FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201220919> ?p ?o ?g. }

• W3201220919 abstract "While cytology-based screening programs have significantly reduced mortality and morbidity from cervical cancer, the global consensus is that primary human papillomavirus (HPV) testing increases detection of high-grade cervical intraepithelial neoplasia (CIN) and invasive cancer. However, the optimal triage strategy for HPV+ women to avoid over-referral to colposcopy may be setting specific. We compared absolute and relative risk (RR) of >CIN2/3 within 12 months of a negative cytologic result in women HPV16/18+ compared to those with a 12-other high-risk HPV (hrHPV) genotype to identify women at greatest risk of high-grade disease and permit less aggressive management of women with other hrHPV infections.Participants were 14,160 women aged 25-69 years with negative cytology participating in the COMparison of HPV genotyping And Cytology Triage (COMPACT) study. Women who were HPV16/18+ were referred to colposcopy. Those with a 12-other hrHPV type underwent repeat cytology after 6 months and those with >abnormal squamous cells of undetermined significance went to colposcopy.Absolute risk of >CIN2 in HPV16/18+ women was 19.5% (95% CI=12.4%-29.4%). In women 25-29 years and HPV16+ it was 40.0% (95% CI=11.8%-76.9%). Absolute risk of >CIN3 in women HPV16/18+ was 11.0% (95% CI=5.9%-19.6%). For women 30-39 years and HPV16+ it was 23.1% (95% CI=5.0%-53.8%). Overall risk of >CIN2, >CIN3 in women with a 12-other hrHPV HPV type was 5.6% (95% CI=3.1%-10.0%) and 3.4% (95% CI=1.6%-7.2%) respectively. RR of >CIN2, >CIN3 in HPV16/18+ vs. 12-other hrHPV was 3.5 (95% CI=1.7-7.3) and 3.3 (95% CI=1.2-8.8), respectively.Primary HPV screening with HPV16/18 partial genotyping is a promising strategy to identify women at current/future risk of >CIN2 in Japan without over-referral to colposcopy.Trial Registration: UMIN Clinical Trials Registry Identifier: UMIN000013203." @default.
• W3201220919 created "2021-09-27" @default.
• W3201220919 creator A5001877034 @default.
• W3201220919 creator A5009010132 @default.
• W3201220919 creator A5026383304 @default.
• W3201220919 creator A5043409097 @default.
• W3201220919 creator A5055949391 @default.
• W3201220919 creator A5072637751 @default.
• W3201220919 creator A5077400696 @default.
• W3201220919 date "2021-01-01" @default.
• W3201220919 modified "2023-10-01" @default.
• W3201220919 title "Evaluation of partial genotyping with HPV16/18 for triage of HPV positive, cytology negative women in the COMPACT study" @default.
• W3201220919 cites W1501337190 @default.
• W3201220919 cites W1914634823 @default.
• W3201220919 cites W1967933229 @default.
• W3201220919 cites W1985882656 @default.
• W3201220919 cites W1987816098 @default.
• W3201220919 cites W2026617482 @default.
• W3201220919 cites W2036210769 @default.
• W3201220919 cites W2055810034 @default.
• W3201220919 cites W2095250514 @default.
• W3201220919 cites W2096733107 @default.
• W3201220919 cites W2099023213 @default.
• W3201220919 cites W2111282014 @default.
• W3201220919 cites W2113593874 @default.
• W3201220919 cites W2121732950 @default.
• W3201220919 cites W2124586707 @default.
• W3201220919 cites W2127780961 @default.
• W3201220919 cites W2130297731 @default.
• W3201220919 cites W2138556740 @default.
• W3201220919 cites W2141319143 @default.
• W3201220919 cites W2159416556 @default.
• W3201220919 cites W2161243824 @default.
• W3201220919 cites W2162482957 @default.
• W3201220919 cites W2162602627 @default.
• W3201220919 cites W2167222579 @default.
• W3201220919 cites W2172748090 @default.
• W3201220919 cites W2220283749 @default.
• W3201220919 cites W2243803066 @default.
• W3201220919 cites W2289936626 @default.
• W3201220919 cites W2512321320 @default.
• W3201220919 cites W2519518149 @default.
• W3201220919 cites W2586692530 @default.
• W3201220919 cites W2607359198 @default.
• W3201220919 cites W2788488067 @default.
• W3201220919 cites W2788982635 @default.
• W3201220919 cites W2802492055 @default.
• W3201220919 cites W2803158386 @default.
• W3201220919 doi "https://doi.org/10.3802/jgo.2021.32.e86" @default.
• W3201220919 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8550923" @default.
• W3201220919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34708593" @default.
• W3201220919 hasPublicationYear "2021" @default.
• W3201220919 type Work @default.
• W3201220919 sameAs 3201220919 @default.
• W3201220919 citedByCount "3" @default.
• W3201220919 countsByYear W32012209192022 @default.
• W3201220919 countsByYear W32012209192023 @default.
• W3201220919 crossrefType "journal-article" @default.
• W3201220919 hasAuthorship W3201220919A5001877034 @default.
• W3201220919 hasAuthorship W3201220919A5009010132 @default.
• W3201220919 hasAuthorship W3201220919A5026383304 @default.
• W3201220919 hasAuthorship W3201220919A5043409097 @default.
• W3201220919 hasAuthorship W3201220919A5055949391 @default.
• W3201220919 hasAuthorship W3201220919A5072637751 @default.
• W3201220919 hasAuthorship W3201220919A5077400696 @default.
• W3201220919 hasBestOaLocation W32012209191 @default.
• W3201220919 hasConcept C104317684 @default.
• W3201220919 hasConcept C121608353 @default.
• W3201220919 hasConcept C126322002 @default.
• W3201220919 hasConcept C131872663 @default.
• W3201220919 hasConcept C135763542 @default.
• W3201220919 hasConcept C142724271 @default.
• W3201220919 hasConcept C185592680 @default.
• W3201220919 hasConcept C18823058 @default.
• W3201220919 hasConcept C194828623 @default.
• W3201220919 hasConcept C2776117191 @default.
• W3201220919 hasConcept C2776135927 @default.
• W3201220919 hasConcept C2777120189 @default.
• W3201220919 hasConcept C2777343196 @default.
• W3201220919 hasConcept C2778220009 @default.
• W3201220919 hasConcept C29456083 @default.
• W3201220919 hasConcept C31467283 @default.
• W3201220919 hasConcept C512399662 @default.
• W3201220919 hasConcept C55493867 @default.
• W3201220919 hasConcept C71924100 @default.
• W3201220919 hasConceptScore W3201220919C104317684 @default.
• W3201220919 hasConceptScore W3201220919C121608353 @default.
• W3201220919 hasConceptScore W3201220919C126322002 @default.
• W3201220919 hasConceptScore W3201220919C131872663 @default.
• W3201220919 hasConceptScore W3201220919C135763542 @default.
• W3201220919 hasConceptScore W3201220919C142724271 @default.
• W3201220919 hasConceptScore W3201220919C185592680 @default.
• W3201220919 hasConceptScore W3201220919C18823058 @default.
• W3201220919 hasConceptScore W3201220919C194828623 @default.
• W3201220919 hasConceptScore W3201220919C2776117191 @default.
• W3201220919 hasConceptScore W3201220919C2776135927 @default.
• W3201220919 hasConceptScore W3201220919C2777120189 @default.
• W3201220919 hasConceptScore W3201220919C2777343196 @default.
• W3201220919 hasConceptScore W3201220919C2778220009 @default.
• W3201220919 hasConceptScore W3201220919C29456083 @default.

• next