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- W3201218478 abstract "Three types of trifluoromethylated pyrazolidines, pyrazolines, and pyrazoles can be synthesized via divergent reaction of β-CF3-1, 3-enyne with hydrazines. The reaction with simple hydrazine monohydrate or sulfonyl hydrazines as nucleophiles produces 1,3,4-trisubstituted pyrazolines, whereas the reaction with acetyl hydrazine as nucleophiles affords 1,4,5-trisubstituted pyrazolidines. Using phenylhydrazine or tert-butylhydrazine as a reaction partner, the products are easily oxidized to form 1,4,5-trisubstituted pyrazoles." @default.
- W3201218478 created "2021-09-27" @default.
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- W3201218478 date "2021-09-20" @default.
- W3201218478 modified "2023-09-27" @default.
- W3201218478 title "Synthesis of Trifluoromethylated Pyrazolidines, Pyrazolines and Pyrazoles via Divergent Reaction of β-CF<sub>3</sub>-1,3-Enynes with Hydrazines" @default.
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- W3201218478 doi "https://doi.org/10.1021/acs.orglett.1c02646" @default.
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