FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201009631> ?p ?o ?g. }

• W3201009631 endingPage "102" @default.
• W3201009631 startingPage "95" @default.
• W3201009631 abstract "Patients with major depressive disorder (MDD) frequently retain cognitive disturbances after recovery from mood symptoms. We investigated the relationship between early response of mood symptoms and/or remission, and residual cognitive disturbances after 6 months of antidepressant treatment.518 patients with MDD were followed up for 6 months after antidepressant treatment initiation (first-line or switch from a previous drug). Subjective and objective cognitive disturbances were assessed by the Perceived Deficits Questionnaire - Depression (PDQ-D) and digit symbol substitution test (DSST), respectively. Depressive symptoms, as well as remission and early response to treatment, were assessed using the Montgomery-Asberg Depression Rating Scale (MADRS). Multivariable linear and logistic regression models were used to adjust for confounders.Early response of depressive mood (≥50% reduction in MADRS score at month 1) was related with fewer residual subjective cognitive symptoms, as evaluated by the PDQ-D at month 6 (p<0.001). Likewise, early remission status at month 2 was inversely associated with PDQ-D scores at month 6 (p<0.001). Among patients with baseline DSST scores of ≥1 standard deviation below the norm, early response/remission was associated with better performance on the DSST at month 6 (p<0.05).The cohort may not be representative of the general MDD patient population, and the possible influence of concomitant medications was not evaluated.These findings suggest that early improvements in depressive symptoms predict better cognitive outcomes in patients with MDD. Grouping of patients by mood and cognition status in early stages of antidepressant treatments may facilitate efforts to improve long-term functional outcomes." @default.
• W3201009631 created "2021-09-27" @default.
• W3201009631 creator A5000541947 @default.
• W3201009631 creator A5002900306 @default.
• W3201009631 creator A5024700132 @default.
• W3201009631 creator A5033551304 @default.
• W3201009631 creator A5043014091 @default.
• W3201009631 creator A5050158822 @default.
• W3201009631 creator A5083970384 @default.
• W3201009631 creator A5087765303 @default.
• W3201009631 date "2022-01-01" @default.
• W3201009631 modified "2023-09-25" @default.
• W3201009631 title "Prediction of residual cognitive disturbances by early response of depressive symptoms to antidepressant treatments in patients with major depressive disorder" @default.
• W3201009631 cites W1890874870 @default.
• W3201009631 cites W1964130542 @default.
• W3201009631 cites W1973428015 @default.
• W3201009631 cites W1978034197 @default.
• W3201009631 cites W1978489780 @default.
• W3201009631 cites W1986936647 @default.
• W3201009631 cites W1990166011 @default.
• W3201009631 cites W1993810702 @default.
• W3201009631 cites W2019386884 @default.
• W3201009631 cites W2026328830 @default.
• W3201009631 cites W2030045599 @default.
• W3201009631 cites W2031466998 @default.
• W3201009631 cites W2037227674 @default.
• W3201009631 cites W2081630416 @default.
• W3201009631 cites W2085295454 @default.
• W3201009631 cites W2086317781 @default.
• W3201009631 cites W2105863382 @default.
• W3201009631 cites W2109309568 @default.
• W3201009631 cites W2118122428 @default.
• W3201009631 cites W2131823335 @default.
• W3201009631 cites W2132699864 @default.
• W3201009631 cites W2150037324 @default.
• W3201009631 cites W2159662907 @default.
• W3201009631 cites W2171043804 @default.
• W3201009631 cites W2695324929 @default.
• W3201009631 cites W2742364650 @default.
• W3201009631 cites W2783590509 @default.
• W3201009631 cites W2811495424 @default.
• W3201009631 cites W2885302911 @default.
• W3201009631 cites W2888254436 @default.
• W3201009631 cites W2889140718 @default.
• W3201009631 cites W2898124695 @default.
• W3201009631 cites W2902380427 @default.
• W3201009631 cites W2904168485 @default.
• W3201009631 cites W2917228575 @default.
• W3201009631 cites W2954928390 @default.
• W3201009631 cites W2964831565 @default.
• W3201009631 cites W2968016090 @default.
• W3201009631 cites W2968391207 @default.
• W3201009631 cites W3094716532 @default.
• W3201009631 cites W3144152466 @default.
• W3201009631 cites W3176676931 @default.
• W3201009631 doi "https://doi.org/10.1016/j.jad.2021.09.025" @default.
• W3201009631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34597893" @default.
• W3201009631 hasPublicationYear "2022" @default.
• W3201009631 type Work @default.
• W3201009631 sameAs 3201009631 @default.
• W3201009631 citedByCount "4" @default.
• W3201009631 countsByYear W32010096312022 @default.
• W3201009631 countsByYear W32010096312023 @default.
• W3201009631 crossrefType "journal-article" @default.
• W3201009631 hasAuthorship W3201009631A5000541947 @default.
• W3201009631 hasAuthorship W3201009631A5002900306 @default.
• W3201009631 hasAuthorship W3201009631A5024700132 @default.
• W3201009631 hasAuthorship W3201009631A5033551304 @default.
• W3201009631 hasAuthorship W3201009631A5043014091 @default.
• W3201009631 hasAuthorship W3201009631A5050158822 @default.
• W3201009631 hasAuthorship W3201009631A5083970384 @default.
• W3201009631 hasAuthorship W3201009631A5087765303 @default.
• W3201009631 hasBestOaLocation W32010096311 @default.
• W3201009631 hasConcept C118552586 @default.
• W3201009631 hasConcept C126322002 @default.
• W3201009631 hasConcept C138496976 @default.
• W3201009631 hasConcept C139719470 @default.
• W3201009631 hasConcept C142724271 @default.
• W3201009631 hasConcept C15744967 @default.
• W3201009631 hasConcept C162324750 @default.
• W3201009631 hasConcept C169900460 @default.
• W3201009631 hasConcept C185711340 @default.
• W3201009631 hasConcept C204787440 @default.
• W3201009631 hasConcept C27081682 @default.
• W3201009631 hasConcept C2775972397 @default.
• W3201009631 hasConcept C2776867660 @default.
• W3201009631 hasConcept C2777965283 @default.
• W3201009631 hasConcept C2779177272 @default.
• W3201009631 hasConcept C2780051608 @default.
• W3201009631 hasConcept C2780733359 @default.
• W3201009631 hasConcept C2781210005 @default.
• W3201009631 hasConcept C558461103 @default.
• W3201009631 hasConcept C70410870 @default.
• W3201009631 hasConcept C71924100 @default.
• W3201009631 hasConcept C72563966 @default.
• W3201009631 hasConcept C83849319 @default.
• W3201009631 hasConceptScore W3201009631C118552586 @default.
• W3201009631 hasConceptScore W3201009631C126322002 @default.

• next