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• W3201200722 abstract "BACKGROUND Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide, and has relatively high recurrence rates. Few studies have been published on the clinical stages of recurrent HCC. AIM To assess the applicability of the Barcelona Clinic Liver Cancer (BCLC) staging for recurrent HCC and the need to establish clinical stage criteria for recurrent HCC. METHODS The clinicopathological data of 81 patients with recurrent HCC who were admitted to the Hospital of Guangxi Zhuang Autonomous Region from January 2013 to December 2017 were collected. The patients were divided into three groups according to the BCLC staging system as follows: (1) Group A with BCLC stage A, 51 patients; (2) Group B with BCLC stage B, 14 patients; and (3) Group C with BCLC stage C, 16 patients. The median time to tumor recurrence and the median overall survival were compared. RESULTS The median time to tumor recurrence in groups A, B, and C was 16 ± 1.5 mo, 10 ± 2.8 mo, and 6 ± 0.5 mo, respectively, with a statistically significant difference among them (χ2 = 70.144, P 0.05), although there were statistically significant differences between group A and group C and between group B and group C (χ2 = 62.110, and 19.972, P < 0.05). The median overall survival in groups A, B, and C were 42 ± 5.1 mo, 22 ± 3.1 mo, and 13 ± 1.8 mo, respectively, with a statistically significant difference among them (χ2 = 38.949, P < 0.05); there were statistically significant differences between group A and group B, group A and group C, and group B and group C (χ2 = 9.577, 37.172, and 7.183, respectively; P < 0.05). CONCLUSION There are different prognoses in recurrent HCC patients according to the BCLC staging. Therefore, BCLC staging is applicable to recurrent HCC and it is essential to formulate clinical stage criteria for recurrent HCC." @default.
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• W3201200722 date "2021-09-26" @default.
• W3201200722 modified "2023-09-24" @default.
• W3201200722 title "Clinical stages of recurrent hepatocellular carcinoma: A retrospective cohort study" @default.
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• W3201200722 doi "https://doi.org/10.12998/wjcc.v9.i27.8020" @default.
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