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• W3201036314 endingPage "4637" @default.
• W3201036314 startingPage "4637" @default.
• W3201036314 abstract "Lung-resident mesenchymal stem cells (LR-MSCs) are non-hematopoietic multipotent stromal cells that predominately reside adventitial within lung blood vessels. Based on their self-renewal and differentiation properties, LR-MSCs turned out to be important regulators of normal lung homeostasis. LR-MSCs exert beneficial effects mainly by local secretion of various growth factors and cytokines that in turn foster pulmonary regeneration including suppression of inflammation. At the same time, MSCs derived from various tissues of origins represent the first choice of cells for cell-based therapeutic applications in clinical medicine. Particularly for various acute as well as chronic lung diseases, the therapeutic applications of exogenous MSCs were shown to mediate beneficial effects, hereby improving lung function and survival. In contrast, endogenous MSCs of normal lungs seem not to be sufficient for lung tissue protection or repair following a pathological trigger; LR-MSCs could even contribute to initiation and/or progression of lung diseases, particularly lung cancer because of their inherent tropism to migrate towards primary tumors and metastatic sites. However, the role of endogenous LR-MSCs to be multipotent tumor-associated (stromal) precursors remains to be unraveled. Here, we summarize the recent knowledge how ‘cancer-educated’ LR-MSCs impact on lung cancer with a focus on mesenchymal stem cell fates." @default.
• W3201036314 created "2021-09-27" @default.
• W3201036314 creator A5003692129 @default.
• W3201036314 creator A5023206608 @default.
• W3201036314 date "2021-09-16" @default.
• W3201036314 modified "2023-10-16" @default.
• W3201036314 title "Lung-Resident Mesenchymal Stem Cell Fates within Lung Cancer" @default.
• W3201036314 cites W1660392447 @default.
• W3201036314 cites W1963759977 @default.
• W3201036314 cites W1979704965 @default.
• W3201036314 cites W1980607051 @default.
• W3201036314 cites W1987348882 @default.
• W3201036314 cites W1994553956 @default.
• W3201036314 cites W1999439792 @default.
• W3201036314 cites W2009230738 @default.
• W3201036314 cites W2015719752 @default.
• W3201036314 cites W2020960914 @default.
• W3201036314 cites W2025371271 @default.
• W3201036314 cites W2032995169 @default.
• W3201036314 cites W2049034302 @default.
• W3201036314 cites W2050025717 @default.
• W3201036314 cites W2073290778 @default.
• W3201036314 cites W2079953735 @default.
• W3201036314 cites W2080940399 @default.
• W3201036314 cites W2081163339 @default.
• W3201036314 cites W2083370714 @default.
• W3201036314 cites W2086929403 @default.
• W3201036314 cites W2095443864 @default.
• W3201036314 cites W2108444276 @default.
• W3201036314 cites W2110957241 @default.
• W3201036314 cites W2116795951 @default.
• W3201036314 cites W2117692326 @default.
• W3201036314 cites W2117814597 @default.
• W3201036314 cites W2132966617 @default.
• W3201036314 cites W2140088548 @default.
• W3201036314 cites W2158688408 @default.
• W3201036314 cites W2165845169 @default.
• W3201036314 cites W2166672922 @default.
• W3201036314 cites W2171062983 @default.
• W3201036314 cites W2228918368 @default.
• W3201036314 cites W2261243847 @default.
• W3201036314 cites W2301064553 @default.
• W3201036314 cites W2396213597 @default.
• W3201036314 cites W2410407699 @default.
• W3201036314 cites W2462641325 @default.
• W3201036314 cites W2464290802 @default.
• W3201036314 cites W2508069933 @default.
• W3201036314 cites W2512899508 @default.
• W3201036314 cites W2529808715 @default.
• W3201036314 cites W2542779249 @default.
• W3201036314 cites W2547358231 @default.
• W3201036314 cites W2560471616 @default.
• W3201036314 cites W2573812177 @default.
• W3201036314 cites W2581321997 @default.
• W3201036314 cites W2607334895 @default.
• W3201036314 cites W2622762135 @default.
• W3201036314 cites W2649656222 @default.
• W3201036314 cites W2741205066 @default.
• W3201036314 cites W2751524454 @default.
• W3201036314 cites W2758927689 @default.
• W3201036314 cites W2769263776 @default.
• W3201036314 cites W2769635882 @default.
• W3201036314 cites W2781482652 @default.
• W3201036314 cites W2782953299 @default.
• W3201036314 cites W2783142330 @default.
• W3201036314 cites W2784371446 @default.
• W3201036314 cites W2785291766 @default.
• W3201036314 cites W2787794088 @default.
• W3201036314 cites W2788451639 @default.
• W3201036314 cites W2792755886 @default.
• W3201036314 cites W2794280940 @default.
• W3201036314 cites W2795047704 @default.
• W3201036314 cites W2795067181 @default.
• W3201036314 cites W2797930709 @default.
• W3201036314 cites W2799838493 @default.
• W3201036314 cites W2803937430 @default.
• W3201036314 cites W2865352686 @default.
• W3201036314 cites W2886211145 @default.
• W3201036314 cites W2891616394 @default.
• W3201036314 cites W2904211489 @default.
• W3201036314 cites W2911671599 @default.
• W3201036314 cites W2921770849 @default.
• W3201036314 cites W2922323050 @default.
• W3201036314 cites W2925537042 @default.
• W3201036314 cites W2937778492 @default.
• W3201036314 cites W2938403043 @default.
• W3201036314 cites W2940324041 @default.
• W3201036314 cites W2943233832 @default.
• W3201036314 cites W2949675365 @default.
• W3201036314 cites W2955317964 @default.
• W3201036314 cites W2962332256 @default.
• W3201036314 cites W2964069940 @default.
• W3201036314 cites W2968047484 @default.
• W3201036314 cites W2981000288 @default.
• W3201036314 cites W2982287559 @default.
• W3201036314 cites W2986235083 @default.
• W3201036314 cites W2990025971 @default.
• W3201036314 cites W2993902820 @default.

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