FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201064305> ?p ?o ?g. }

• W3201064305 endingPage "110682" @default.
• W3201064305 startingPage "110682" @default.
• W3201064305 abstract "Recognition of low grade or asymptomatic systemic diseases suggests prevention of the worst, yet has been proven challenging ever since. Biomarker-based liquid biopsy has emerged in recent years as a practical platform for the assessment of systemic diseases yet, technical realizations were mainly focused on cancer, faced challenges in accuracy at early stage and are lacking provision of sufficient evidence of disease. In particular in cell-based cancer liquid biopsy, obstacles are rarity and heterogeneity of circulating tumor and tumor-associated rare cells. Evidence is mounting about an entire spectrum of distinct circulating rare cell types that denotes the systemic component of a certain physiological state. Therefore, circulating rare cells in combination may arise from yet, also account for systemic diseases, which we denote as multi-rare cell association and involves foremost bone marrow-derived progenitor and stem cells yet, also matured somatic cell types. One would expect immense diagnostic value in the read-out of the so called rare cell population which represents cytological evidence of abnormality. We hypothesize that comprehensive rare cell population profiling as contrasted to the biomarker screening approach may realize the premise of a biopsy as to confirm, characterize, grade, stage or predict a systemic disease. This novel approach represents the “missing link” in diagnostic care of in particular early or residual systemic disease and presumes a steady gain in knowledge about the clinical interpretation of rare cell population profiles thus, expecting the knowledge-driven transformation of cell-based liquid biopsy from suggestion to confirmation. We support our hypothesis by past findings made by others and us and provide insights how to interpret a certain rare cell population profile." @default.
• W3201064305 created "2021-09-27" @default.
• W3201064305 creator A5004824108 @default.
• W3201064305 creator A5043246899 @default.
• W3201064305 date "2021-11-01" @default.
• W3201064305 modified "2023-09-26" @default.
• W3201064305 title "Systemic cytology. A novel diagnostic approach for assessment of early systemic disease" @default.
• W3201064305 cites W1553632592 @default.
• W3201064305 cites W158322050 @default.
• W3201064305 cites W1973584383 @default.
• W3201064305 cites W1988250653 @default.
• W3201064305 cites W1990719089 @default.
• W3201064305 cites W1993523135 @default.
• W3201064305 cites W1996717633 @default.
• W3201064305 cites W1997688669 @default.
• W3201064305 cites W2008570370 @default.
• W3201064305 cites W2012185785 @default.
• W3201064305 cites W2014745029 @default.
• W3201064305 cites W2023506111 @default.
• W3201064305 cites W2028027497 @default.
• W3201064305 cites W2047442306 @default.
• W3201064305 cites W2065828260 @default.
• W3201064305 cites W2093829133 @default.
• W3201064305 cites W2097126143 @default.
• W3201064305 cites W2097490111 @default.
• W3201064305 cites W2104005622 @default.
• W3201064305 cites W2107680358 @default.
• W3201064305 cites W2107770231 @default.
• W3201064305 cites W2113551024 @default.
• W3201064305 cites W2114055462 @default.
• W3201064305 cites W2115564331 @default.
• W3201064305 cites W2116483002 @default.
• W3201064305 cites W2116779481 @default.
• W3201064305 cites W2123105952 @default.
• W3201064305 cites W2127151069 @default.
• W3201064305 cites W2144801666 @default.
• W3201064305 cites W2146122313 @default.
• W3201064305 cites W2152168811 @default.
• W3201064305 cites W2156517690 @default.
• W3201064305 cites W2168476365 @default.
• W3201064305 cites W2192613614 @default.
• W3201064305 cites W2342838576 @default.
• W3201064305 cites W2345978567 @default.
• W3201064305 cites W2571240316 @default.
• W3201064305 cites W2586407709 @default.
• W3201064305 cites W2751625431 @default.
• W3201064305 cites W2752013568 @default.
• W3201064305 cites W2809679353 @default.
• W3201064305 cites W2897090283 @default.
• W3201064305 cites W2917102036 @default.
• W3201064305 cites W2965860279 @default.
• W3201064305 cites W2995463114 @default.
• W3201064305 cites W3001425747 @default.
• W3201064305 cites W3013874873 @default.
• W3201064305 cites W3028695460 @default.
• W3201064305 cites W3045385411 @default.
• W3201064305 cites W3084346878 @default.
• W3201064305 cites W3092105632 @default.
• W3201064305 cites W3145359886 @default.
• W3201064305 cites W4244100041 @default.
• W3201064305 cites W4252437054 @default.
• W3201064305 doi "https://doi.org/10.1016/j.mehy.2021.110682" @default.
• W3201064305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34598097" @default.
• W3201064305 hasPublicationYear "2021" @default.
• W3201064305 type Work @default.
• W3201064305 sameAs 3201064305 @default.
• W3201064305 citedByCount "1" @default.
• W3201064305 countsByYear W32010643052022 @default.
• W3201064305 crossrefType "journal-article" @default.
• W3201064305 hasAuthorship W3201064305A5004824108 @default.
• W3201064305 hasAuthorship W3201064305A5043246899 @default.
• W3201064305 hasBestOaLocation W32010643051 @default.
• W3201064305 hasConcept C121608353 @default.
• W3201064305 hasConcept C126322002 @default.
• W3201064305 hasConcept C142724271 @default.
• W3201064305 hasConcept C203014093 @default.
• W3201064305 hasConcept C2775934546 @default.
• W3201064305 hasConcept C2777910003 @default.
• W3201064305 hasConcept C2779013556 @default.
• W3201064305 hasConcept C2779134260 @default.
• W3201064305 hasConcept C2779529041 @default.
• W3201064305 hasConcept C2781197716 @default.
• W3201064305 hasConcept C2908647359 @default.
• W3201064305 hasConcept C55493867 @default.
• W3201064305 hasConcept C61238886 @default.
• W3201064305 hasConcept C71924100 @default.
• W3201064305 hasConcept C86803240 @default.
• W3201064305 hasConcept C99454951 @default.
• W3201064305 hasConceptScore W3201064305C121608353 @default.
• W3201064305 hasConceptScore W3201064305C126322002 @default.
• W3201064305 hasConceptScore W3201064305C142724271 @default.
• W3201064305 hasConceptScore W3201064305C203014093 @default.
• W3201064305 hasConceptScore W3201064305C2775934546 @default.
• W3201064305 hasConceptScore W3201064305C2777910003 @default.
• W3201064305 hasConceptScore W3201064305C2779013556 @default.
• W3201064305 hasConceptScore W3201064305C2779134260 @default.
• W3201064305 hasConceptScore W3201064305C2779529041 @default.
• W3201064305 hasConceptScore W3201064305C2781197716 @default.

• next