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- W3201043609 abstract "The aim of our study was to evaluate the role of polymorphism genes rs1799998 of the CYP11B2 and rs198389 NPPB in patients with chronic heart failure (CHF). In patients with CHF 152 Uzbek nationality have been studied the alleles and genotypes genes rs1799998 CYP11B2 and rs198389 NPPB. T / T genotype of the polymorphic locus rs1799998 of the CYP11B2 gene plays a significant role in the formation of CHF and is a risk factor for the development of a severe course of the disease. The difference in the distribution of the NPPB gene (rs198389) frequency of the unfavorable C allele between the group of CHF patients and the control group was characterized by its clear increase among patients by 1.4 times and was accompanied an increase in the unfavorable genotypes T / C and C / C compared to those in the control group by 1.2 and 1.5 times." @default.
- W3201043609 created "2021-09-27" @default.
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- W3201043609 date "2021-01-01" @default.
- W3201043609 modified "2023-09-23" @default.
- W3201043609 title "Study of the Gene rs1799998 of the CYP11B2 and rs198389 NPPB Polymorphism with Chronic Heart Failure" @default.
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