Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201105134> ?p ?o ?g. }
- W3201105134 endingPage "2192" @default.
- W3201105134 startingPage "2179" @default.
- W3201105134 abstract "Postural instability and balance impairment are common in Parkinson's disease (PD). Multiple factors, such as increased tone, bradykinesia, freezing of gait, posture, axial stiffness, and involuntary appendicular movements, can affect balance. The recent studies found that PD patients have abnormal perception of self-motion in vestibular domain. We asked whether measures of balance function, such as perception of one's motion, correlate with specific movement disorders seen in PD. Moving retinal image or self-motion in space triggers the perception of self-motion. We measured one's linear motion (heading) perception when subjects were moved en bloc using a moving platform (vestibular heading). Similar motion perception was generated in the visual domain (visual heading) by having the subjects view a 3D optical flow with immersive virtual reality goggles. During both tasks, the subjects reported the motion direction in the two-alternative-forced-choice paradigm. The accuracy of perceived motion direction was calculated from the responses fitted to the psychometric function curves to estimate how accurately and precisely the subjects can perceive rightward versus leftward motion (i.e., threshold and slope). Response accuracies and psychometric parameters were correlated with the disease duration, disease severity (total Unified Parkinson's Disease Rating Scale-III, UPDRS-III), and tremor, rigidity, axial, gait/posture components of UPRDS-III. We also correlated heading perception with the number of falls and subjective assessment of balance confidence using the Activities-Specific Balance Component (ABC) Scale. Accuracy, threshold, and sensitivity of vestibular heading perception significantly correlated with the disease duration and severity, particularly the tremor. Correlations were stronger for leftward heading perception in the vestibular domain. The visual heading perception was correlated with ABC Scale, especially with its items concerning optic-flow processing. There was asymmetry in leftward versus rightward vestibular heading perception. The level of asymmetry correlated with the axial component of UPDRS-III. Differences in the clinical parameters that correlate with visual versus vestibular heading perception suggest that two heading perception processes have different mechanistic underpinnings. The correlation of discordance between vestibular and visual heading perception with disease severity and duration suggests that visual function can be utilized for balance rehab in PD patients." @default.
- W3201105134 created "2021-09-27" @default.
- W3201105134 creator A5004221076 @default.
- W3201105134 creator A5025745372 @default.
- W3201105134 creator A5040441660 @default.
- W3201105134 creator A5042760832 @default.
- W3201105134 creator A5058485280 @default.
- W3201105134 date "2021-09-23" @default.
- W3201105134 modified "2023-10-18" @default.
- W3201105134 title "Does visuospatial motion perception correlate with coexisting movement disorders in Parkinson’s disease?" @default.
- W3201105134 cites W135914324 @default.
- W3201105134 cites W1770375643 @default.
- W3201105134 cites W1833717060 @default.
- W3201105134 cites W1970520830 @default.
- W3201105134 cites W1974807964 @default.
- W3201105134 cites W1978382694 @default.
- W3201105134 cites W1983682862 @default.
- W3201105134 cites W1987149927 @default.
- W3201105134 cites W1993933043 @default.
- W3201105134 cites W1995772863 @default.
- W3201105134 cites W2009505043 @default.
- W3201105134 cites W2012065376 @default.
- W3201105134 cites W2017578733 @default.
- W3201105134 cites W2020469711 @default.
- W3201105134 cites W2023057624 @default.
- W3201105134 cites W2029165778 @default.
- W3201105134 cites W2033238331 @default.
- W3201105134 cites W2033266586 @default.
- W3201105134 cites W2035912487 @default.
- W3201105134 cites W2042871294 @default.
- W3201105134 cites W2047790933 @default.
- W3201105134 cites W2053594265 @default.
- W3201105134 cites W2063603727 @default.
- W3201105134 cites W2070195864 @default.
- W3201105134 cites W2074693012 @default.
- W3201105134 cites W2087575813 @default.
- W3201105134 cites W2094355474 @default.
- W3201105134 cites W2103125163 @default.
- W3201105134 cites W2103267935 @default.
- W3201105134 cites W2108504020 @default.
- W3201105134 cites W2108987128 @default.
- W3201105134 cites W2112318224 @default.
- W3201105134 cites W2112778327 @default.
- W3201105134 cites W2114022278 @default.
- W3201105134 cites W2114143667 @default.
- W3201105134 cites W2118059413 @default.
- W3201105134 cites W2128290688 @default.
- W3201105134 cites W2129467001 @default.
- W3201105134 cites W2133425050 @default.
- W3201105134 cites W2133692971 @default.
- W3201105134 cites W2140978740 @default.
- W3201105134 cites W2144432978 @default.
- W3201105134 cites W2148486620 @default.
- W3201105134 cites W2148675954 @default.
- W3201105134 cites W2148927972 @default.
- W3201105134 cites W2150130953 @default.
- W3201105134 cites W2157522178 @default.
- W3201105134 cites W2158900973 @default.
- W3201105134 cites W2164772540 @default.
- W3201105134 cites W2197923805 @default.
- W3201105134 cites W2219093241 @default.
- W3201105134 cites W2410884779 @default.
- W3201105134 cites W2417476499 @default.
- W3201105134 cites W250196685 @default.
- W3201105134 cites W2528551195 @default.
- W3201105134 cites W2564012386 @default.
- W3201105134 cites W2621322281 @default.
- W3201105134 cites W2749718288 @default.
- W3201105134 cites W2765570742 @default.
- W3201105134 cites W2768053002 @default.
- W3201105134 cites W2793165366 @default.
- W3201105134 cites W2901745715 @default.
- W3201105134 cites W2904287630 @default.
- W3201105134 cites W2938985551 @default.
- W3201105134 cites W2946348258 @default.
- W3201105134 cites W3093481648 @default.
- W3201105134 doi "https://doi.org/10.1007/s00415-021-10804-2" @default.
- W3201105134 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34554323" @default.
- W3201105134 hasPublicationYear "2021" @default.
- W3201105134 type Work @default.
- W3201105134 sameAs 3201105134 @default.
- W3201105134 citedByCount "6" @default.
- W3201105134 countsByYear W32011051342022 @default.
- W3201105134 countsByYear W32011051342023 @default.
- W3201105134 crossrefType "journal-article" @default.
- W3201105134 hasAuthorship W3201105134A5004221076 @default.
- W3201105134 hasAuthorship W3201105134A5025745372 @default.
- W3201105134 hasAuthorship W3201105134A5040441660 @default.
- W3201105134 hasAuthorship W3201105134A5042760832 @default.
- W3201105134 hasAuthorship W3201105134A5058485280 @default.
- W3201105134 hasBestOaLocation W32011051342 @default.
- W3201105134 hasConcept C142724271 @default.
- W3201105134 hasConcept C151800584 @default.
- W3201105134 hasConcept C15744967 @default.
- W3201105134 hasConcept C16568411 @default.
- W3201105134 hasConcept C168031717 @default.
- W3201105134 hasConcept C169760540 @default.
- W3201105134 hasConcept C190041318 @default.