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• W3201170026 endingPage "199" @default.
• W3201170026 startingPage "184" @default.
• W3201170026 abstract "Rheumatoid arthritis (RA) patients have almost twice the risk of heart failure (HF) as individuals without RA, even with adjustment for the presence of ischemic heart disease. Moreover, RA patients remain at a 2-fold higher risk of mortality from HF compared to non-RA patients. These observations suggest that RA-specific inflammatory pathways are significant contributors to this increased risk of HF. Herein we summarize the epidemiology of HF in RA patients, the differences in myocardial structure or function between RA patients and non-RA patients without clinical signs of HF, and data on the role of systemic and local inflammation in RA HF pathophysiology. We also discuss the impact of subduing inflammation through the use of RA disease-modifying therapies on HF and myocardial structure and function, emphasizing gaps in the literature and areas needing further research." @default.
• W3201170026 created "2021-09-27" @default.
• W3201170026 creator A5008408671 @default.
• W3201170026 creator A5033485687 @default.
• W3201170026 creator A5042617054 @default.
• W3201170026 date "2021-12-27" @default.
• W3201170026 modified "2023-09-25" @default.
• W3201170026 title "Myocardial Dysfunction and Heart Failure in Rheumatoid Arthritis" @default.
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