi "https://doi.org/10.3233/jhd-210474" @default.
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