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- W3201022015 abstract "A DO-UniBIC gene screening method was proposed. Firstly, Disease Ontology (DO) analysis was used to screen out breast cancer related genes from differentially expressed genes, and then UniBIC algorithm was used to find all gene clusters with the same changing trend based on the longest common subsequence. In addition, an eight-genes prognostic model was constructed to assess the prognostic risk of breast cancer patients. The prognostic analysis of the candidate gene set yielded eight genes that significantly related to the prognosis. The eight genes were ACSL1, CD24, EMP1, JPH3, CAMK4, JUN, S100B and TP53AIP1. Among them, ACSL1 was a new breast cancer potentially related gene screened by the DO-UniBIC method. More comprehensive cancer-related genes can be screened based on the DO-UniBIC method, which can be used as the candidate gene set for the prognostic analysis." @default.
- W3201022015 created "2021-09-27" @default.
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- W3201022015 date "2021-01-01" @default.
- W3201022015 modified "2023-09-22" @default.
- W3201022015 title "Prognosis Analysis of Breast Cancer Based on DO-UniBIC Gene Screening Method" @default.
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- W3201022015 doi "https://doi.org/10.1007/978-3-030-87571-8_19" @default.
- W3201022015 hasPublicationYear "2021" @default.
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