Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201215227> ?p ?o ?g. }
- W3201215227 endingPage "415" @default.
- W3201215227 startingPage "399" @default.
- W3201215227 abstract "Exercise exerts direct effects on the vasculature via the impact of hemodynamic forces on the endothelium, thereby leading to functional and structural adaptations that lower cardiovascular risk. The patterns of blood flow and endothelial shear stress during exercise lead to atheroprotective hemodynamic stimuli on the endothelium and contribute to adaptations in vascular function and structure. The structural adaptations observed in arterial lumen dimensions after prolonged exercise supplant the need for acute functional vasodilatation in case of an increase in endothelial shear stress due to repeated exercise bouts. In contrast, wall thickness is affected by rather systemic factors, such as transmural pressure modulated during exercise by generalized changes in blood pressure. Several mechanisms have been proposed to explain the exercise-induced benefits in patients with coronary artery disease (CAD). They include decreased progression of coronary plaques in CAD, recruitment of collaterals, enhanced blood rheological properties, improvement of vascular smooth muscle cell and endothelial function, and coronary blood flow. This review describes how exercise via alterations in hemodynamic factors influences vascular function and structure which contributes to cardiovascular risk reduction, and highlights which mechanisms are involved in the positive effects of exercise on CAD." @default.
- W3201215227 created "2021-09-27" @default.
- W3201215227 creator A5006939356 @default.
- W3201215227 creator A5021543870 @default.
- W3201215227 creator A5054473522 @default.
- W3201215227 creator A5059700503 @default.
- W3201215227 creator A5066697688 @default.
- W3201215227 creator A5079248793 @default.
- W3201215227 date "2021-09-26" @default.
- W3201215227 modified "2023-09-23" @default.
- W3201215227 title "Exercise-mediated adaptations in vascular function and structure: Beneficial effects in coronary artery disease" @default.
- W3201215227 cites W1484454705 @default.
- W3201215227 cites W1511758634 @default.
- W3201215227 cites W1538859899 @default.
- W3201215227 cites W1578545798 @default.
- W3201215227 cites W1580052517 @default.
- W3201215227 cites W1848464647 @default.
- W3201215227 cites W1967091709 @default.
- W3201215227 cites W1971856416 @default.
- W3201215227 cites W1972282285 @default.
- W3201215227 cites W1973638648 @default.
- W3201215227 cites W1978652177 @default.
- W3201215227 cites W1982893384 @default.
- W3201215227 cites W1985730052 @default.
- W3201215227 cites W1990752520 @default.
- W3201215227 cites W1991693297 @default.
- W3201215227 cites W1993758920 @default.
- W3201215227 cites W1994842962 @default.
- W3201215227 cites W1994871067 @default.
- W3201215227 cites W1997295778 @default.
- W3201215227 cites W1997407699 @default.
- W3201215227 cites W1999418609 @default.
- W3201215227 cites W2000470017 @default.
- W3201215227 cites W2000511060 @default.
- W3201215227 cites W2004145281 @default.
- W3201215227 cites W2009370492 @default.
- W3201215227 cites W2009583279 @default.
- W3201215227 cites W2011086865 @default.
- W3201215227 cites W2014171174 @default.
- W3201215227 cites W2014892421 @default.
- W3201215227 cites W2017043051 @default.
- W3201215227 cites W2017430925 @default.
- W3201215227 cites W2021952948 @default.
- W3201215227 cites W2025399287 @default.
- W3201215227 cites W2027412006 @default.
- W3201215227 cites W2029473862 @default.
- W3201215227 cites W2029853631 @default.
- W3201215227 cites W2030427025 @default.
- W3201215227 cites W2033806689 @default.
- W3201215227 cites W2039830661 @default.
- W3201215227 cites W2041572409 @default.
- W3201215227 cites W2049912746 @default.
- W3201215227 cites W2056458634 @default.
- W3201215227 cites W2059698594 @default.
- W3201215227 cites W2064727064 @default.
- W3201215227 cites W2067035539 @default.
- W3201215227 cites W2071965696 @default.
- W3201215227 cites W2072751592 @default.
- W3201215227 cites W2085122671 @default.
- W3201215227 cites W2090372317 @default.
- W3201215227 cites W2090412876 @default.
- W3201215227 cites W2093133341 @default.
- W3201215227 cites W2093313262 @default.
- W3201215227 cites W2094097385 @default.
- W3201215227 cites W2096190290 @default.
- W3201215227 cites W2096436012 @default.
- W3201215227 cites W2100646418 @default.
- W3201215227 cites W2101047147 @default.
- W3201215227 cites W2103737758 @default.
- W3201215227 cites W2106470692 @default.
- W3201215227 cites W2106633424 @default.
- W3201215227 cites W2110085208 @default.
- W3201215227 cites W2112336057 @default.
- W3201215227 cites W2112699659 @default.
- W3201215227 cites W2113082835 @default.
- W3201215227 cites W2113603387 @default.
- W3201215227 cites W2113991276 @default.
- W3201215227 cites W2114347737 @default.
- W3201215227 cites W2114488399 @default.
- W3201215227 cites W2116816843 @default.
- W3201215227 cites W2117589354 @default.
- W3201215227 cites W2118379071 @default.
- W3201215227 cites W2122824674 @default.
- W3201215227 cites W2125702693 @default.
- W3201215227 cites W2125983285 @default.
- W3201215227 cites W2131240139 @default.
- W3201215227 cites W2132903886 @default.
- W3201215227 cites W2134907826 @default.
- W3201215227 cites W2135364143 @default.
- W3201215227 cites W2146509675 @default.
- W3201215227 cites W2149447449 @default.
- W3201215227 cites W2150943707 @default.
- W3201215227 cites W2152724821 @default.
- W3201215227 cites W2152854119 @default.
- W3201215227 cites W2155065403 @default.
- W3201215227 cites W2156056333 @default.
- W3201215227 cites W2156920951 @default.
- W3201215227 cites W2157997274 @default.